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Liuxiang Chu et al.
DRUG DELIVERY (2018)
Cancer Vaccine Immunotherapy with RNA-Loaded Liposomes
Elias J. Sayour et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Glioblastoma Chemoresistance: The Double Play by Microenvironment and Blood-Brain Barrier
Martina Da Ros et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Peptide-Functionalized Nanoinhibitor Restrains Brain Tumor Growth by Abrogating Mesenchymal-Epithelial Transition Factor (MET) Signaling
Yingwei Wu et al.
NANO LETTERS (2018)
Apolipoprotein E Peptide-Directed Chimeric Polymersomes Mediate an Ultrahigh-Efficiency Targeted Protein Therapy for Glioblastoma
Yu Jiang et al.
ACS NANO (2018)
Intranasal Perillyl Alcohol for Glioma Therapy: Molecular Mechanisms and Clinical Development
Thomas C. Chen et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Developments in Blood-Brain Barrier Penetrance and Drug Repurposing for Improved Treatment of Glioblastoma
Bryan G. Harder et al.
FRONTIERS IN ONCOLOGY (2018)
Contributions of immune cell populations in the maintenance, progression, and therapeutic modalities of glioma
Michael D. Caponegro et al.
AIMS ALLERGY AND IMMUNOLOGY (2018)
Lipid metabolism reprogramming and its potential targets in cancer
Chunming Cheng et al.
CANCER COMMUNICATIONS (2018)
Drug-Target Kinetics in Drug Discovery
Peter J. Tonge
ACS CHEMICAL NEUROSCIENCE (2018)
Brain tumour post-treatment imaging and treatment-related complications
Alexander T. Kessler et al.
INSIGHTS INTO IMAGING (2018)
Canine brain tumours: a model for the human disease?
J. Hicks et al.
VETERINARY AND COMPARATIVE ONCOLOGY (2017)
Quantitative Fluorescence Microscopy Measures Vascular Pore Size in Primary and Metastatic Brain Tumors
Rajendar K. Mittapalli et al.
CANCER RESEARCH (2017)
Inter-heterogeneity and intra-heterogeneity of αvβ3 in non-small cell lung cancer and small cell lung cancer patients as revealed by 68Ga-RGD2 PET imaging
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EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2017)
Novel CNS drug discovery and development approach: model-based integration to predict neuro-pharmacokinetics and pharmacodynamics
Elizabeth C. M. de lange et al.
EXPERT OPINION ON DRUG DISCOVERY (2017)
Biomimetics in drug delivery systems: A critical review
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JOURNAL OF CONTROLLED RELEASE (2017)
cRGD peptide-installed epirubicin-loaded polymeric micelles for effective targeted therapy against brain tumors
S. Quader et al.
JOURNAL OF CONTROLLED RELEASE (2017)
RNA interference for glioblastoma therapy: Innovation ladder from the bench to clinical trials
Eunice L. Lozada-Delgado et al.
LIFE SCIENCES (2017)
Immunosuppressive Myeloid Cells' Blockade in the Glioma Microenvironment Enhances the Efficacy of Immune-Stimulatory Gene Therapy
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MOLECULAR THERAPY (2017)
Nanomaterial-Enabled Cancer Therapy
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MOLECULAR THERAPY (2017)
Neutrophil-mediated anticancer drug delivery for suppression of postoperative malignant glioma recurrence
Jingwei Xue et al.
NATURE NANOTECHNOLOGY (2017)
Therapeutic Hypothesis Testing With Rodent Brain Tumor Models
Derek A. Wainwright et al.
NEUROTHERAPEUTICS (2017)
Glioblastoma stem cells exploit the αvβ8 integrin-TGFβ1 signaling axis to drive tumor initiation and progression
P. A. Guerrero et al.
ONCOGENE (2017)
Vascular Mimicry: A Novel Neovascularization Mechanism Driving Anti-Angiogenic Therapy (AAT) Resistance in Glioblastoma
Kartik Angara et al.
TRANSLATIONAL ONCOLOGY (2017)
Interest of integrins targeting in glioblastoma according to tumor heterogeneity and cancer stem cell paradigm: an update
Laure Malric et al.
