Related references
Note: Only part of the references are listed.Alzheimer's disease brain-derived extracellular vesicles spread tau pathology in interneurons
Zhi Ruan et al.
BRAIN (2021)
An SPRi-based biosensor pilot study: Analysis of multiple circulating extracellular vesicles and hippocampal volume in Alzheimer's disease
Silvia Picciolini et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2021)
Early intraneuronal amyloid triggers neuron-derived inflammatory signaling in APP transgenic rats and human brain
Lindsay A. Welikovitch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Augmented COlorimetric NANoplasmonic (CONAN) Method for Grading Purity and Determine Concentration of EV Microliter Volume Solutions
Andrea Zendrini et al.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2020)
Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease
Ethan R. Roy et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
P2RX7 inhibitor suppresses exosome secretion and disease phenotype in P301S tau transgenic mice
Zhi Ruan et al.
MOLECULAR NEURODEGENERATION (2020)
Extracellular vesicles from amyloid-β exposed cell cultures induce severe dysfunction in cortical neurons
Chiara Beretta et al.
SCIENTIFIC REPORTS (2020)
Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake
Santra Brenna et al.
JOURNAL OF EXTRACELLULAR VESICLES (2020)
Copper Binding Regulates Cellular Prion Protein Function
Xuan T. A. Nguyen et al.
MOLECULAR NEUROBIOLOGY (2019)
Detrimental and protective action of microglial extracellular vesicles on myelin lesions: astrocyte involvement in remyelination failure
Marta Lombardi et al.
ACTA NEUROPATHOLOGICA (2019)
BIN1 favors the spreading of Tau via extracellular vesicles
Andrea Crotti et al.
SCIENTIFIC REPORTS (2019)
Extracellular Vesicles: Catching the Light in Zebrafish
Frederik J. Verweij et al.
TRENDS IN CELL BIOLOGY (2019)
Proteomic characterisation of leech microglia extracellular vesicles (EVs): comparison between differential ultracentrifugation and Optiprep™ density gradient isolation
T. Arab et al.
JOURNAL OF EXTRACELLULAR VESICLES (2019)
Aß42 Protofibrils Interact with and Are Trafficked through MicroglialDerived Microvesicles
Lisa K. Gouwens et al.
ACS CHEMICAL NEUROSCIENCE (2018)
Alzheimer's disease pathology propagation by exosomes containing toxic amyloid-beta oligomers
Maitrayee Sardar Sinha et al.
ACTA NEUROPATHOLOGICA (2018)
Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations
Ilaria Prada et al.
ACTA NEUROPATHOLOGICA (2018)
Cellular Receptors of Amyloid β Oligomers (AβOs) in Alzheimer's Disease
Barbara Mroczko et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles
Francesc X. Guix et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Shedding light on the cell biology of extracellular vesicles
Guillaume van Niel et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
Molecular interactions at the surface of extracellular vesicles
Edit I. Buzas et al.
SEMINARS IN IMMUNOPATHOLOGY (2018)
Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction
Laetitia Weinhard et al.
NATURE COMMUNICATIONS (2018)
Exosomes taken up by neurons hijack the endosomal pathway to spread to interconnected neurons
Juan Carlos Polanco et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2018)
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
Clotilde Thery et al.
JOURNAL OF EXTRACELLULAR VESICLES (2018)
The release and trans-synaptic transmission of Tau via exosomes
Yipeng Wang et al.
MOLECULAR NEURODEGENERATION (2017)
Late onset Alzheimer's disease genetics implicates microglial pathways in disease risk
Anastasia G. Efthymiou et al.
MOLECULAR NEURODEGENERATION (2017)
Microglia emerge as central players in brain disease
Michael W. Salter et al.
NATURE MEDICINE (2017)
Extracellular vesicle docking at the cellular port: Extracellular vesicle binding and uptake
Kinsley C. French et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2017)
Amyloid β-Exposed Human Astrocytes Overproduce Phospho-Tau and Overrelease It within Exosomes, Effects Suppressed by Calcilytic NPS 2143-Further Implications for Alzheimer's Therapy
Anna Chiarini et al.
