4.6 Editorial Material

Introduction to the mini-symposium molecular neuropathology of meningioma

Related references

Note: Only part of the references are listed.
Article Oncology

Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Retrospective Analysis, Retrospectively and Prospectively Validated

Sybren L. N. Maas et al.

Summary: Utilizing DNA methylation and copy-number information for risk stratification in meningiomas improves prediction accuracy, with an integrated score showing higher precision, especially in risk separation of WHO grade 1 and grade 2 tumors.

JOURNAL OF CLINICAL ONCOLOGY (2021)

Article Multidisciplinary Sciences

A clinically applicable integrative molecular classification of meningiomas

Farshad Nassiri et al.

Summary: Meningiomas, the most common primary intracranial tumor in adults, often require surgery due to lack of effective medical therapies. This study introduced four consensus molecular groups of meningioma, which accurately predicted clinical outcomes and informed therapeutic options. Single-cell RNA sequencing revealed inter-individual variations in meningioma biology, highlighting the importance of molecular classification in guiding treatment strategies.

NATURE (2021)

Review Oncology

The 2021 WHO Classification of Tumors of the Central Nervous System: a summary

David N. Louis et al.

Summary: The fifth edition of the WHO Classification of Tumors of the Central Nervous System integrates molecular diagnostics into CNS tumor classification, introduces different approaches to tumor nomenclature and grading, and emphasizes the importance of integrated diagnoses and layered reports.

NEURO-ONCOLOGY (2021)

Article Multidisciplinary Sciences

Genomic Analysis of Non-NF2 Meningiomas Reveals Mutations in TRAF7, KLF4, AKT1, and SMO

Victoria E. Clark et al.

SCIENCE (2013)