ONCOTARGET (2017)
The potential roles of aquaporin 4 in malignant gliomas
Yu-Long Lan et al.
Oncotarget (2017)
PTEN Regulates Glucose Transporter Recycling by Impairing SNX27 Retromer Assembly
Swapnil Rohidas Shinde et al.
CELL REPORTS (2017)
472PPHASE 1/2A STUDY OF GLUTATHIONE PEGYLATED LIPOSOMAL DOXORUBICIN (2B3-101) IN PATIENTS WITH BRAIN METASTASES (BM) FROM SOLID TUMORS OR RECURRENT HIGH GRADE GLIOMAS (HGG)
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ANNALS OF ONCOLOGY (2017)
A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins
Tobias G. Kapp et al.
SCIENTIFIC REPORTS (2017)
Sensitization of glioblastoma tumor micro-environment to chemo- and immunotherapy by Galectin-1 intranasal knock-down strategy
Matthias Van Woensel et al.
SCIENTIFIC REPORTS (2017)
Dynamics of nanoparticle diffusion and uptake in three-dimensional cell cultures
Valentina Belli et al.
COLLOIDS AND SURFACES B-BIOINTERFACES (2017)
Tumour acidosis: from the passenger to the driver's seat
Cyril Corbet et al.
NATURE REVIEWS CANCER (2017)
Glioblastoma stem-like cells secrete the pro-angiogenic VEGF-A factor in extracellular vesicles
Lucas Treps et al.
JOURNAL OF EXTRACELLULAR VESICLES (2017)
The acidic microenvironment as a possible niche of dormant tumor cells
Silvia Peppicelli et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2017)
Bevacizumab for malignant gliomas: current indications, mechanisms of action and resistance, and markers of response
Ryota Tamura et al.
BRAIN TUMOR PATHOLOGY (2017)
Critical review of the addition of tumor treating fields (TTFields) to the existing standard of care for newly diagnosed glioblastoma patients
M. Mehta et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2017)
Glioma: experimental models and reality
Krissie Lenting et al.
ACTA NEUROPATHOLOGICA (2017)
Immunogenic cell death in cancer and infectious disease
Lorenzo Galluzzi et al.
NATURE REVIEWS IMMUNOLOGY (2017)
Challenges and strategies in anti-cancer nanomedicine development: An industry perspective
Jennifer I. Hare et al.
ADVANCED DRUG DELIVERY REVIEWS (2017)
Kinase inhibitors and monoclonal antibodies in oncology: clinical implications
Helen Gharwan et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2016)
The drug-target residence time model: a 10-year retrospective
Robert A. Copeland
NATURE REVIEWS DRUG DISCOVERY (2016)
Years of potential life lost for brain and CNS tumors relative to other cancers in adults in the United States, 2010
Chaturia Rouse et al.
NEURO-ONCOLOGY (2016)
PD-L1 expression and prognostic impact in glioblastoma
Edjah K. Nduom et al.
NEURO-ONCOLOGY (2016)
T7 Peptide-Functionalized PEG-PLGA Micelles Loaded with Carmustine for Targeting Therapy of Glioma
Yunke Bi et al.
ACS APPLIED MATERIALS & INTERFACES (2016)
Increased Gold Nanoparticle Retention in Brain Tumors by in Situ Enzyme-Induced Aggregation
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ACS NANO (2016)
Increased Nanoparticle Delivery to Brain Tumors by Autocatalytic Priming for Improved Treatment and Imaging
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ACS NANO (2016)
The complexity of integrins in cancer and new scopes for therapeutic targeting
Hellyeh Hamidi et al.
BRITISH JOURNAL OF CANCER (2016)
Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype
Timothy N. Phoenix et al.
CANCER CELL (2016)
Characterization of passive permeability at the blood-tumor barrier in five preclinical models of brain metastases of breast cancer
Chris E. Adkins et al.
