4.8 Article

Systematic Screening and Therapeutic Evaluation of Glyconanoparticles with Differential Cancer Affinities for Targeted Cancer Therapy

Related references

Note: Only part of the references are listed.
Article Biochemical Research Methods

The Complexity and Dynamics of the Tissue Glycoproteome Associated With Prostate Cancer Progression

Rebeca Kawahara et al.

Summary: The study utilizes glycomics and glycoproteomics to reveal unique N- and O-glycosylation features in prostate cancer (PCa) tissues, identifying their association with PCa progression. This provides new insights into the complexity and dynamics of the tissue glycoproteome associated with PCa progression, serving as an important resource for exploring the underlying disease mechanisms.

MOLECULAR & CELLULAR PROTEOMICS (2021)

Article Biotechnology & Applied Microbiology

Fusogenic oncolytic vaccinia virus enhances systemic antitumor immune response by modulating the tumor microenvironment

Motomu Nakatake et al.

Summary: The novel fusogenic oncolytic vaccinia virus (FUVAC) showed enhanced cytopathic effects and immunogenic cell death in cancer cells compared to its nonfusogenic parent virus. FUVAC not only inhibited tumor growth in both treated and untreated tumors in mice, but also improved the tumor immune microenvironment, leading to systemic antitumor immunity. Administering FUVAC before immune checkpoint inhibitor (ICI) treatment resulted in complete responses in both treated and untreated tumors, establishing a long-term tumor-specific immune memory.

MOLECULAR THERAPY (2021)

Article Biochemistry & Molecular Biology

Induction of Apoptotic Temperature in Photothermal Therapy under Various Heating Conditions in Multi-Layered Skin Structure

Donghyuk Kim et al.

Summary: This study conducted numerical analysis to induce apoptosis of tumor tissue under various heating conditions in photothermal therapy. Results showed a quantitative correlation between laser intensity, volume fraction of gold nanorods injected into the tumor, and cooling time with the effective apoptosis retention ratio. This research reveals optimal conditions for maximizing apoptosis within tumor tissue while minimizing thermal damage to surrounding tissues under different heating conditions.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Review Engineering, Biomedical

The evolution of commercial drug delivery technologies

Ava M. Vargason et al.

Summary: This review article discusses how challenges in delivering small molecules, nucleic acids, peptides, proteins, and cells have led to the development of commercial products and are now guiding the delivery of live-cell therapeutics. Drug delivery technologies have enabled the development of pharmaceutical products that enhance therapeutic delivery, minimize off-target effects, and improve patient compliance. Three drug delivery paradigms have been developed to aid in the successful delivery of small molecules and macromolecules, contributing to the initial clinical success of each therapeutic class.

NATURE BIOMEDICAL ENGINEERING (2021)

Article Engineering, Biomedical

Nanoparticle-mediated convection-enhanced delivery of a DNA intercalator to gliomas circumvents temozolomide resistance

Yongheng Wang et al.

Summary: Nanoparticles releasing an oxaliplatin prodrug and a cationic DNA intercalator within temozolomide-resistant gliomas inhibit tumor growth without causing detectable toxicity. Combining anticancer drugs with distinct mechanisms of action, selective drug release, and convection-enhanced delivery may represent a translational strategy for the treatment of TMZ-resistant gliomas.

NATURE BIOMEDICAL ENGINEERING (2021)

Review Oncology

Glycosylation and raft endocytosis in cancer

Ludger Johannes et al.

CANCER AND METASTASIS REVIEWS (2020)

Review Oncology

Glycosylated Nanoparticles for Cancer-Targeted Drug Delivery

Sergio Andres Torres-Perez et al.

FRONTIERS IN ONCOLOGY (2020)

Review Pharmacology & Pharmacy

Towards more accurate bioimaging of drug nanocarriers: turning aggregation-caused quenching into a useful tool

Jianping Qi et al.

ADVANCED DRUG DELIVERY REVIEWS (2019)

Review Pharmacology & Pharmacy

Hyaluronic Acid-Coated Nanomedicine for Targeted Cancer Therapy

Kibeom Kim et al.

PHARMACEUTICS (2019)

Review Chemistry, Multidisciplinary

Organic molecule-based photothermal agents: an expanding photothermal therapy universe

Hyo Sung Jung et al.

