Risk factors for severe reactions in food allergy: Rapid evidence review with meta-analysis

Letter Allergy

IgE-sensitization predicts threshold but not anaphylaxis during oral food challenges to cow's milk

Paul J. Turner et al.

ALLERGY (2022)

Add to Collection

Letter Allergy

Life-threatening anaphylaxis to peanut - impossible to predict? Reply

Alexandra F. Santos et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2022)

Add to Collection

Letter Allergy

Life-threatening anaphylaxis to peanut - impossible to predict?

Paul J. Turner et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2022)

Add to Collection

Article Allergy

Safety of peanut (Arachis hypogaea) allergen powder-dnfp in children and teenagers with peanut allergy: Pooled summary of phase 3 and extension trials

Kari R. Brown et al.

Summary: This study provides a comprehensive summary of the safety profile of PTAH treatment for up to 2 years. The results demonstrate that PTAH is well-tolerated and the frequency of adverse events decreases over time, with most events being mild or moderate in severity.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2022)

Add to Collection

Article Allergy

Oral anaphylaxis to peanut in a mouse model is associated with gut permeability but not with Tlr4 or Dock8 mutations

Jake A. Gertie et al.

Summary: This study aims to determine the mechanism underlying the unique susceptibility to anaphylaxis in C3H/HeJ mice and test the impact of Tlr4 and Dock8 mutations. The results showed increased gut permeability and an increased number of goblet cells in the small intestine of C3H/HeJ mice compared to C57BL/6 mice, leading to the entry of ingested allergens into the bloodstream and triggering anaphylactic reactions.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2022)

Add to Collection

Article Allergy

Peanut Can Be Used as a Reference Allergen for Hazard Characterization in Food Allergen Risk Management: A Rapid Evidence Assessment and Meta-Analysis

Paul J. Turner et al.

Summary: Regional and national legislation require the disclosure of priority allergens in foods, but unintentional allergen presence is not regulated. Precautionary allergen labels (PAL) are frequently ignored by food-allergic consumers. Establishing internationally agreed reference doses and conducting hazard characterization at low-level allergen exposure can aid in better allergen risk management and the use of PAL.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2022)

Add to Collection

Article Allergy

Combining Allergen Components Improves the Accuracy of Peanut Allergy Diagnosis

Oliver Hemmings et al.

Summary: Combining sIgE to multiple allergen components (Ara h 1, 2, 3, and 6) is highly predictive of peanut allergy and superior to individual markers. These models can be applied in real time during clinical consultations.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2022)

Add to Collection

Review Allergy

Reproducibility of food challenge to cow's milk: Systematic review with individual participant data meta-analysis

Paul J. Turner et al.

Summary: Cow's milk is a common cause of severe allergic reactions, but the severity of reactions at low-level exposure and the reproducibility of reaction thresholds are uncertain. This study found that about 5% of individuals with allergic reactions to low-level cow's milk protein may experience anaphylaxis. Most of these anaphylactic reactions are mild and can be treated with a single dose of epinephrine.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2022)

Add to Collection

Review Allergy

Association Between Severity of Anaphylaxis and Co-occurrence of Respiratory Diseases: A Systematic Review and Meta-analysis of Observational Studies

M. A. Tejedor-Alonso et al.

Summary: Respiratory diseases, especially asthma and COPD, increase the severity of anaphylaxis. While studies do not typically assess the importance of asthma severity, these conditions do have an impact on the severity of anaphylaxis.

JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY (2021)

Add to Collection

Letter Allergy

Seasonality of food-related anaphylaxis admissions and associations with temperature and pollen levels

Holly C. Y. Lam et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2021)

Add to Collection

Article Allergy

Heritable risk for severe anaphylaxis associated with increased α-tryptase-encoding germline copy number at TPSAB1

Jonathan J. Lyons et al.

Summary: This study revealed that genotypes have a significant impact on the severity of anaphylaxis in humans, particularly in association with H alpha T. The prevalence of H alpha T was higher in healthy individuals and controls with nonatopic disease, and it was particularly prominent in systemic mastocytosis and idiopathic anaphylaxis, suggesting it as a potential risk factor for severe allergic reactions.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2021)

Add to Collection

Article Allergy

Cardiovascular changes during peanut-induced allergic reactions in human subjects

Monica Ruiz-Garcia et al.

