4.5 Article

Cost-effectiveness of patient observation on cranial CT use with minor head trauma

Journal

ARCHIVES OF DISEASE IN CHILDHOOD
Volume 107, Issue 8, Pages 712-718

Publisher

BMJ PUBLISHING GROUP
DOI: 10.1136/archdischild-2021-323701

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Funding

  1. National Health and Medical Research Council, Canberra, Australia [GNT1046727]
  2. National Health and Medical Research Council (Centre of Research Excellence for Pediatric Emergency Medicine), Canberra, Australia [GNT1058560]
  3. Murdoch Children's Research Institute, Melbourne, Australia
  4. Emergency Medicine Foundation, Brisbane, Australia [EMPJ-11162]
  5. Perpetual Philanthropic Services, Australia [2012/1140]
  6. Auckland Medical Research Foundation, Auckland, New Zealand [3112011]
  7. WA Health Targeted Research Funds 2013, Perth, Australia
  8. A+ Trust (Auckland District Health Board), Auckland, New Zealand
  9. Townsville Hospital, Townsville, Australia
  10. Health Service Private Practice Research and Education Trust Fund, Townsville, Australia
  11. Victorian Government's Infrastructure Support Program, Melbourne, Australia
  12. Australian Government Research Training Program
  13. PREDICT CRE Research Higher Degree scholarship
  14. Royal Children's Hospital Foundation, Melbourne, Australia
  15. Melbourne Campus Clinician Scientist Fellowship, Melbourne, Australia
  16. NHMRC Practitioner Fellowship, Canberra, Australia
  17. Health Research Council of New Zealand [HRC13/556]

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The study found that planned observation in children with minor head trauma is cost-effective for reducing CT use, especially for those in the PECARN intermediate-risk and high-risk categories.
Objective To evaluate the cost-effectiveness of planned observation on cranial CT use in children with minor head trauma. Design Planned secondary analysis of a multicentre prospective observation study. Setting Australia and New Zealand. Patients An analytic cohort of 18 471 children aged <18 years with Glasgow Coma Scale scores 14-15 presenting <24 hours after blunt head trauma stratified by the Pediatric Emergency Care Applied Research Network (PECARN) traumatic brain injury (TBI) risk categories. Intervention A plan for observation and immediate CT scan were documented after the initial assessment. The planned observation group included those with planned observation and no immediate plan for CT. Main outcome measures Taking an Australian public-funded healthcare perspective, we estimated the cost-effectiveness of planned observation on the adjusted mean costs per child and CT use reduction by net benefit regression analysis using ordinary least squares with robust SEs and bootstrapping. All costs presented in 2018 euros. Results Planned observation in 4945 (27%) children was cost-saving of (sic)85 (95% CI -120 to -51) with 10.4% lower CT use (95% CI 9.6 to 11.2). This strategy was cost-saving for the PECARN high-risk (-(sic)757 (95% CI -961 to -554)) and intermediate-risk (-(sic)52 (95% CI -99 to -4.3)) categories, with 43% (95% CI 39 to 47) and 11% (95% CI 9.6 to 12.4) lower CT use, respectively. The very low-risk category incurred more cost of (sic)86 (95% CI 67 to 104) with planned observation and 0.05% lower CT use (95% CI -0.61 to 0.71). Conclusion Planned ED observation in selected children with minor head trauma is cost-effective for reducing CT use for the PECARN intermediate-risk and high-risk categories.

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