Journal
BIOFOULING
Volume 38, Issue 4, Pages 321-330Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/08927014.2022.2064220
Keywords
Phosphates; fluorides; biofilms; Streptococcus mutans; Candida albicans; nanotechnology
Funding
- Coordination for the Improvement of Higher Education Personnel (CAPES) [001]
- PROCAD/CAPES [88881.068437/2014-01]
- National Council for Scientific and Technological Development (CNPq) [123611/2019-9]
Ask authors/readers for more resources
This study evaluated the effects of micrometric or nano-sized sodium hexametaphosphate, combined or not with fluoride, on dual-species biofilms of Streptococcus mutans and Candida albicans. The results showed that the nano-sized sodium hexametaphosphate and fluoride had stronger antibacterial effects on the biofilms.
This study evaluated the effects of micrometric or nano-sized sodium hexametaphosphate (HMPnano), combined or not with fluoride (NaF, 1100 ppm), on dual-species biofilms of Streptococcus mutans and Candida albicans. Biofilms were treated with solutions containing the polyphosphates at 0.5% or 1.0%, with/without fluoride (F), in addition to positive and negative controls. Biofilms were analysed by colony-forming units (CFU) counting, metabolic activity, production of biomass, composition of extracellular matrix, and structure. 1% HMPnano + F led to the lowest S. mutans CFU, while C. albicans CFU counts were not affected by any solution. 1% HMPnano led to the lowest metabolic activity, except for 1% HMPnano + F. All solutions promoted reductions in biofilm biomass compared to controls. Also, 1% HMPnano + F promoted the lowest concentrations of carbohydrates in the biofilm matrix, besides substantially affecting biofilms' structure. In conclusion, HMPnano and F promoted higher antibiofilm effects compared with its micrometric counterpart for most of the parameters assessed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available