Summary: A systematic evaluation of cardiovascular changes during acute allergic reactions to peanut showed significant fluid redistribution regardless of reaction severity, with changes in stroke volume, heart rate, and peripheral blood flow. Administration of intravenous fluids reversed these changes and accelerated symptom resolution.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2021)

Add to Collection

Article Pediatrics

The usefulness of molecular diagnosis in the assessment of the aetiology, clinical phenotypes and risk of food-induced anaphylaxis in children

Lukasz Blazowski et al.

Summary: This study conducted molecular diagnosis of food-induced anaphylaxis in children, identifying characteristics and common allergens in different age groups, as well as exploring factors leading to severe clinical reactions. Molecular diagnostics allow for a detailed assessment of the aetiology and risk of severe food-induced anaphylaxis.

PEDIATRIA I MEDYCYNA RODZINNA-PAEDIATRICS AND FAMILY MEDICINE (2021)

Add to Collection

Article Allergy

Walnut Allergy Across Europe: Distribution of Allergen Sensitization Patterns and Prediction of Severity

Sarah A. Lyons et al.

Summary: This study investigates geographical differences in walnut component sensitization and cosensitization patterns among walnut-allergic subjects in Europe. A predictive model combining results from component-based serology testing with clinical background information can effectively discriminate between mild to moderate and severe walnut allergy.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2021)

Add to Collection

Article Allergy

Added Diagnostic Value of Peanut Component Testing: A Cross-Sectional Study in Australian Children

Narinder Kaur et al.

Summary: This study found that sensitization to a combination of Ara h 1, 2, and 3 was highly predictive of peanut allergy. Among individual components, only Ara h 2 was most correlated with severity of reaction at challenge and adrenaline use. Ara h 8 and 9 were not useful in predicting challenge outcome.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2021)

Add to Collection

Letter Allergy

Limited effect of intramuscular epinephrine on cardiovascular parameters during peanut-induced anaphylaxis: An observational cohort study

Paul J. Turner et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2021)

Add to Collection

Article Allergy

A Prospective Validation of the NUT CRACKER Diagnostic Algorithm for Walnut and Pecan Allergy with Prediction of Severity

Michael R. Goldberg et al.

Summary: The study validated a diagnostic algorithm to reduce the need for oral food challenges and predict the severity of walnut/pecan allergies using SPT and BAT. BAT is associated with the severity of walnut/pecan allergies, and the algorithm decreased the need for oral food challenges.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2021)

Add to Collection

Article Allergy

Delayed and Severe Reactions to Baked Egg and Baked Milk Challenges

Jennifer R. Yonkof et al.

Summary: This study compared the clinical features of reactions to baked egg and baked milk with other oral food challenges, showing differences in reaction phenotypes, including significantly increased frequencies of new symptoms beginning 60 minutes or later after challenge termination.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2021)

Add to Collection

Article Allergy

Peanut induced anaphylaxis in children and adolescents: Data from the European Anaphylaxis Registry

Ioana Maris et al.

Summary: The study showed that peanut allergy is a major cause of severe allergic reactions in European children, with characteristics such as asthma comorbidity and a higher rate of biphasic reactions. The use of intramuscular adrenaline as first-line treatment is low and needs improvement. The European Anaphylaxis Registry provides a valuable tool for continuous assessment of anaphylactic reactions.

ALLERGY (2021)

Add to Collection

Article Allergy

Using data from food challenges to inform management of consumers with food allergy: A systematic review with individual participant data meta-analysis

Nandinee Patel et al.

Summary: The study found that 5% of individuals with peanut allergy may develop anaphylaxis in response to exposure at ED01 or ED05 levels of peanut. Additionally, 2.4% of patients initially tolerating 5 mg of peanut protein developed reactions at subsequent challenge.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2021)

Add to Collection

Article Allergy

Retrospective analysis of 222 oral food challenges with a single dose in acute food protein-induced enterocolitis syndrome

Stefano Miceli Sopo et al.

Summary: The study suggests that administering a single dose in a full serving size for age is a safe and time-saving method for OFC in acute FPIES. For patients with positive SPT for the tested food, starting with a smaller dose may be prudent, with the option to move on to the full dose in the absence of adverse reactions.

