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Catalytic Conversion of Furans and Pyrroles to Natural Products and Analogues Utilizing Donor-Acceptor Substituted Cyclopropanes as Key Intermediates

Journal

ISRAEL JOURNAL OF CHEMISTRY
Volume 56, Issue 6-7, Pages 531-539

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ijch.201500103

Keywords

donor-acceptor systems; furans; lactones; pyrroles; pyrrolidinones; gamma-butyrolactons

Funding

  1. Deutsche Forschungsgemeinschaft

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This review is an account of our work on developing stereoselective cyclopropanations of furans and pyrroles as a facile entry into donor-acceptor substituted cyclopropanes. The application of these building blocks for the synthesis of paraconic acids, sesquiterpene lactones, pyrrolidinones, and conformationally restricted -amino acids is discussed.

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