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A nuclease-resistant RNA aptamer specifically inhibits angiopoietin-1-mediated Tie2 activation and function
Rebekah R. White et al.
ANGIOGENESIS (2008)
Determination of Ochratoxin A with a DNA Aptamer
Jorge A. Cruz-Aguado et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2008)
Engineering Complex Riboswitch Regulation by Dual Genetic Selection
Vandana Sharma et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Model-guided design of ligand-regulated RNAi for programmable control of gene expression
Chase L. Beisel et al.
MOLECULAR SYSTEMS BIOLOGY (2008)
Structural insights into amino acid binding and gene control by a lysine riboswitch
Alexander Serganov et al.
NATURE (2008)
Biotinylation reagents for the study of cell surface proteins
Giuliano Elia
PROTEOMICS (2008)
Crystal structure of an RNA aptamer bound to thrombin
Stephen B. Long et al.
RNA (2008)
Improvement of aptamer affinity by dimerization
Hijiri Hasegawa et al.
SENSORS (2008)
Multidomain targeting generates a high-affinity thrombin-inhibiting bivalent aptamer
Jens Mueller et al.
CHEMBIOCHEM (2007)
Elucidation of the RNA target of linezolid by using a linezolid-neomycin B heteroconjugate and genomic SELEX
Hyun Jin Kim et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2007)
Selection of aptamers for molecular recognition and characterization of cancer cells
Zhiwen Tang et al.
ANALYTICAL CHEMISTRY (2007)
Specificity in protein interactions and its relationship with sequence diversity and coevolution
Luke Hakes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The origins of femtomolar protein-ligand binding: Hydrogen-bond cooperativity and desolvation energetics in the biotin-(strept)avidin binding site
Jason DeChancie et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Unnatural base pair systems for DNA/RNA-based biotechnology
Ichiro Hirao
CURRENT OPINION IN CHEMICAL BIOLOGY (2006)
Crystal structures of the thi-box riboswitch bound to thiamine pyrophosphate analogs reveal adaptive RNA-small molecule recognition
Thomas E. Edwards et al.
STRUCTURE (2006)
Aptamers evolved from live cells as effective molecular probes for cancer study
Dihua Shangguan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease
EWM Ng et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Comparison of different strategies to select aptamers against a transmembrane protein target
Carine Pestourie et al.
OLIGONUCLEOTIDES (2006)
In vitro selection of DNA aptamers binding ethanolamine
D Mann et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Size, constant sequences, and optimal selection
M Legiewicz et al.
RNA (2005)
Stable and selective formation of Hoogsteen-type triplexes and duplexes using twisted intercalating nucleic acids (TINA) prepared via postsynthetic sonogashira solid-phase coupling reactions
VV Filichev et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
The kinetics of ligand binding by an adenine-sensing riboswitch
JK Wickiser et al.
BIOCHEMISTRY (2005)
Deconvolution of a complex target using DNA aptamers
S Fitter et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Capillary electrophoresis-SELEX selection of aptamers with affinity for HIV-1 reverse transcriptase
RK Mosing et al.
ANALYTICAL CHEMISTRY (2005)
Selection of RNA aptamers against human influenza virus hemagglutinin using surface plasmon resonance
TS Misono et al.
ANALYTICAL BIOCHEMISTRY (2005)
The speed of RNA transcription and metabolite binding kinetics operate an FMN riboswitch
JK Wickiser et al.
MOLECULAR CELL (2005)
Direct in vitro selection of a 2 '-O-methyl aptamer to VEGF
PE Burmeister et al.
CHEMISTRY & BIOLOGY (2005)
New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control
JE Barrick et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Control of gene expression by a natural metabolite-responsive ribozyme
WC Winkler et al.
NATURE (2004)
Sialyllactose-binding modified DNA aptamer bearing additional functionality by SELEX
MM Masud et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2004)
Dissecting the cholera toxin-ganglioside GM1 interaction by isothermal titration calorimetry
WB Turnbull et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
A theophylline responsive riboswitch based on helix slipping controls gene expression in vivo
B Suess et al.
NUCLEIC ACIDS RESEARCH (2004)
In vitro evolution of functional DNA using capillary electrophoresis
SD Mendonsa et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Adenine riboswitches and gene activation by disruption of a transcription terminator
M Mandal et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Coenzyme B-12 riboswitches are widespread genetic control elements in prokaryotes
A Nahvi et al.
NUCLEIC ACIDS RESEARCH (2004)
A glycine-dependent riboswitch that uses cooperative binding to control gene expression
M Mandal et al.
SCIENCE (2004)
Evolution of aptamers with secondary structures from a new specificity and new an ATP aptamer
Z Huang et al.
RNA (2003)
An mRNA structure that controls gene expression by binding S-adenosylmethionine
WC Winkler et al.
NATURE STRUCTURAL BIOLOGY (2003)
Regulation of the vitamin B12 metabolism and transport in bacteria by a conserved RNA structural element
AG Vitreschak et al.
RNA (2003)
Riboswitches control fundamental biochemical pathways in Bacillus subtilis and other bacteria
M Mandal et al.
CELL (2003)
Encapsulating streptomycin within a small 40-mer RNA
V Tereshko et al.
CHEMISTRY & BIOLOGY (2003)
LNA: a versatile tool for therapeutics and genomics
M Petersen et al.
TRENDS IN BIOTECHNOLOGY (2003)
An mRNA structure in bacteria that controls gene expression by binding lysine
N Sudarsan et al.
GENES & DEVELOPMENT (2003)
An mRNA structure that controls gene expression by binding FMN
WC Winkler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Sensing small molecules by nascent RNA: A mechanism to control transcription in bacteria
AS Mironov et al.
CELL (2002)
Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression
W Winkler et al.
NATURE (2002)
Isolation of high-affinity GTP aptamers from partially structured RNA libraries
JH Davis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
In vitro selection of RNA aptamers that bind to cell adhesion receptors of Trypanosoma cruzi and inhibit cell invasion
H Ulrich et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Generation of species cross-reactive aptamers using toggle SELEX
R White et al.
MOLECULAR THERAPY (2001)
Pharmacokinetics and safety of an anti-vascular endothelial growth factor aptamer (NX1838) following injection into the vitreous humor of rhesus monkeys
DW Drolet et al.
PHARMACEUTICAL RESEARCH (2000)
In vitro selection of DNA aptamers which bind to cholic acid
T Kato et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2000)
2.8 Å crystal structure of the malachite green aptamer
C Baugh et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
Towards the selection of phosphorothioate aptamers -: Optimizing in vitro selection steps with phosphorothioate nucleotides
ML Andreola et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)
Design and optimization of effector-activated ribozyme ligases
Michael P. Robertson et al.
NUCLEIC ACIDS RESEARCH (2000)
Biochemistry - Adaptive recognition by nucleic acid aptamers
T Hermann et al.
SCIENCE (2000)
Specificity in protein-protein interactions: The structural basis for dual recognition in endonuclease colicin-immunity protein complexes
UC Kuhlmann et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)