PEDIATRIC ALLERGY AND IMMUNOLOGY (2021)

Add to Collection

Article Medicine, General & Internal

Food anaphylaxis in the United Kingdom: analysis of national data, 1998-2018

Alessia Baseggio Conrado et al.

Summary: The study revealed an increase in hospital admissions due to food-induced anaphylaxis in the UK from 1998 to 2018, with the largest increase observed in children under 15. The case fatality rate has decreased, however showing fluctuations, with cow's milk now being the most common single cause of fatal anaphylaxis in school aged children.

BMJ-BRITISH MEDICAL JOURNAL (2021)

Add to Collection

Article Allergy

Fruit-Induced Anaphylaxis: Clinical Presentation and Management

Sofianne Gabrielli et al.

Summary: This study analyzed 250 patients with fruit-induced anaphylaxis and found that severe reactions were more likely to occur in spring and among patients with eczema. Epinephrine use was low in the pre-hospital setting, with patients with moderate and severe reactions and known food allergies more likely to receive epinephrine treatment.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2021)

Add to Collection

Article Allergy

Differences in oral food challenge reaction severity based on increasing age in a pediatric population

Katie Kennedy et al.

Summary: Infants and young toddlers have milder reactions during oral food challenges compared to older age groups, with fewer symptoms involved in the reactions. Increasing age is significantly correlated with reaction severity.

ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2021)

Add to Collection

Article Chemistry, Applied

The impact of a baked muffin matrix on the bioaccessibility and IgE reactivity of egg and peanut allergens

Hadeer Mattar et al.

Summary: The study found that the bioaccessibility of egg and peanut allergens in muffins increased with duodenal digestion, with Gal d 2 and Ara h 2 showing high resistance to digestion. The IgE reactivity of bioaccessible peanut allergens was retained to a greater extent than that of egg allergens after oral-gastric digestion. The starch and gluten-rich muffin matrix modifies allergen bioaccessibility in a manner more similar to baked matrices such as bread.

FOOD CHEMISTRY (2021)

Add to Collection

Article Allergy

Global patterns in anaphylaxis due to specific foods: A systematic review

Alessia Baseggio Conrado et al.

Summary: A systematic review identified significant regional variations in common triggers for food-induced anaphylaxis, while also finding that local legislation for allergen disclosure generally corresponds to the common allergens responsible for food-induced anaphylaxis.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2021)

Add to Collection

Article Allergy

Wheat Anaphylaxis in Adults Differs from Reactions to Other Types of Food

Magdalena Kraft et al.

Summary: The study found that wheat is the most common food trigger of anaphylaxis in adults in Central Europe, often associated with cofactors such as exercise. Only 36.9% of patients with wheat anaphylaxis had atopic comorbidities, which is lower than for other food allergies. Wheat-induced anaphylaxis often presents with cardiovascular symptoms, suggesting the need for further research on mechanisms and preventive measures.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2021)

Add to Collection

Article Genetics & Heredity

Genome-wide association study reveals an association between the HLA-DPB1*02:01:02 allele and wheat-dependent exercise-induced anaphylaxis

Koya Fukunaga et al.

Summary: The study identified a significant association between the HLA-DPB1*02:01:02 allele and an increased risk of WDEIA. Individuals carrying this allele have a higher risk of developing WDEIA. Further validation in diverse populations is required.

AMERICAN JOURNAL OF HUMAN GENETICS (2021)

Add to Collection

Review Critical Care Medicine

Evidence update for the treatment of anaphylaxis

Amy Dodd et al.

Summary: The Resuscitation Council UK has updated its Guideline for healthcare providers on the Emergency treatment of anaphylaxis, with significant changes including repeating intramuscular adrenaline doses, no longer routinely recommending corticosteroids, interventions for refractory reactions, a recommendation against antihistamines, and guidance on observation duration and timing of discharge.

RESUSCITATION (2021)

Add to Collection

Article Allergy

Estimating the Risk of Severe Peanut Allergy Using Clinical Background and IgE Sensitization Profiles

Mareen R. Datema et al.

Summary: This study found that factors associated with severe PA included female sex, age at onset of PA, symptoms elicited by skin contact with peanut, while factors associated with mild-to-moderate PA included birch pollen allergy. Clinical background determinants were most valuable for predicting severity of probable PA in an individual patient.