CHEMICAL SOCIETY REVIEWS (2018)

Review Physics, Multidisciplinary

Physical biology of the cancer cell glycocalyx

Joe Chin-Hun Kuo et al.

NATURE PHYSICS (2018)

Article Medicine, Research & Experimental

Photo-decomposable Organic Nanoparticles for Combined Tumor Optical Imaging and Multiple Phototherapies

Wenjun Miao et al.

THERANOSTICS (2016)

Review Oncology

Glycosylation in cancer: mechanisms and clinical implications

Salome S. Pinho et al.

NATURE REVIEWS CANCER (2015)

Article Chemistry, Multidisciplinary

Synthesis and therapeutic evaluation of an aptide-docetaxel conjugate targeting tumor-associated fibronectin

Hyungjun Kim et al.

JOURNAL OF CONTROLLED RELEASE (2014)

Article Multidisciplinary Sciences

The cancer glycocalyx mechanically primes integrin-mediated growth and survival

Matthew J. Paszek et al.

NATURE (2014)

Article Multidisciplinary Sciences

Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates

Yizhou Dong et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Chemistry, Multidisciplinary

'Multicopy Multivalent' Glycopolymer-Stabilized Gold Nanoparticles as Potential Synthetic Cancer Vaccines

Alison L. Parry et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

Editorial Material Biotechnology & Applied Microbiology

Antibody-drug conjugates

Rachel S. Zolot et al.

NATURE REVIEWS DRUG DISCOVERY (2013)

Article Biochemistry & Molecular Biology

Carbohydrate to carbohydrate interaction in development process and cancer progression

Kazuko Handa et al.

GLYCOCONJUGATE JOURNAL (2012)

Review Oncology

Treating metastatic cancer with nanotechnology

Avi Schroeder et al.

NATURE REVIEWS CANCER (2012)

Review Pharmacology & Pharmacy

Tumor delivery of macromolecular drugs based on the EPR effect

Vladimir Torchilin

ADVANCED DRUG DELIVERY REVIEWS (2011)

Article Biochemistry & Molecular Biology

Differential Carbohydrate Binding and Cell Surface Glycosylation of Human Cancer Cell Lines

Nadia X. Arndt et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2011)

Article Computer Science, Interdisciplinary Applications

PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel

Yong Zhang et al.

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE (2010)

Article Chemistry, Multidisciplinary

Magnetic Glyco-Nanoparticles: A Tool To Detect, Differentiate, and Unlock the Glyco-Codes of Cancer via Magnetic Resonance Imaging

Kheireddine El-Boubbou et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

Article Chemistry, Multidisciplinary

Small-Molecule End-Groups of Linear Polymer Determine Cell-Type Gene-Delivery Efficacy

Joel Sunshine et al.

ADVANCED MATERIALS (2009)

Review Engineering, Biomedical

Reduction-sensitive polymers and bioconjugates for biomedical applications

Fenghua Meng et al.

BIOMATERIALS (2009)

Article Biochemistry & Molecular Biology

Exploring the structural diversity of mammalian carbohydrates (Glycospace) by statistical databank analysis

Daniel B. Werz et al.

ACS CHEMICAL BIOLOGY (2007)

Article Biotechnology & Applied Microbiology

Exploiting lymphatic transport and complement activation in nanoparticle vaccines

Sai T. Reddy et al.

NATURE BIOTECHNOLOGY (2007)

Article Multidisciplinary Sciences

Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo

OC Farokhzad et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Pharmacology & Pharmacy

Drug targeting to the colon with lectins and neoglycoconjugates

T Minko

ADVANCED DRUG DELIVERY REVIEWS (2004)

Article Pharmacology & Pharmacy

Clinical pharmacokinetics of unbound docetaxel: Role of polysorbate 80 and serum proteins

WJ Loos et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2003)

Review Pharmacology & Pharmacy

Pharmacological effects of formulation vehicles - Implications for cancer chemotherapy

AJ ten Tije et al.

CLINICAL PHARMACOKINETICS (2003)

Review Biochemistry & Molecular Biology

Carbohydrate-binding proteins in cancer, and their ligands as therapeutic agents

P Nangia-Makker et al.

TRENDS IN MOLECULAR MEDICINE (2002)