Journal
APPLIED OPTICS
Volume 61, Issue 15, Pages 4458-4462Publisher
Optica Publishing Group
DOI: 10.1364/AO.455626
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Funding
- National Institutes of Health [NIH-DP2HL127776]
- Columbia University (BiomedX Technology Accelerator Award, Research Initiatives for Science and Engineering)
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This article presents a customized deep convolutional neural network (CNN) for the classification of breast tissues in optical coherence tomography (OCT) scans, achieving high accuracy and specificity in breast cancer diagnostics.
Optical coherence tomography (OCT) is being investigated in breast cancer diagnostics as a real-time histology evaluation tool. We present a customized deep convolutional neural network (CNN) for classification of breast tissues in OCT B-scans. Images of human breast samples from mastectomies and breast reductions were acquired using a custom ultrahigh-resolutionOCTsystem with 2.72 mu m axial resolution and 5.52 mu m lateral resolution. The network achieved 96.7% accuracy, 92% sensitivity, and 99.7% specificity on a dataset of 23 patients. The usage of deep learning will be important for the practical integration ofOCTinto clinical practice. (C) 2022 Optica Publishing Group
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