FRONTIERS IN ALLERGY (2021)

Add to Collection

Article Allergy

Exercise-induced allergic reactions on desensitization to wheat after rush oral immunotherapy

Tomoko Furuta et al.

ALLERGY (2020)

Add to Collection

Article Allergy

Food aversion and poor weight gain in food protein-induced enterocolitis syndrome: A retrospective study

Kuan-Wen Su et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)

Add to Collection

Review Allergy

Anaphylaxis-a 2020 practice parameter update, systematic review, and Grading of Recommendations, Assessment, Development and Evaluation (GRADE) analysis

Marcus S. Shaker et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)

Add to Collection

Article Allergy

Clinical and Serological Characterization of the α-Gal Syndrome-Importance of Atopy for Symptom Severity in a European Cohort

M. B. Gea Kiewiet et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2020)

Add to Collection

Article Allergy

Biomarkers of severity and threshold of allergic reactions during oral peanut challenges

Alexandra F. Santos et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)

Add to Collection

Article Food Science & Technology

The Effect of the Food Matrix on the In Vitro Bio-Accessibility and IgE Reactivity of Peanut Allergens

Huan Rao et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2020)

Add to Collection

Article Allergy

Phenotyping peach-allergic patients sensitized to LTP and analysing severity biomarkers

Gador Bogas et al.

ALLERGY (2020)

Add to Collection

Article Allergy

EAACI Guideline on the effective transition of adolescents and young adults with allergy and asthma

Graham Roberts et al.

ALLERGY (2020)

Add to Collection

Article Allergy

Circulating Ara h 6 as a marker of peanut protein absorption in tolerant and allergic humans following ingestion of peanut-containing foods

Herve Bernard et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2020)

Add to Collection

Article Allergy

Risk Factors and Characteristics of Biphasic Anaphylaxis

Magdalena Kraft et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2020)

Add to Collection

Article Pediatrics

Risk Factors for Severe Anaphylaxis in Children

Mikel Olabarri et al.

JOURNAL OF PEDIATRICS (2020)

Add to Collection

Review Allergy

Can patients with oral allergy syndrome be at risk of anaphylaxis?

Isabel J. Skypala

CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY (2020)

Add to Collection

Article Public, Environmental & Occupational Health

Deaths, Hospitalizations, and Emergency Department Visits From Food-Related Anaphylaxis, New York City, 2000-2014: Implications for Fatality Prevention

Eugenie Poirot et al.

JOURNAL OF PUBLIC HEALTH MANAGEMENT AND PRACTICE (2020)

Add to Collection

Article Allergy

Wheat-Dependent Cofactor-Augmented Anaphylaxis: A Prospective Study of Exercise, Aspirin, and Alcohol Efficacy as Cofactors

Morten J. Christensen et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2019)

Add to Collection

Article Allergy

Potential cofactors in accidental food allergic reactions are frequently present but may not influence severity and occurrence

Astrid Versluis et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2019)

Add to Collection

Article Allergy

Allergen Recognition Patterns in Walnut Allergy Are Age Dependent and Correlate with the Severity of Allergic Reactions

Barbara K. Ballmer-Weber et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2019)

Add to Collection

Article Allergy

Factors predicting anaphylaxis in children with tree nut allergies

Pinar Gur Cetinkaya et al.

ALLERGY AND ASTHMA PROCEEDINGS (2019)

Add to Collection

Article Allergy

Epidemiology of Anaphylaxis in Critically III Children in the United States and Canada

Nicole B. Ramsey et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2019)

Add to Collection

Article Allergy

Evaluation of Prehospital Management in a Canadian Emergency Department Anaphylaxis Cohort

Sofianne Gabrielli et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2019)

Add to Collection

Article Allergy

Effect of sleep deprivation and exercise on reaction threshold in adults with peanut allergy: A randomized controlled study

Shelley Dua et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2019)

Add to Collection

Letter Allergy

Food-related anaphylaxis fatalities: Analysis of the Allergy Vigilance NetworkA® database

Guillaume Pouessel et al.

ALLERGY (2019)

Add to Collection

Article Immunology

Refractory Anaphylaxis: Data From the European Anaphylaxis Registry

Wojciech Francuzik et al.