CLINICAL & EXPERIMENTAL METASTASIS (2016)
Alterations in Pericyte Subpopulations Are Associated with Elevated Blood-Tumor Barrier Permeability in Experimental Brain Metastasis of Breast Cancer
L. Tiffany Lyle et al.
CLINICAL CANCER RESEARCH (2016)
Impact of Blood-Brain Barrier Integrity on Tumor Growth and Therapy Response in Brain Metastases
Matthias Osswald et al.
CLINICAL CANCER RESEARCH (2016)
Evolving Drug Delivery Strategies to Overcome the Blood Brain Barrier
David S. Hersh et al.
CURRENT PHARMACEUTICAL DESIGN (2016)
Pathophysiological implications of neurovascular P450 in brain disorders
Chaitali Ghosh et al.
DRUG DISCOVERY TODAY (2016)
Preclinical comparison of the blood brain barrier (BBB) permeability of osimertinib (AZD9291) with other irreversible next generation EGFR TKIs
N. Colclough et al.
EUROPEAN JOURNAL OF CANCER (2016)
Matrix metalloproteinases in the brain and blood-brain barrier: Versatile breakers and makers
Ralf G. Rempe et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2016)
Distribution of polymer nanoparticles by convection-enhanced delivery to brain tumors
Jennifer K. Saucier-Sawyer et al.
JOURNAL OF CONTROLLED RELEASE (2016)
Small Molecule Kinase Inhibitors for the Treatment of Brain Cancer
Timothy P. Heffron
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Identification of residual tumor with intraoperative contrast-enhanced ultrasound during glioblastoma resection
Francesco Prada et al.
NEUROSURGICAL FOCUS (2016)
Glioblastoma Multiforme Recurrence: An Exploratory Study of 18F FPPRGD 2 PET/CT (vol 277, pg 497, 2015)
Andrei Iagaru et al.
RADIOLOGY (2016)
In vivo Target Residence Time and Kinetic Selectivity: The Association Rate Constant as Determinant
Wilhelmus E. A. de Witte et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2016)
Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment
Keisuke Katsushima et al.
NATURE COMMUNICATIONS (2016)
Brain tumor modeling using the CRISPR/Cas9 system: state of the art and view to the future
Xiao-Yuan Mao et al.
ONCOTARGET (2016)
Cilengitide in newly diagnosed glioblastoma: biomarker expression and outcome
Michael Weller et al.
ONCOTARGET (2016)
Safety Evaluation and Imaging Properties of Gadolinium-Based Nanoparticles in nonhuman primates
Shady Kotb et al.
SCIENTIFIC REPORTS (2016)
MRI Virtual Biopsy and Treatment of Brain Metastatic Tumors with Targeted Nanobioconjugates: Nanoclinic in the Brain
Rameshwar Patil et al.
ACS NANO (2015)
Long-Term in Vivo Clearance of Gadolinium-Based AGuIX Nanoparticles and Their Biocompatibility after Systemic Injection
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ACS NANO (2015)
Toward a full understanding of the EPR effect in primary and metastatic tumors as well as issues related to its heterogeneity
Hiroshi Maeda
ADVANCED DRUG DELIVERY REVIEWS (2015)
The Use of Anthracyclines for Therapy of CNS Tumors
Martina Ros et al.
Anti-Cancer Agents in Medicinal Chemistry (2015)
Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy
Suzanne L. Topalian et al.
CANCER CELL (2015)
Preclinical Mouse Cancer Models: A Maze of Opportunities and Challenges
Chi-Ping Day et al.
CELL (2015)
Biocompatible nanoparticles sensing the matrix metallo-proteinase 2 for the on-demand release of anticancer drugs in 3D tumor spheroids
Marco Cantisani et al.
COLLOIDS AND SURFACES B-BIOINTERFACES (2015)
Transferrin receptors and glioblastoma multiforme: Current findings and potential for treatment
Brittany Voth et al.
JOURNAL OF CLINICAL NEUROSCIENCE (2015)
Enhancing Glioblastoma-Specific Penetration by Functionalization of Nanoparticles with an Iron-Mimic Peptide Targeting Transferrin/Transferrin Receptor Complex
Ting Kang et al.
