Related references
Note: Only part of the references are listed.Phase 2 Trial of Iberdomide in Systemic Lupus Erythematosus
Joan T. Merrill et al.
NEW ENGLAND JOURNAL OF MEDICINE (2022)
First-in-Human, Single- and Multiple-Ascending-Dose Studies in Healthy Subjects to Assess Pharmacokinetics, Pharmacodynamics, and Safety/Tolerability of Iberdomide, a Novel Cereblon E3 Ligase Modulator
Ying Ye et al.
CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT (2021)
Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups
Yong-Fei Wang et al.
NATURE COMMUNICATIONS (2021)
Patient ancestry significantly contributes to molecular heterogeneity of systemic lupus erythematosus
Michelle D. Catalina et al.
JCI INSIGHT (2020)
Trans-Ancestral Fine-Mapping and Epigenetic Annotation as Tools to Delineate Functionally Relevant Risk Alleles at IKZF1 and IKZF3 in Systemic Lupus Erythematosus
Timothy J. Vyse et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Quantifying circulating Th17 cells by qPCR: potential as diagnostic biomarker for rheumatoid arthritis
Agata N. Burska et al.
RHEUMATOLOGY (2019)
Type I interferon gene signature test-low and -high patients with systemic lupus erythematosus have distinct gene expression signatures
P. Z. Brohawn et al.
LUPUS (2019)
IL-10 producing regulatory and helper T-cells in systemic lupus erythematosus
J. Geginat et al.
SEMINARS IN IMMUNOLOGY (2019)
A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos
Mary E. Matyskiela et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Epigenetic immune cell counting in human blood samples for immunodiagnostics
Udo Baron et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
Cereblon modulator iberdomide induces degradation of the transcription factors Ikaros and Aiolos: immunomodulation in healthy volunteers and relevance to systemic lupus erythematosus
Peter H. Schafer et al.
ANNALS OF THE RHEUMATIC DISEASES (2018)
Aiolos Overexpression in Systemic Lupus Erythematosus B Cell Subtypes and BAFF-Induced Memory B Cell Differentiation Are Reduced by CC-220 Modulation of Cereblon Activity
Yumi Nakayama et al.
JOURNAL OF IMMUNOLOGY (2017)
Patient subgroup identification for clinical drug development
Xin Huang et al.
STATISTICS IN MEDICINE (2017)
Anifrolumab, an Anti-Interferon-α Receptor Monoclonal Antibody, in Moderate-to-Severe Systemic Lupus Erythematosus
Richard Furie et al.
ARTHRITIS & RHEUMATOLOGY (2017)
Gene Expression and Pharmacodynamic Changes in 1,760 Systemic Lupus Erythematosus Patients From Two Phase III Trials of BAFF Blockade With Tabalumab
Robert W. Hoffman et al.
ARTHRITIS & RHEUMATOLOGY (2017)
Systemic lupus erythematosus
Arvind Kaul et al.
NATURE REVIEWS DISEASE PRIMERS (2016)
Sustained in vivo signaling by long-lived IL-2 induces prolonged increases of regulatory T cells
Charles J. M. Bell et al.
JOURNAL OF AUTOIMMUNITY (2015)
T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection
Eoin F. McKinney et al.
NATURE (2015)
An Ikaros Promoter Element with Dual Epigenetic and Transcriptional Activities
Elizabeth A. Perotti et al.
PLOS ONE (2015)
Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations
Chuan Wang et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2013)
Systematic identification of trans eQTLs as putative drivers of known disease associations
Harm-Jan Westra et al.
NATURE GENETICS (2013)
Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as Susceptibility Loci for Systemic Lupus Erythematosus in a Large-Scale Multiracial Replication Study
Christopher J. Lessard et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2012)
The Ikaros gene family: Transcriptional regulators of hematopoiesis and immunity
Liza B. John et al.
MOLECULAR IMMUNOLOGY (2011)
Ikaros enforces the costimulatory requirement for IL2 gene expression and is required for anergy induction in CD4+ T lymphocytes
Rajan M. Thomas et al.
JOURNAL OF IMMUNOLOGY (2007)
Expression of B-cell activating factor of the tumour necrosis factor family (BAFF) in T cells in active systemic lupus erythematosus: the role of BAFF in T cell-dependent B cell pathogenic autoantibody production
S. Morimoto et al.
RHEUMATOLOGY (2007)
Interleukin 2 gene transcription is regulated by Ikaros-induced changes in histone acetylation in anergic T cells
Sanmay Bandyopadhyay et al.
BLOOD (2007)
Association of increased interferon-inducible gene expression with disease activity and lupus nephritis in patients with systemic lupus erythematosus
Xuebing Feng et al.
ARTHRITIS AND RHEUMATISM (2006)
Activation of the interferon-α pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease
KA Kirou et al.
ARTHRITIS AND RHEUMATISM (2005)