FRONTIERS IN IMMUNOLOGY (2019)

Add to Collection

Article Allergy

Ratios of specific IgG4 over IgE antibodies do not improve prediction of peanut allergy nor of its severity compared to specific IgE alone

Mareen R. Datema et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2019)

Add to Collection

Article Allergy

Anaphylaxis admissions in pediatric intensive care units: Follow-up and risk of recurrence

Guillaume Pouessel et al.

PEDIATRIC ALLERGY AND IMMUNOLOGY (2019)

Add to Collection

Review Allergy

Relationship Between Anaphylaxis and Use of Beta-Blockers and Angiotensin-Converting Enzyme Inhibitors: A Systematic Review and Meta-Analysis of Observational Studies

Miguel A. Tejedor-Alonso et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2019)

Add to Collection

Editorial Material Allergy

A perspective on the pediatric death from oral food challenge reported from the Allergy Vigilance Network

Julia Upton et al.

ALLERGY (2019)

Add to Collection

Letter Allergy

Cosensitization to profilin is associated with less severe reactions to foods in nsLTPs and storage proteins reactors and with less severe respiratory allergy

E. Scala et al.

ALLERGY (2018)

Add to Collection

Review Allergy

How does dose impact on the severity of food-induced allergic reactions, and can this improve risk assessment for allergenic foods?: Report from an ILSI Europe Food Allergy Task Force Expert Group and Workshop

A. E. J. Dubois et al.

ALLERGY (2018)

Add to Collection

Article Allergy

Prediction of the severity of allergic reactions to foods

M. E. Pettersson et al.

ALLERGY (2018)

Add to Collection

Article Allergy

Factors increasing the risk for a severe reaction in anaphylaxis: An analysis of data from The European Anaphylaxis Registry

M. Worm et al.

ALLERGY (2018)

Add to Collection

Letter Allergy

Anaphylaxis admissions to pediatric intensive care units in France

G. Pouessel et al.

ALLERGY (2018)

Add to Collection

Article Allergy

Development of a tool predicting severity of allergic reaction during peanut challenge

R. Sharon Chinthrajah et al.

ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2018)

Add to Collection

Article Allergy

Predicting reactivity threshold in children with anaphylaxis to peanut

T. Reier-Nilsen et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2018)

Add to Collection

Article Allergy

Mast cell activation test in the diagnosis of allergic disease and anaphylaxis

Rajia Bahri et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2018)

Add to Collection

Article Allergy

Cow's milk allergic childrenCan component-resolved diagnostics predict duration and severity?

Thomas Houmann Petersen et al.

PEDIATRIC ALLERGY AND IMMUNOLOGY (2018)

Add to Collection

Article Allergy

Increasing specific immunoglobulin E levels correlate with the risk of anaphylaxis during an oral food challenge

Noriyuki Yanagida et al.

PEDIATRIC ALLERGY AND IMMUNOLOGY (2018)

Add to Collection

Article Allergy

Gal d 1-specific IgE predicts allergy to heated egg in Finnish children

Kati Palosuo et al.

PEDIATRIC ALLERGY AND IMMUNOLOGY (2018)

Add to Collection

Article Allergy

Severity and threshold of peanut reactivity during hospital-based open oral food challenges: An international multicenter survey

Peter D. Arkwright et al.

PEDIATRIC ALLERGY AND IMMUNOLOGY (2018)

Add to Collection

Article Allergy

A Multicenter Evaluation of Diagnosis and Management of Omega-5 Gliadin Allergy (Also Known as Wheat-Dependent Exercise-Induced Anaphylaxis) in 132 Adults

Lucinda Kennard et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2018)

Add to Collection

Article Allergy

Diagnostic Value of Tryptase in Food Allergic Reactions: A Prospective Study of 160 Adult Peanut Challenges

Shelley Dua et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2018)

Add to Collection

Article Allergy

Exercise Lowers Threshold and Increases Severity, but Wheat-Dependent, Exercise-Induced Anaphylaxis Can Be Elicited at Rest

Morten J. Christensen et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2018)

Add to Collection

Article Immunology

Eliciting Dose and Safety Outcomes From a Large Dataset of Standardized Multiple Food Challenges

Natasha Purington et al.

FRONTIERS IN IMMUNOLOGY (2018)

Add to Collection

Article Allergy

Component-resolved diagnosis and beyond: Multivariable regression models to predict severity of hazelnut allergy

M. R. Datema et al.

ALLERGY (2018)

Add to Collection

Editorial Material Allergy

Crossing the threshold: can outcome data from food challenges be used to predict risk of anaphylaxis in the community?

