Related references
Note: Only part of the references are listed.Ion Selectivity in P2X Receptors: A Comparison between hP2X3 and zfP2X4
Vanesa Racigh et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2021)
Dissecting activation steps in P2X7 receptors
Milica Gusic et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2021)
Thermodynamics of Cation Binding to the Sarcoendoplasmic Reticulum Calcium ATPase Pump and Impacts on Enzyme Function
Bin Sun et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2019)
Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP
Mufeng Li et al.
ELIFE (2019)
Full-Length P2X7 Structures Reveal How Palmitoylation Prevents Channel Desensitization
Alanna E. McCarthy et al.
CELL (2019)
Purinergic receptors P2RX4 and P2RX7 in familial multiple sclerosis
A. Dessa Sadovnick et al.
HUMAN MUTATION (2017)
Intersubunit physical couplings fostered by the left flipper domain facilitate channel opening of P2X4 receptors
Jin Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Computational Assessment of Potassium and Magnesium Ion Binding to a Buried Pocket in GTPase-Associating Center RNA
Hamed S. Hayatshahi et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2017)
A water-mediated allosteric network governs activation of Aurora kinase A
Soreen Cyphers et al.
NATURE CHEMICAL BIOLOGY (2017)
Structural insights into the nucleotide base specificity of P2X receptors
Go Kasuya et al.
SCIENTIFIC REPORTS (2017)
How Native and Alien Metal Cations Bind ATP: Implications for Lithium as a Therapeutic Agent
Todor Dudev et al.
SCIENTIFIC REPORTS (2017)
Insights into the channel gating of P2X receptors from structures, dynamics and small molecules
Jin Wang et al.
ACTA PHARMACOLOGICA SINICA (2016)
The Dynamic Behavior of the P2X4 Ion Channel in the Closed Conformation
Gustavo Pierdominici-Sottile et al.
BIOPHYSICAL JOURNAL (2016)
A Highly Conserved Salt Bridge Stabilizes the Kinked Conformation of 2,3-Sheet Essential for Channel Function of P2X4 Receptors
Wen-Shan Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Molecular Mechanisms of Enzyme Activation by Monovalent Cations
David W. Gohara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
X-ray structures define human P2X3 receptor gating cycle and antagonist action
Steven E. Mansoor et al.
NATURE (2016)
Structural Insights into Divalent Cation Modulations of ATP-Gated P2X Receptor Channels
Go Kasuya et al.
CELL REPORTS (2016)
Purinergic P2X Receptors: Structural and Functional Features Depicted by X-Ray and Molecular Modelling Studies
Leanne Grimes et al.
CURRENT MEDICINAL CHEMISTRY (2015)
Na,K-ATPase α2 activity in mammalian skeletal muscle T-tubules is acutely stimulated by extracellular K+
Marino DiFranco et al.
JOURNAL OF GENERAL PHYSIOLOGY (2015)
XSEDE: Accelerating Scientific Discovery
John Towns et al.
COMPUTING IN SCIENCE & ENGINEERING (2014)
Direct Gating of ATP-activated Ion Channels (P2X2 Receptors) by Lipophilic Attachment at the Outer End of the Second Transmembrane Domain
Simon W. Rothwell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Conductance Simulation of the Purinergic P2X2, P2X4, and P2X7 Ionic Channels Using a Combined Brownian Dynamics and Molecular Dynamics Approach
Dmitry A. Turchenkov et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2014)
Inherent Dynamics of Head Domain Correlates with ATP-Recognition of P2X4 Receptors: Insights Gained from Molecular Simulations
Li-Dong Huang et al.
PLOS ONE (2014)
Relative motions between left flipper and dorsal fin domains favour P2X4 receptor activation
Wen-Shan Zhao et al.
NATURE COMMUNICATIONS (2014)
ATP and potassium ions: a deadly combination for astrocytes
David G. Jackson et al.
SCIENTIFIC REPORTS (2014)
PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data
Daniel R. Roe et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2013)
Inter- and intrasubunit interactions between transmembrane helices in the open state of P2X receptor channels
Gabriel Heymann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Involvement of P2X4 receptor in P2X7 receptor-dependent cell death of mouse macrophages
Ayumi Kawano et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Simulation of steady-state diffusion: Driving force ensured by dual control volumes or local equilibrium Monte Carlo
Zoltan Hato et al.
