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Local scaffold-assisted delivery of immunotherapeutic agents for improved cancer immunotherapy

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Qian Chen et al.

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Red blood cell-derived nanoerythrosome for antigen delivery with enhanced cancer immunotherapy

Xiao Han et al.

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Cytokines in clinical cancer immunotherapy

Pedro Berraondo et al.

BRITISH JOURNAL OF CANCER (2019)

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In situ thermal ablation of tumors in combination with nano-adjuvant and immune checkpoint blockade to inhibit cancer metastasis and recurrence

Xiao Han et al.

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In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment

Qian Chen et al.

NATURE NANOTECHNOLOGY (2019)

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Delivery technologies for cancer immunotherapy

Rachel S. Riley et al.

NATURE REVIEWS DRUG DISCOVERY (2019)

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Emerging Nano-/Microapproaches for Cancer Immunotherapy

Yu Mi et al.

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Tumor Microenvironment-Activatable Prodrug Vesicles for Nanoenabled Cancer Chemoimmunotherapy Combining Immunogenic Cell Death Induction and CD47 Blockade

Fangyuan Zhou et al.

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A Dual-Bioresponsive Drug-Delivery Depot for Combination of Epigenetic Modulation and Immune Checkpoint Blockade

Huitong Ruan et al.

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Immune targets in the tumor microenvironment treated by radiotherapy

Omer M. Ozpiskin et al.

THERANOSTICS (2019)

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Injectable polypeptide hydrogel-based co-delivery of vaccine and immune checkpoint inhibitors improves tumor immunotherapy

Huijuan Song et al.

THERANOSTICS (2019)

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Injectable Bioresponsive Gel Depot for Enhanced Immune Checkpoint Blockade

Shuangjiang Yu et al.

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STINGel: Controlled release of a cyclic dinucleotide for enhanced cancer immunotherapy.

David G. Leach et al.

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Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity

Logan K. Smith et al.

IMMUNITY (2018)

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Hyaluronic acid based low viscosity hydrogel as a novel carrier for Convection Enhanced Delivery of CAR T cells

Ahmet F. Atik et al.

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Engineering a designer immunotherapy Tailoring cytokine selectivity by engineering receptor-ligand pairs circumvents toxicity

Crystal L. Mackall

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Cancer immunotherapy using checkpoint blockade

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Extended release of perioperative immunotherapy prevents tumor recurrence and eliminates metastases

Chun Gwon Park et al.

SCIENCE TRANSLATIONAL MEDICINE (2018)

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In situ formed reactive oxygen species-responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy

Chao Wang et al.

SCIENCE TRANSLATIONAL MEDICINE (2018)

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Injectable, Tough Alginate Cryogels as Cancer Vaccines

Ting-Yu Shih et al.

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Elimination of established tumors with nanodisc-based combination chemoimmunotherapy

Rui Kuai et al.

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Combined local immunostimulatory radioisotope therapy and systemic immune checkpoint blockade imparts potent antitumour responses

Yu Chao et al.

NATURE BIOMEDICAL ENGINEERING (2018)

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Toward Biomaterials for Enhancing Immune Checkpoint Blockade Therapy

Qin Fan et al.

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Binary Cooperative Prodrug Nanoparticles Improve Immunotherapy by Synergistically Modulating Immune Tumor Microenvironment

Bing Feng et al.

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CD47 Blockade by Hu5F9-G4 and Rituximab in Non-Hodgkin's Lymphoma

Ranjana Advani et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

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DOX/IL-2/IFN-γ co-loaded thermo-sensitive polypeptide hydrogel for efficient melanoma treatment

Qiang Lv et al.

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Inflammatory breast cancer biology: the tumour microenvironment is key

Bora Lim et al.

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TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Antitumor Activity and Minimal Erythrocyte Binding

Penka S. Petrova et al.

CLINICAL CANCER RESEARCH (2017)

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Designer vaccine nanodiscs for personalized cancer immunotherapy

Rui Kuai et al.

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A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer

Chiara Berlato et al.

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Interleukin-15 and cisplatin co-encapsulated thermosensitive polypeptide hydrogels for combined immuno-chemotherapy

Xilong Wu et al.

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Replication Study: The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

Stephen K. Horrigan

ELIFE (2017)

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Drug-eluting scaffold inhibited in vivo pancreatic tumorigenesis by engaging murine CCR4(+)CD8(+) T cells

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COLLOIDS AND SURFACES B-BIOINTERFACES (2017)

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Pulmonary Toxicities from Checkpoint Immunotherapy for Malignancy

Jennifer D. Possick

CLINICS IN CHEST MEDICINE (2017)

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Growth inhibitory effect of an injectable hyaluronic acid-tyramine hydrogels incorporating human natural interferon-alpha and sorafenib on renal cell carcinoma cells

Kosuke Ueda et al.

ACTA BIOMATERIALIA (2016)

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The effect of surface modification of mesoporous silica micro-rod scaffold on immune cell activation and infiltration

Weiwei Aileen Li et al.

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Direct activation of STING in the tumor microenvironment leads to potent and systemic tumor regression and immunity

Laura Hix Glickman et al.

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Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade

Joseph L. Benci et al.

CELL (2016)

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Enhanced Cancer Immunotherapy by Microneedle Patch-Assisted Delivery of Anti-PD1 Antibody

Chao Wang et al.

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The role of microglia and macrophages in glioma maintenance and progression

Dolores Hambardzumyan et al.

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Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy

Christine E. Brown et al.

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Anti-PD-1 antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM

Dimitrios Mathios et al.

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Antitumour actions of interferons: implications for cancer therapy

Belinda S. Parker et al.

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Polymeric microparticles for sustained and local delivery of antiCD40 and antiCTLA-4 in immunotherapy of cancer

Sima Rahimian et al.

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Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy

Suzanne L. Topalian et al.

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Injectable cryogel-based whole-cell cancer vaccines

Sidi A. Bencherif et al.

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A Perspective on the Clinical Translation of Scaffolds for Tissue Engineering

Matthew J. Webber et al.

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Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy

Jaeyun Kim et al.

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Type I interferons in anticancer immunity

Laurence Zitvogel et al.

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High dose interleukin-2 (Aldesleukin) - expert consensus on best management practices-2014

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Oncology Meets Immunology: The Cancer-Immunity Cycle

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Injectable hyaluronic acid-tyramine hydrogels incorporating interferon-α2a for liver cancer therapy

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Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

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Cancer Immunotherapy

Jennifer Couzin-Frankel

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Highly stretchable and tough hydrogels

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Injectable preformed scaffolds with shape-memory properties

Sidi A. Bencherif et al.

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Interleukin-15 biology and its therapeutic implications in cancer

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Cancer immunotherapy via dendritic cells

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Type I interferon is selectively required by dendritic cells for immune rejection of tumors

Mark S. Diamond et al.

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Cancer immunotherapy comes of age

Ira Mellman et al.

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Immune parameters affecting the efficacy of chemotherapeutic regimens

Laurence Zitvogel et al.

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Cytokines and the inception of CD8 T cell responses

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Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblastoma multiforme

Matthew J. McGirt et al.

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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

Hiroki Ishikawa et al.

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Use of Gliadel (BCNU) wafer in the surgical treatment of malignant glioma: A 10-year institutional experience

Frank J. Attenello et al.

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Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response

Keiichi Koizumi et al.

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The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design

Thomas A. Waldmann

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Viruses and interferon: A fight for supremacy

MG Katze et al.

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Interleukin-2 and interleukin-15: immunotherapy for cancer

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