P. J. Turner et al.

ALLERGY (2017)

Add to Collection

Article Allergy

Risk Factors for Severe Reactions during Double-Blind Placebo-Controlled Food Challenges

Noriyuki Yanagida et al.

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY (2017)

Add to Collection

Article Allergy

Clinical Profile of Patients With Severe Anaphylaxis Hospitalized in the Spanish Hospital System: 1997-2011

A. Nieto-Nieto et al.

JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY (2017)

Add to Collection

Article Allergy

Food Challenge and Community-Reported Reaction Profiles in Food-Allergic Children Aged 1 and 4 Years: A Population-Based Study

Joshua C. K. Chan et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2017)

Add to Collection

Article Allergy

Risk factors for severe anaphylaxis in the United States

Megan S. Motosue et al.

ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2017)

Add to Collection

Article Allergy

Oral food challenge outcomes in a pediatric tertiary care center

Elissa M. Abrams et al.

ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY (2017)

Add to Collection

Review Allergy

Can we identify patients at risk of life-threatening allergic reactions to food?

P. J. Turner et al.

ALLERGY (2016)

Add to Collection

Article Allergy

Peanut-allergic patients in the MIRABEL survey: characteristics, allergists' dietary advice and lessons from real life

A. Deschildre et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2016)

Add to Collection

Article Allergy

Increases in anaphylaxis fatalities in Australia from 1997 to 2013

R. J. Mullins et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2016)

Add to Collection

Meeting Abstract Allergy

Increase in Intensive Care Unit Admissions for Anaphylaxis in the United Kingdom 2008-2012

Deepan Vyas et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)

Add to Collection

Article Allergy

Tryptase levels in children presenting with anaphylaxis: Temporal trends and associated factors

Sarah De Schryver et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)

Add to Collection

Article Allergy

Anaphylaxis in children and adolescents: The European Anaphylaxis Registry

Linus B. Grabenhenrich et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)

Add to Collection

Article Allergy

Characteristics of Anaphylaxis in 907 Chinese Patients Referred to a Tertiary Allergy Center: A Retrospective Study of 1,952 Episodes

Nannan Jiang et al.

ALLERGY ASTHMA & IMMUNOLOGY RESEARCH (2016)

Add to Collection

Article Allergy

The Emperor Has No Symptoms: The Risks of a Blanket Approach to Using Epinephrine Autoinjectors for All Allergic Reactions

Paul J. Turner et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2016)

Add to Collection

Article Immunology

Cofactors in allergic reactions to food: physical exercise and alcohol are the most important

Astrid Versluis et al.

IMMUNITY INFLAMMATION AND DISEASE (2016)

Add to Collection

Article Allergy

Ara h 2 and Ara 6 are the best predictors of severe peanut allergy: a double-blind placebo-controlled study

A. K. Kukkonen et al.

ALLERGY (2015)

Add to Collection

Article Allergy

IgE recognition patterns in peanut allergy are age dependent: perspectives of the EuroPrevall study

B. K. Ballmer-Weber et al.

ALLERGY (2015)

Add to Collection

Article Allergy

Correlations between basophil activation, allergen-specific IgE with outcome and severity of oral food challenges

Ying Song et al.

ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2015)

Add to Collection

Review Food Science & Technology

Food processing and allergenicity

Kitty C. M. Verhoeckx et al.

FOOD AND CHEMICAL TOXICOLOGY (2015)

Add to Collection

Letter Allergy

Impact of sex on anaphylaxis severity-data from the Anaphylaxis Registry

Wojciech Francuzik et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2015)

Add to Collection

Article Allergy

Ramipril and metoprolol intake aggravate human and murine anaphylaxis: Evidence for direct mast cell priming

Maria Nassiri et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2015)

Add to Collection

Article Allergy

Increase in anaphylaxis-related hospitalizations but no increase in fatalities: An analysis of United Kingdom national anaphylaxis data, 1992-2012

Paul J. Turner et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2015)

Add to Collection

Article Allergy

How much is too much? Threshold dose distributions for 5 food allergens

Barbara K. Ballmer-Weber et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2015)

Add to Collection

Review Allergy

Time of Onset and Predictors of Biphasic Anaphylactic Reactions: A Systematic Review and Meta-analysis

Sangil Lee et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2015)

Add to Collection

Review Allergy

Risk multipliers for severe food anaphylaxis

Peter K. Smith et al.

