4.7 Letter

Reply to Deep Brain Stimulation for Tremor: Direct Targeting of a Novel Imaging Biomarker

Related references

Note: Only part of the references are listed.
Article Clinical Neurology

Probabilistic Mapping Reveals Optimal Stimulation Site in Essential Tremor

Andreas Nowacki et al.

Summary: The objective of this study was to analyze individual clinical and neuroimaging data of patients undergoing deep brain stimulation for essential tremor and identify predictors of outcome and an optimal stimulation site. The results showed a cluster of optimal stimulation that significantly improved tremor and coincided with a normative structural connectivity-based cerebellothalamic tract.

ANNALS OF NEUROLOGY (2022)

Article Clinical Neurology

Personalizing Deep Brain Stimulation Using Advanced Imaging Sequences

Clemens Neudorfer et al.

Summary: Using FGATIR sequences, this study identified a thalamic hypointensity as a potential visual marker for deep brain stimulation (DBS). By analyzing 65 patients with essential tremor, the clinical utility of the hypointensity marker was validated, and it was found to predict the clinical outcome of DBS treatment.

ANNALS OF NEUROLOGY (2022)

Letter Clinical Neurology

Deep Brain Stimulation for Tremor: Direct Targeting of a Novel Imaging Biomarker

Erik H. Middlebrooks et al.

ANNALS OF NEUROLOGY (2022)

Editorial Material Clinical Neurology

Converging on a Neuromodulation Target for Tremor

Michael D. Fox et al.

ANNALS OF NEUROLOGY (2022)

Article Neuroimaging

Connectivity correlates to predict essential tremor deep brain stimulation outcome: Evidence for a common treatment pathway

Erik H. Middlebrooks et al.

Summary: This study found a correlation between structural connectivity and treatment outcomes in DBS for tremor patients, suggesting the potential for structural connectivity to predict contralateral tremor improvement. The predictive feature map showed the anatomical course of the DRTT, with all analyzed sweet spots overlapping this predictive tract.

NEUROIMAGE-CLINICAL (2021)