4.8 Article

CRISPR-Cas12a-Derived Photoelectrochemical Biosensor for Point-Of-Care Diagnosis of Nucleic Acid

Related references

Note: Only part of the references are listed.
Article Chemistry, Analytical

Efficient Curing Sacrificial Agent-Induced Dual-Heterojunction Photoelectrochemical System for Highly Sensitive Immunoassay

Min Chen et al.

Summary: A novel curing sacrificial agent-induced dual-heterojunction photoelectrochemical system was proposed for highly sensitive detection of prostate-specific antigen (PSA). This system exhibited excellent photocurrent performance and a low detection limit, providing a new opportunity for the development of biosensors in the PEC field.

ANALYTICAL CHEMISTRY (2021)

Article Chemistry, Analytical

Double ion-exchange reaction-based photoelectrochemical immunoassay for sensitive detection of prostate-specific antigen

Ling Zhu et al.

Summary: This study developed a double ion-exchange reaction-based photoelectrochemical immunoassay for sensitive detection of PSA using a split-type detection mode. The assay showed good photocurrent responses towards target PSA with a low LOD, high specificity, and satisfactory accuracy compared to ELISA kits. The Cu2+-activated double ion-exchange reaction-based PEC immunoassay holds promise as a platform for biomarker detection.

ANALYTICA CHIMICA ACTA (2021)

Article Chemistry, Multidisciplinary

Single-Atom-Based Heterojunction Coupling with Ion-Exchange Reaction for Sensitive Photoelectrochemical Immunoassay

Ying Qin et al.

Summary: Single-atom catalysts, especially platinum single atoms (Pt SAs), show great potential in catalyst design, with Pt SAs supported by nanomaterials demonstrating superior performance, particularly in photoelectrochemical biosensing, enhancing detection sensitivity for specific analytes.

NANO LETTERS (2021)

Article Chemistry, Physical

CRISPR-Cas12a-driven MXene-PEDOT:PSS piezoresistive wireless biosensor

Ruijin Zeng et al.

Summary: This study introduces a CRISPR-Cas12a-based instrument-free point-of-care detection technology, which uses smartphone for visualized DNA detection results, and combines wireless sensing technology, significantly improving portability and detection sensitivity.

NANO ENERGY (2021)

Article Chemistry, Analytical

Rapid Point-of-Care COVID-19 Diagnosis with a Gold-Nanoarchitecture-Assisted Laser-Scribed Graphene Biosensor

Tutku Beduk et al.

Summary: LSG-based biosensing platforms show great potential as point-of-care diagnostic tools for COVID-19 due to their advantages in miniaturization, ease of operation, accessibility, and systematic data management. This alternative solution offers faster results compared to commercial diagnostic tools and demonstrates promising applications for future POC diagnostics.

ANALYTICAL CHEMISTRY (2021)

Article Chemistry, Multidisciplinary

Versatile Synthesis of Hollow Metal Sulfides via Reverse Cation Exchange Reactions for Photocatalytic CO2 Reduction

Ruijin Zeng et al.

Summary: A novel growth strategy for fabricating hollow multinary metal sulfide using a Cu2-xS nanocube template-assisted and reverse cation exchange-mediated method was explored. Experimental and theoretical calculations demonstrated that the obtained hollow metal sulfide semiconductors significantly improve the separation and migration of photogenerated electron-hole pairs, leading to outstanding photocatalytic performance.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Analytical

An ultrasensitive homogeneous electrochemical biosensor based on CRISPR-Cas12a

Jie Liu et al.

Summary: A simple, immobilization-free, highly sensitive, and homogeneous electrochemical biosensor for the detection of HPV-16 has been developed by utilizing the high-efficiency ssDNA cleavage activity of Cas12a in combination with MB-labeled probes. The sensor works by detecting the differential diffusion rate of MB-labeled DNA on the electrode, which is correlated with the HPV-16 concentration. The detection limit is determined to be 3.22 pM with a wide dynamic working range from 0.01 nM to 100 nM, and the detection process can be completed within 50 minutes at ambient temperature, outperforming previously reported HPV-based biosensors.

ANALYTICAL METHODS (2021)

Article Chemistry, Multidisciplinary

Functional DNA Regulated CRISPR-Cas12a Sensors for Point-of-Care Diagnostics of Non-Nucleic-Acid Targets

Ying Xiong et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Article Chemistry, Physical

Fabrication of In2O3/In2S3 microsphere heterostructures for efficient and stable photocatalytic nitrogen fixation

Huichang Xu et al.

APPLIED CATALYSIS B-ENVIRONMENTAL (2019)

Article Chemistry, Analytical

Palindromic Molecular Beacon Based Z-Scheme BiOCI-Au-CdS Photoelectrochemical Biodetection

Ruijin Zeng et al.

ANALYTICAL CHEMISTRY (2019)

Article Multidisciplinary Sciences

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

Janice S. Chen et al.

SCIENCE (2018)

Article Chemistry, Analytical

Uric Acid Monitoring with a Smartphone as the Electrochemical Analyzer

Jinhong Guo

ANALYTICAL CHEMISTRY (2016)

Review Chemistry, Analytical

Smartphone-based biosensors: A critical review and perspectives

Aldo Roda et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2016)