WORLD ALLERGY ORGANIZATION JOURNAL (2015)

Add to Collection

Review Pediatrics

Ten-year review reveals changing trends and severity of allergic reactions to nuts and other foods

Jennifer Johnson et al.

ACTA PAEDIATRICA (2014)

Add to Collection

Article Allergy

Serum basal tryptase may be a good marker for predicting the risk of anaphylaxis in children with food allergy

U. M. Sahiner et al.

ALLERGY (2014)

Add to Collection

Article Allergy

Recurrent reactions to food among children at paediatric emergency departments

M. Vetander et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2014)

Add to Collection

Editorial Material Allergy

A food allergy syndrome by any other name?

P. J. Turner et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2014)

Add to Collection

Article Allergy

Hazelnut allergy differs between children and adults in frequency of severity, aetiology and relevance of diagnostic parameters

L. J. Masthoff et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2014)

Add to Collection

Article Allergy

Risk factors for severe anaphylaxis in patients receiving anaphylaxis treatment in US emergency departments and hospitals

Sunday Clark et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2014)

Add to Collection

Article Allergy

Fatal anaphylaxis in the United States, 1999-2010: Temporal patterns and demographic associations

Elina Jerschow et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2014)

Add to Collection

Article Allergy

Anaphylaxis-related deaths in Ontario: a retrospective review of cases from 1986 to 2011

Ya Sophia Xu et al.

ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY (2014)

Add to Collection

Article Allergy

Clinical value of component-resolved diagnostics in peanut-allergic patients

E. Eller et al.

ALLERGY (2013)

Add to Collection

Review Allergy

Incidence of fatal food anaphylaxis in people with food allergy: a systematic review and meta-analysis

T. Umasunthar et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2013)

Add to Collection

Article Allergy

No matrix effect in double-blind, placebo-controlled egg challenges in egg allergic children

L. Libbers et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2013)

Add to Collection

Article Allergy

Sensitization to Cor a 9 and Cor a 14 is highly specific for a hazelnut allergy with objective symptoms in Dutch children and adults

Laury J. N. Masthoff et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2013)

Add to Collection

Article Allergy

Anaphylaxis: Clinical patterns, mediator release, and severity

Simon G. A. Brown et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2013)

Add to Collection

Review Allergy

Why do few food-allergic adolescents treat anaphylaxis with adrenaline? reviewing a pressing issue

Tom Marrs et al.

PEDIATRIC ALLERGY AND IMMUNOLOGY (2013)

Add to Collection

Article Allergy

Can we predict severe reactions during peanut challenges in children?

Francine C. van Erp et al.

PEDIATRIC ALLERGY AND IMMUNOLOGY (2013)

Add to Collection

Article Medicine, General & Internal

Concomitant chronic pulmonary diseases and their association with hospital outcomes in patients with anaphylaxis and other allergic conditions: a cohort study

Zuber D. Mulla et al.

BMJ OPEN (2013)

Add to Collection

Article Allergy

Ara h 2 Is the Best Predictor for Peanut Allergy in Adults

Rob J. B. Klemans et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2013)

Add to Collection

Article Allergy

Outcome of oral food challenges in children in relation to symptom-eliciting allergen dose and allergen-specific IgE

C. Rolinck-Werninghaus et al.

ALLERGY (2012)

Add to Collection

Article Allergy

Clinical thresholds to egg, hazelnut, milk and peanut: results from a single-center study using standardized challenges

Esben Eller et al.

ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2012)

Add to Collection

Article Allergy

The natural history of persistent peanut allergy

Dara L. Neuman-Sunshine et al.

ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2012)

Add to Collection

Article Allergy

Anaphylaxis and reactions to foods in children - a population-based case study of emergency department visits

M. Vetander et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2012)

Add to Collection

Article Allergy

Increasing the accuracy of peanut allergy diagnosis by using Ara h 2

Thanh D. Dang et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2012)

Add to Collection

Article Allergy

Anaphylaxis in a New York City pediatric emergency department: Triggers, treatments, and outcomes

Faith Huang et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2012)

Add to Collection

Article Food Science & Technology

High fat food increases gastric residence and thus thresholds for objective symptoms in allergic patients

Alan Mackie et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2012)

Add to Collection

Article Allergy

Inadvertent exposures in children with peanut allergy

Nha Uyen Nguyen-Luu et al.