FRONTIERS IN NEUROSCIENCE (2017)
Entorhinal Cortex dysfunction can be rescued by inhibition of microglial RAGE in an Alzheimer's disease mouse model
Chiara Criscuolo et al.
SCIENTIFIC REPORTS (2017)
Amyloid- Receptors: The Good, the Bad, and the Prion Protein
Heledd H. Jarosz-Griffiths et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Increase of Positive Net Charge and Conformational Rigidity Enhances the Efficacy of D-Enantiomeric Peptides Designed to Eliminate Cytotoxic Aβ Species
Tamar Ziehm et al.
ACS CHEMICAL NEUROSCIENCE (2016)
Neuroinflammation in Alzheimer's disease: Current evidence and future directions
Valeria Calsolaro et al.
ALZHEIMERS & DEMENTIA (2016)
A new approach to follow a single extracellular vesicle-cell interaction using optical tweezers
Ilaria Prada et al.
BIOTECHNIQUES (2016)
The Cellular Phase of Alzheimer's Disease
Bart De Strooper et al.
CELL (2016)
Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease
Claudio Villegas-Llerena et al.
CURRENT OPINION IN NEUROBIOLOGY (2016)
The amyloid hypothesis of Alzheimer's disease at 25years
Dennis J. Selkoe et al.
EMBO MOLECULAR MEDICINE (2016)
Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER
Wolf Heusermann et al.
JOURNAL OF CELL BIOLOGY (2016)
In Vivo Tau, Amyloid, and Gray Matter Profiles in the Aging Brain
Jorge Sepulcre et al.
JOURNAL OF NEUROSCIENCE (2016)
Accumulation of amyloid-β by astrocytes result in enlarged endosomes and microvesicle-induced apoptosis of neurons
Sofia Sollvander et al.
MOLECULAR NEURODEGENERATION (2016)
Therapeutic strategies for Alzheimer's disease in clinical trials
Justyna Godyn et al.
PHARMACOLOGICAL REPORTS (2016)
Complement and microglia mediate early synapse loss in Alzheimer mouse models
Soyon Hong et al.
SCIENCE (2016)
Extracellular vesicle-associated Aβ mediates trans-neuronal bioenergetic and Ca2+-handling deficits in Alzheimer's disease models
Erez Eitan et al.
NPJ AGING AND MECHANISMS OF DISEASE (2016)
Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis
G. Fossati et al.
CELL DEATH AND DIFFERENTIATION (2015)
Active endocannabinoids are secreted on extracellular membrane vesicles
Martina Gabrielli et al.
EMBO REPORTS (2015)
Neuroinflammation in Alzheimer's disease
Michael T. Heneka et al.
LANCET NEUROLOGY (2015)
Depletion of microglia and inhibition of exosome synthesis halt tau propagation
Hirohide Asai et al.
NATURE NEUROSCIENCE (2015)
Differential detergent sensitivity of extracellular vesicle subpopulations
Xabier Osteikoetxea et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2015)
Network neurodegeneration in Alzheimer's disease via MRI based shape diffeomorphometry and high-field atlasing
Michael Miller et al.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2015)
Myeloid Microvesicles in Cerebrospinal Fluid Are Associated with Myelin Damage and Neuronal Loss in Mild Cognitive Impairment and Alzheimer Disease
Federica Agosta et al.
ANNALS OF NEUROLOGY (2014)
Microglia convert aggregated amyloid-β into neurotoxic forms through the shedding of microvesicles
P. Joshi et al.
CELL DEATH AND DIFFERENTIATION (2014)
Amyloid Deposition Is Linked to Aberrant Entorhinal Activity among Cognitively Normal Older Adults
Willem Huijbers et al.
JOURNAL OF NEUROSCIENCE (2014)
Exosomes secreted by cortical neurons upon glutamatergic synapse activation specifically interact with neurons
Mathilde Chivet et al.
JOURNAL OF EXTRACELLULAR VESICLES (2014)
Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer's Disease
Bin Zhang et al.
CELL (2013)
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
Jean-Charles Lambert et al.
