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TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
TAB2 and TAB3 activate the NF-κB pathway through binding to polyubiquitin chains
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NATURE (2004)
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JOURNAL OF EXPERIMENTAL MEDICINE (2004)
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RIP1 is an essential mediator of Toll-like receptor 3-induced NF-κB activation
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NATURE IMMUNOLOGY (2004)
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NATURE (2003)
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CYLD is a deubiquitinating enzyme that negatively regulates NF-κB activation by TNFR family members
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
IKKε and TBK1 are essential components of the IRF3 signaling pathway
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Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3
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TAK1 is a ubiquitin-dependent kinase of MKK and IKK
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MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines
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Failure to regulate TNF-induced NF-κB and cell death responses in A20-deficient mice
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