PEDIATRIC ALLERGY AND IMMUNOLOGY (2012)

Add to Collection

Review Allergy

Gut permeability and food allergies

C. Perrier et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2011)

Add to Collection

Article Allergy

Efficacy and safety of high-dose peanut oral immunotherapy with factors predicting outcome

K. Anagnostou et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2011)

Add to Collection

Article Allergy

Pru p 3-Sensitised Italian Peach-Allergic Patients Are Less Likely to Develop Severe Symptoms When Also Presenting IgE Antibodies to Pru p 1 and Pru p 4

Elide A. Pastorello et al.

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY (2011)

Add to Collection

Article Allergy

Risk factors for severe pediatric food anaphylaxis in Italy

Mauro Calvani et al.

PEDIATRIC ALLERGY AND IMMUNOLOGY (2011)

Add to Collection

Article Allergy

How do teenagers manage their food allergies?

H. Monks et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2010)

Add to Collection

Article Food Science & Technology

Threshold dose for peanut: Risk characterization based upon diagnostic oral challenge of a series of 286 peanut-allergic individuals

Steve L. Taylor et al.

FOOD AND CHEMICAL TOXICOLOGY (2010)

Add to Collection

Letter Allergy

Trends in pediatric emergency department visits for food-induced anaphylaxis

Susan A. Rudders et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2010)

Add to Collection

Article Allergy

Correlation of IgE/IgG4 milk epitopes and affinity of milk-specific IgE antibodies with different phenotypes of clinical milk allergy

Julie Wang et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2010)

Add to Collection

Article Allergy

Prediction of anaphylaxis during peanut food challenge: usefulness of the peanut skin prick test (SPT) and specific IgE level

Brynn Kevin Wainstein et al.

PEDIATRIC ALLERGY AND IMMUNOLOGY (2010)

Add to Collection

Article Allergy

How much specific is the association between hymenoptera venom allergy and mastocytosis?

P. Bonadonna et al.

ALLERGY (2009)

Add to Collection

Letter Allergy

Adverse reactions during peanut oral immunotherapy home dosing

Pooja Varshney et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2009)

Add to Collection

Article Allergy

Good prognosis, clinical features, and circumstances of peanut and tree nut reactions in children treated by a specialist allergy center

Andrew T. Clark et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2008)

Add to Collection

Article Allergy

Peanut epitopes for IgE and IgG4 in peanut-sensitized children in relation to severity of peanut allergy

Annebeth E. Flinterman et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2008)

Add to Collection

Article Allergy

Factors predicting anaphylaxis to peanuts and tree nuts in patients referred to a specialist center

Colin W. Summers et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2008)

Add to Collection

Article Allergy

Tolerance to extensively heated milk in children with cow's milk allergy

Anna Nowak-Wegrzyn et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2008)

Add to Collection

Article Allergy

IgG and IgE avidity characteristics of peanut allergic individuals

Fatima El-Khouly et al.

PEDIATRIC ALLERGY AND IMMUNOLOGY (2007)

Add to Collection

Letter Allergy

Further fatal allergic reactions to food in the United Kingdom, 1999-2006

Richard S. H. Pumphrey et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2007)

Add to Collection

Letter Allergy

Further fatalities caused by anaphylactic reactions to food, 2001-2006

S. Allan Bock et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2007)

Add to Collection

Article Allergy

Exercise and aspirin increase levels of circulating gliadin peptides in patients with wheat-dependent exercise-induced anaphylaxis

H Matsuo et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2005)

Add to Collection

Article Allergy

Microarray immunoassay: Association of clinical history, in vitro IgE function, and heterogeneity of allergenic peanut epitopes

WG Shreffler et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2004)

Add to Collection

Article Allergy

Presentation of allergen in different food preparations affects the nature of the allergic reaction - a case series

KEC Grimshaw et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2003)

Add to Collection

Article Allergy

Fatalities due to anaphylactic reactions to foods

SA Bock et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2001)

Add to Collection

Risk factors for severe reactions in food allergy: Rapid evidence review with meta-analysis

Related references

Export Citation

Share Paper