NATURE GENETICS (2013)
Variant of TREM2 Associated with the Risk of Alzheimer's Disease
Thorlakur Jonsson et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
TREM2 Variants in Alzheimer's Disease
Rita Guerreiro et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Current and future treatments for Alzheimer's disease
Konstantina G. Yiannopoulou et al.
THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS (2013)
Microvesicles released from microglia stimulate synaptic activity via enhanced sphingolipid metabolism
Flavia Antonucci et al.
EMBO JOURNAL (2012)
Mechanism of Evenness Interrupted (Evi)-Exosome Release at Synaptic Boutons
Kate Koles et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Trans-Synaptic Spread of Tau Pathology In Vivo
Li Liu et al.
PLOS ONE (2012)
Microglial Receptor for Advanced Glycation End Product-Dependent Signal Pathway Drives β-Amyloid-Induced Synaptic Depression and Long-Term Depression Impairment in Entorhinal Cortex
Nicola Origlia et al.
JOURNAL OF NEUROSCIENCE (2010)
Amyloid-β-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks
Jorge J. Palop et al.
NATURE NEUROSCIENCE (2010)
Transsynaptic Progression of Amyloid-β-Induced Neuronal Dysfunction within the Entorhinal-Hippocampal Network
Julie A. Harris et al.
NEURON (2010)
Selective Vulnerability of Neurons in Layer II of the Entorhinal Cortex during Aging and Alzheimer's Disease
Alexis M. Stranahan et al.
NEURAL PLASTICITY (2010)
Acid sphingomyelinase activity triggers microparticle release from glial cells
Fabio Bianco et al.
EMBO JOURNAL (2009)
A beta-Dependent Inhibition of LTP in Different Intracortical Circuits of the Visual Cortex: The Role of RAGE
Nicola Origlia et al.
JOURNAL OF ALZHEIMERS DISEASE (2009)
Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior
Dennis J. Selkoe
BEHAVIOURAL BRAIN RESEARCH (2008)
Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-β-mediated cortical synaptic dysfunction
Nicola Origlia et al.
JOURNAL OF NEUROSCIENCE (2008)
Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
Ganesh M. Shankar et al.
NATURE MEDICINE (2008)
Lipids revert inert Aβ amyloid fibrils to neurotoxic protofibrils that affect learning in mice
Ivo Cristiano Martins et al.
EMBO JOURNAL (2008)
Docosahexaenoic acid stabilizes soluble amyloid-β protofibrils and sustains amyloid-β-induced neurotoxicity in vitro
Ann-Sofi Johansson et al.
FEBS JOURNAL (2007)
Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
Heiko Braak et al.
ACTA NEUROPATHOLOGICA (2006)
Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment
Stephen W. Scheff et al.
NEUROBIOLOGY OF AGING (2006)
Neuroimaging as a marker of the onset and progression of Alzheimer's disease
JC Masdeu et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2005)
Molecular, structural, and functional characterization of Alzheimer's disease: Evidence for a relationship between default activity, amyloid, and memory
RL Buckner et al.
JOURNAL OF NEUROSCIENCE (2005)
Astrocyte-derived ATP induces vesicle shedding and IL-1β release from microglia
F Bianco et al.
JOURNAL OF IMMUNOLOGY (2005)
RAGE potentiates Aβ-induced perturbation of neuronal function in transgenic mice
O Arancio et al.
EMBO JOURNAL (2004)
Triple-transgenic model of Alzheimer's disease with plaques and tangles:: Intracellular Aβ and synaptic dysfunction
S Oddo et al.
NEURON (2003)
Structure-stability-function relationships of dendritic spines
H Kasai et al.
TRENDS IN NEUROSCIENCES (2003)
Alzheimer's disease is a synaptic failure
DJ Selkoe
SCIENCE (2002)
Phases of Aβ-deposition in the human brain and its relevance for the development of AD
DR Thal et al.
NEUROLOGY (2002)
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
DM Walsh et al.
NATURE (2002)
Soluble oligomers of β amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus
HW Wang et al.
BRAIN RESEARCH (2002)
Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease
E Masliah et al.
NEUROLOGY (2001)
Activation of synaptic NMDA receptors induces membrane insertion of new AMPA receptors and LTP in cultured hippocampal neurons
WY Lu et al.
NEURON (2001)