Journal
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 414, Issue 9, Pages 2953-2969Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-022-03960-5
Keywords
Ochratoxin A; Aptasensors; Nanomaterials; Detection
Funding
- National Natural Science Foundation of China [931702218, 31701694]
- Young and Middle-aged Leading Scientists, Engineers and Innovators of the XPCC [2019CB017]
- Natural Science Foundation of Henan Province [202300410121, 182300410038]
- Foundation for University Young Key Teacher Program of Henan Province [2018GGJS048]
- Youth Talent Support Project of Henan Province [112020HYTP029]
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This review summarizes the development of nanomaterial-based aptasensors for Ochratoxin A (OTA) determination and sample treatment over the past 5 years. Various nanomaterials, including metal, carbon, luminescent, magnetic, and other types, have been used in OTA aptasensors. The limitations and future challenges in developing nanomaterial-based OTA aptasensors are also discussed.
Ochratoxin A (OTA) is a widely distributed mycotoxin that often contaminates food, grains and animal feed. It poses a serious threat to human health because of its high toxicity and persistence. Therefore, the development of an inexpensive, highly sensitive, accurate and rapid method for OTA detection is imperative. In recent years, various nanomaterials used in the establishment of aptasensors have attracted great attention due to their large surface-to-volume ratio, good stability and facile preparation. This review summarizes the development of nanomaterial-based aptasensors for OTA determination and sample treatment over the past 5 years. The nanomaterials used in OTA aptasensors include metal, carbon, luminescent, magnetic and other nanomaterials. Finally, the limitations and future challenges in the development of nanomaterial-based OTA aptasensors are reviewed and discussed.
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