JOURNAL OF CHEMICAL PHYSICS (2012)
Gating properties of the P2X2a and P2X2b receptor channels: Experiments and mathematical modeling
Anmar Khadra et al.
JOURNAL OF GENERAL PHYSIOLOGY (2012)
Molecular mechanism of ATP binding and ion channel activation in P2X receptors
Motoyuki Hattori et al.
NATURE (2012)
Gating mechanism of a P2X4 receptor developed from normal mode analysis and molecular dynamics simulations
Juan Du et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Molecular and functional properties of P2X receptors-recent progress and persisting challenges
Karina Kaczmarek-Hajek et al.
PURINERGIC SIGNALLING (2012)
Magnesium basics
Wilhelm Jahnen-Dechent et al.
CLINICAL KIDNEY JOURNAL (2012)
Role of P2X4 receptors in synaptic strengthening in mouse CA1 hippocampal neurons
Andrew W. Baxter et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2011)
Activation and Regulation of Purinergic P2X Receptor Channels
Claudio Coddou et al.
PHARMACOLOGICAL REVIEWS (2011)
Graphical analysis of pH-dependent properties of proteins predicted using PROPKA
Michal Rostkowski et al.
BMC STRUCTURAL BIOLOGY (2011)
P2X4 receptors mediate PGE2 release by tissue-resident macrophages and initiate inflammatory pain
Lauriane Ulmann et al.
EMBO JOURNAL (2010)
Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assays
Makoto Tsuda et al.
MOLECULAR PAIN (2009)
Crystal structure of the ATP-gated P2X4 ion channel in the closed state
Toshimitsu Kawate et al.
NATURE (2009)
Up-Regulation of P2X4 Receptors in Spinal Microglia after Peripheral Nerve Injury Mediates BDNF Release and Neuropathic Pain
Lauriane Ulmann et al.
JOURNAL OF NEUROSCIENCE (2008)
Very fast prediction and rationalization of pKa values for protein-ligand complexes
Delphine C. Bas et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2008)
Dissecting the facilitator and inhibitor allosteric metal sites of the P2X4 receptor channel -: Critical roles of Cys132 for zinc potentiation and Asp138 for copper inhibition
Claudio Coddou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Automated Builder and Database of Protein/Membrane Complexes for Molecular Dynamics Simulations
Sunhwan Jo et al.
PLOS ONE (2007)
Influence of extracellular monovalent cations on pore and gating properties of P2X7 receptor-operated single-channel currents
T. Riedel et al.
BIOPHYSICAL JOURNAL (2007)
Multiple P2X receptors are involved in the modulation of apoptosis in human mesangial cells:: evidence for a role of P2X4
Anna Solini et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2007)
Carboxyl-terminal splicing enhances physical interactions between the cytoplasmic tails of purinergic P2X receptors
T Koshimizu et al.
MOLECULAR PHARMACOLOGY (2006)
Extracellular ATP-stimulated current in wild-type and P2X4 receptor transgenic mouse ventricular myocytes:: implications for a cardiac physiologic role of P2X4 receptors
Jian-Bing Shen et al.
FASEB JOURNAL (2006)
Heavy metals modulate the activity of the purinergic P2X4 receptor
C Coddou et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2005)
Action potential-independent release of glutamate by Ca2+ entry through presynaptic P2X receptors elicits postsynaptic firing in the brainstem autonomic network
E Shigetomi et al.
JOURNAL OF NEUROSCIENCE (2004)
Development and testing of a general amber force field
JM Wang et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Histidine 140 plays a key role in the inhibitory modulation of the P2X4 nucleotide receptor by copper but not zinc
C Coddou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury
M Tsuda et al.
NATURE (2003)
Neuromodulator role of zinc and copper during prolonged ATP applications to P2X4 purinoceptors
C Coddou et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2003)
Tissue distribution of P2X(4) receptors studied with an ectodomain antibody
XN Bo et al.
CELL AND TISSUE RESEARCH (2003)
Characterization of calcium signaling by purinergic receptor-channels expressed in excitable cells
TA Koshimizu et al.
MOLECULAR PHARMACOLOGY (2000)
Zinc and copper modulate differentially the P2X4 receptor
C Acuña-Castillo et al.
JOURNAL OF NEUROCHEMISTRY (2000)