4.2 Article

Phylodynamics of classical swine fever virus in Brazil

Journal

BRAZILIAN JOURNAL OF MICROBIOLOGY
Volume 53, Issue 2, Pages 1065-1075

Publisher

SPRINGER
DOI: 10.1007/s42770-022-00724-2

Keywords

Classical swine fever; Hog cholera; Phylogeny; Evolution

Categories

Funding

  1. Ministerio da Agricultura, Pecuaria e Abastecimento

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This study analyzed the genetic variations and spread of the classical swine fever virus during outbreaks in Northeast Brazil. The results showed that the virus has a continuous presence in Ceara state and has spread to other states. The Brazilian Northeast virus has specific polymorphisms that differentiate it from viruses isolated in other countries.
The classical swine fever virus is the etiologic agent of one of the diseases with the greatest impact on swine farming worldwide. An extensive area of Brazil is considered free of the disease, but some states in Northeast Brazil have registered outbreaks since 2001. The objective of this study was to analyze the genetic variations of the virus and its spread over time and space. Partial sequences of the viral E2 protein obtained from samples collected during the Brazilian outbreaks were compared with sequences from the GenBank database (NCBI). The results demonstrated the continuous presence of the virus in the state of Ceara, with diffusion to at least two other states. The Brazilian Northeast virus presents specific polymorphisms that separate it from viruses isolated in other countries.

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