Related references
Note: Only part of the references are listed.Issues with Cancer Spheroid Models in Therapeutic Drug Screening
Eleonore Froehlich
CURRENT PHARMACEUTICAL DESIGN (2020)
Characterization of an Alginate Encapsulated LS180 Spheroid Model for Anti-colorectal Cancer Compound Screening
Tanya Smit et al.
ACS MEDICINAL CHEMISTRY LETTERS (2020)
Adenylate Kinase and Metabolic Signaling in Cancer Cells
Aleksandr Klepinin et al.
FRONTIERS IN ONCOLOGY (2020)
A Systematic Review of the Efficacy of Preclinical Models of Lung Cancer Drugs
Elizabeth Pan et al.
FRONTIERS IN ONCOLOGY (2020)
Leveraging and manufacturing in vitro multicellular spheroid-based tumor cell model as a preclinical tool for translating dysregulated tumor metabolism into clinical targets and biomarkers
Tong Wang et al.
BIORESOURCES AND BIOPROCESSING (2020)
U.S. EPA to eliminate all mammal testing by 2035
David Grimm
SCIENCE (2019)
The Tumor-on-Chip: Recent Advances in the Development of Microfluidic Systems to Recapitulate the Physiology of Solid Tumors
Grissel Trujillo-de Santiago et al.
MATERIALS (2019)
Three-dimensional cell culture systems as an in vitro platform for cancer and stem cell modeling
Nipha Chaicharoenaudomrung et al.
WORLD JOURNAL OF STEM CELLS (2019)
Halfway between 2D and Animal Models: Are 3D Cultures the Ideal Tool to Study Cancer-Microenvironment Interactions?
Jessica Hoarau-Vechot et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Epithelial-mesenchymal-transition-inducing transcription factors: new targets for tackling chemoresistance in cancer?
Jente van Staalduinen et al.
ONCOGENE (2018)
A Phase II Study of Irinotecan for Patients with Previously Treated Small-Cell Lung Cancer
Rie Kondo et al.
ONCOLOGY (2018)
Toxicity and anti-prolific properties of Xysmalobium undulatum water extract during short-term exposure to two-dimensional and three-dimensional spheroid cell cultures
Carlemi Calitz et al.
TOXICOLOGY MECHANISMS AND METHODS (2018)
The Microwell-mesh: A high-throughput 3D prostate cancer spheroid and drug-testing platform
E. O. Mosaad et al.
SCIENTIFIC REPORTS (2018)
Toxicity and anti-prolific properties of Xysmalobium undulatum water extract during short-term exposure to two-dimensional and three-dimensional spheroid cell cultures
Carlemi Calitz et al.
TOXICOLOGY MECHANISMS AND METHODS (2018)
Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning
Sigrid A. Langhans
FRONTIERS IN PHARMACOLOGY (2018)
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Freddie Bray et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2018)
Small cell lung cancer tumors and preclinical models display heterogeneity of neuroendocrine phenotypes
Wei Zhang et al.
TRANSLATIONAL LUNG CANCER RESEARCH (2018)
Survival changes in patients with small cell lung cancer and disparities between different sexes, socioeconomic statuses and ages
Shuncong Wang et al.
SCIENTIFIC REPORTS (2017)
Vitamin C in Stem Cell Biology: Impact on Extracellular Matrix Homeostasis and Epigenetics
Cristina D'Aniello et al.
STEM CELLS INTERNATIONAL (2017)
Extended topoisomerase 1 inhibition through liposomal irinotecan results in improved efficacy over topotecan and irinotecan in models of small-cell lung cancer
Shannon C. Leonard et al.
ANTI-CANCER DRUGS (2017)
Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis
Eric E. Gardner et al.
CANCER CELL (2017)
Adaptable stirred-tank culture strategies for large scale production of multicellular spheroid-based tumor cell models
Vitor E. Santo et al.
JOURNAL OF BIOTECHNOLOGY (2016)
Barasertib (AZD1152), a Small Molecule Aurora B Inhibitor, Inhibits the Growth of SCLC Cell Lines In Vitro and In Vivo
Barbara A. Helfrich et al.
MOLECULAR CANCER THERAPEUTICS (2016)
Quantitative Determination of Irinotecan and the Metabolite SN-38 by Nanoflow Liquid Chromatography-Tandem Mass Spectrometry in Different Regions of Multicellular Tumor Spheroids
Xin Liu et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2015)
Topotecan for Relapsed Small-cell Lung Cancer: Systematic Review and Meta-Analysis of 1347 Patients
Nobuyuki Horita et al.
