Journal
ANNALS OF NONINVASIVE ELECTROCARDIOLOGY
Volume 27, Issue 3, Pages -Publisher
WILEY
DOI: 10.1111/anec.12960
Keywords
atrial fibrillation; BioMonitor III; catheter ablation; implantable loop recorder; insertable cardiac monitor; pulmonary vein isolation
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Funding
- Biotronik SE Co
- KG (Berlin, Germany) [FF047]
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This study evaluated the performance of the atrial fibrillation (AF) detection algorithm of BioMonitor III (BM3) in patients before and after catheter ablation of AF. The results showed that BM3 accurately detected AF burden and had a high correlation with the results obtained from Holter monitoring.
Background Insertable cardiac monitors (ICMs) are increasingly used to evaluate the atrial fibrillation (AF) burden after catheter ablation of AF. BioMonitor III (BM3) is an ICM with a long sensing vector, which enhances sensing capabilities. The AF detection algorithm of the BM3 is based on R-R interval variability. Objective To evaluate the performance of the AF detection algorithm of BM3 in patients before and after catheter ablation of AF using simultaneous Holter recordings. Methods In this prospective study, we enrolled patients scheduled for catheter ablation of paroxysmal or persistent AF. After BM3 implantation, patients had a 4 days Holter registration before and 3 months after ablation. All true AF episodes >= 2 min on the Holter were annotated and matched with BM3 detected AF detections. Results Thirty-one patients were enrolled (mean age 60 +/- 8, 74% male, 68% paroxysmal AF). Fifty-six Holter registrations were performed in 30 patients. Twelve patients demonstrated at least one true AF episode with a total AF duration of 570 h. The AF burden accuracy of BM3 before catheter ablation was 99.6%, with a duration sensitivity of 98.6% and a duration specificity of 99.9%. The AF burden accuracy of BM3 after catheter ablation was 99.8%, with a duration sensitivity of 90.2% and a duration specificity of 99.9%. Overall, the AF burden detected on the Holter and BM3 demonstrated a high Pearson correlation coefficient of 0.996. Conclusion BM3 accurately detects AF burden in patients before and after catheter ablation of AF.
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