SimPlot plus plus : a Python application for representing sequence similarity and detecting recombination

Motivation: Accurate detection of sequence similarity and homologous recombination are essential parts of many evolutionary analyses. Results: We have developed SimPlot++, an open-source multiplatform application implemented in Python, which can be used to produce publication quality sequence similarity plots using 63 nucleotide and 20 amino acid distance models, to detect intergenic and intragenic recombination events using Phi, Max-chi(2), NSS or proportion tests, and to generate and analyze interactive sequence similarity networks. SimPlot++ supports multicore data processing and provides useful distance calculability diagnostics.

Automated summary

SimPlot++ is an open-source multiplatform application that can generate publication quality sequence similarity plots, detect recombination events, and analyze sequence similarity networks.