Scientific Reports (2015)
Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012
Jacques Ferlay et al.
INTERNATIONAL JOURNAL OF CANCER (2015)
Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors
Rasheena Edmondson et al.
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2014)
Acquisition of epithelial-mesenchymal transition and cancer stem-like phenotypes within chitosan-hyaluronan membrane-derived 3D tumor spheroids
Yen-Jang Huang et al.
BIOMATERIALS (2014)
Tumor Cell Heterogeneity in Small Cell Lung Cancer (SCLC): Phenotypical and Functional Differences Associated with Epithelial-Mesenchymal Transition (EMT) and DNA Methylation Changes
Alexander Krohn et al.
PLOS ONE (2014)
Poly (ADP) ribose polymerase enzyme inhibitor, veliparib, potentiates chemotherapy and radiation in vitro and in vivo in small cell lung cancer
Taofeek K. Owonikoko et al.
CANCER MEDICINE (2014)
Small-cell lung cancer (SCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
M. Frueh et al.
ANNALS OF ONCOLOGY (2013)
Adenylate Kinase Release as a High-Throughput-Screening-Compatible Reporter of Bacterial Lysis for Identification of Antibacterial Agents
Anna C. Jacobs et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)
Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer
Rebekah L. Zinn et al.
MOLECULAR CANCER (2013)
Poly(β-amino ester) Nanoparticle Delivery of TP53 Has Activity against Small Cell Lung Cancer In Vitro and In Vivo
Chandrashekhar D. Kamat et al.
MOLECULAR CANCER THERAPEUTICS (2013)
Spheroid culture as a tool for creating 3D complex tissues
Eelco Fennema et al.
TRENDS IN BIOTECHNOLOGY (2013)
After trypsinisation, 3D spheroids of C3A hepatocytes need 18 days to re-establish similar levels of key physiological functions to those seen in the liver
Krzysztof Wrzesinski et al.
TOXICOLOGY RESEARCH (2013)
Molecular and cellular biology of neuroendocrine lung tumors: Evidence for separate biological entities
Dorian R. A. Swarts et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2012)
Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy
Geeta Mehta et al.
JOURNAL OF CONTROLLED RELEASE (2012)
NIH Image to ImageJ: 25 years of image analysis
Caroline A. Schneider et al.
NATURE METHODS (2012)
Determination of Drug Toxicity Using 3D Spheroids Constructed From an Immortal Human Hepatocyte Cell Line
Stephen J. Fey et al.
TOXICOLOGICAL SCIENCES (2012)
A German multicenter, randomized phase III trial comparing irinotecan-carboplatin with etoposide-carboplatin as first-line therapy for extensive-disease small-cell lung cancer
A. Schmittel et al.
ANNALS OF ONCOLOGY (2011)
The Fibroblast Growth Factor Receptor Inhibitor PD173074 Blocks Small Cell Lung Cancer Growth In vitro and In vivo
Olivier E. Pardo et al.
CANCER RESEARCH (2009)
The basics of epithelial-mesenchymal transition
Raghu Kalluri et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Drug ratio-dependent antitumor activity of irinotecan and cisplatin combinations in vitro and in vivo
Paul G. Tardi et al.
MOLECULAR CANCER THERAPEUTICS (2009)
Twenty-Seven Years of Phase III Trials for Patients with Extensive Disease Small-Cell Lung Cancer: Disappointing Results
Isao Oze et al.
PLOS ONE (2009)
Hedgehog signaling in small-cell lung cancer:: Frequent in vivo but a rare event in vitro
Janni Vestergaard et al.
LUNG CANCER (2006)
Phase I studies of imatinib mesylate combined with cisplatin and irinotecan in patients with small cell lung carcinoma
FM Johnson et al.
CANCER (2006)
The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy
GS Warshamana-Greene et al.
CLINICAL CANCER RESEARCH (2005)
Irinotecan: mechanisms of tumor resistance and novel strategies for modulating its activity
Y Xu et al.
ANNALS OF ONCOLOGY (2002)
Small cell lung carcinoma (SCLC) - A clinicopathologic study of 100 cases with surgical specimens
SA Nicholson et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2002)
Share Paper
