Journal
AUSTRALASIAN JOURNAL OF DERMATOLOGY
Volume 63, Issue 3, Pages E255-E258Publisher
WILEY
DOI: 10.1111/ajd.13856
Keywords
factor Xa inhibitors; genetic testing; mosaicism; quality of life; rivaroxaban; vascular malformations
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This case report presents a successful treatment of a venous malformation due to a variant in the TEK gene using low dose rivaroxaban, effectively controlling symptoms of chronic localized intravascular coagulation.
Low-flow vascular malformations are rare congenital anomalies due to errors in vascular development and may be associated with known pathogenic genetic variants. Slow flow through the blood vessels can lead to localized intralesional thromboses, which can cause debilitating pain and impair quality of life. We present a case of venous malformation due to a variant in the TEK gene in a 38-year-old woman in whom treatment with low dose rivaroxaban was successful in controlling symptoms of chronic localized intravascular coagulation.
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