4.6 Review

Unanswered questions in cancer-associated thrombosis

Related references

Note: Only part of the references are listed.
Article Critical Care Medicine

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Summary: This study compared the efficacy and safety of rivaroxaban and dalteparin in the treatment of cancer-associated VTE. The results showed that the efficacy and safety of rivaroxaban and dalteparin were consistent with those previously reported with DOACs.

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Summary: In this systematic review, the study provides a comprehensive summary of the best available evidence on recurrence and bleeding risk between 6 and 12 months after cancer-associated VTE. Recurrent VTE remains common beyond 6 months, with varying rates, while major bleeding rates between 6 and 12 months were relatively low. The findings support continuing anticoagulation treatment beyond 6 months in patients with active cancer.

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Summary: The study compared medication persistence and adherence between low molecular weight heparin (LMWH) and direct oral anticoagulants (DOACs) in cancer-associated thrombosis (CAT) patients. Results showed that patients remained on DOACs longer than LMWH, but medication adherence was similar at PDC >= 80%, while higher in LMWH users at PDC >= 95%. Additionally, prescription copayments were higher on average for LMWH compared to DOACs.

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