MOLECULAR PHARMACEUTICS (2015)
A tumor-targeting p53 nanodelivery system limits chemoresistance to temozolomide prolonging survival in a mouse model of glioblastoma multiforme
Sang-Soo Kim et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2015)
Increased brain uptake of targeted nanoparticles by adding an acid-cleavable linkage between transferrin and the nanoparticle core
Andrew J. Clark et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Glioblastoma Multiforme Recurrence: An Exploratory Study of 18F FPPRGD2 PET/CT1
Andrei Iagaru et al.
RADIOLOGY (2015)
Understanding Heterogeneity and Permeability of Brain Metastases in Murine Models of HER2-Positive Breast Cancer Through Magnetic Resonance Imaging: Implications for Detection and Therapy
Donna H. Murrell et al.
TRANSLATIONAL ONCOLOGY (2015)
Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets
Priscilla K. Brastianos et al.
CANCER DISCOVERY (2015)
Vascular heterogeneity and targeting: the role of YKL-40 in glioblastoma vascularization
Rong Shao et al.
ONCOTARGET (2015)
Periostin: a potent chemotactic factor for recruiting tumor-associated macrophage
Tiantian Wu et al.
PROTEIN & CELL (2015)
Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma
Anna Sophie Berghoff et al.
NEURO-ONCOLOGY (2015)
Efflux Transporters at the Blood-Brain Barrier Limit Delivery and Efficacy of Cyclin-Dependent Kinase 4/6 Inhibitor Palbociclib (PD-0332991) in an Orthotopic Brain Tumor Model
Karen E. Parrish et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2015)
Delivery of local therapeutics to the brain: working toward advancing treatment for malignant gliomas
Kaisorn L. Chaichana et al.
THERAPEUTIC DELIVERY (2015)
Light-Induced Cytosolic Activation of Reduction-Sensitive Camptothecin-Loaded Polymeric Micelles for Spatiotemporally Controlled in Vivo Chemotherapy
Hung-Chi Yen et al.
ACS NANO (2014)
Brain-Penetrating Nanoparticles Improve Paclitaxel Efficacy in Malignant Glioma Following Local Administration
Elizabeth Nance et al.
ACS NANO (2014)
Why Primate Models Matter
Kimberley A. Phillips et al.
AMERICAN JOURNAL OF PRIMATOLOGY (2014)
Phase I dose escalating study of 2B3-101, glutathione PEGylated liposomal doxorubicin, in patients with solid tumors and brain metastases or recurrent malignant glioma
Pieter J. Gaillard et al.
CANCER RESEARCH (2014)
Molecular mechanisms of ATP secretion during immunogenic cell death
I. Martins et al.
CELL DEATH AND DIFFERENTIATION (2014)
In vivo models of brain tumors: roles of genetically engineered mouse models in understanding tumor biology and use in preclinical studies
Iva Simeonova et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2014)
In vivo and ex vivo assessment of the blood brain barrier integrity in different glioblastoma animal models
Cindy Leten et al.
JOURNAL OF NEURO-ONCOLOGY (2014)
Enhanced Doxorubicin Delivery to the Brain Administered Through Glutathione PEGylated Liposomal Doxorubicin (2B3-101) as Compared with Generic Caelyx,®/Doxil®A Cerebral Open Flow Microperfusion Pilot Study
Thomas Birngruber et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2014)
68Ga-PRGD2 PET/CT in the Evaluation of Glioma: A Prospective Study
Deling Li et al.
MOLECULAR PHARMACEUTICS (2014)
A PHASE I STUDY OF CONVECTION-ENHANCED DELIVERY OF LIPOSOMAL-IRINOTECAN USING REAL-TIME IMAGING WITH GADOLINIUM IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMA
Nicholas Butowski et al.
NEURO-ONCOLOGY (2014)
GBM's multifaceted landscape: highlighting regional and microenvironmental heterogeneity
Alenoush Vartanian et al.
NEURO-ONCOLOGY (2014)
Bevacizumab for glioblastoma: current indications, surgical implications, and future directions
Brandyn A. Castro et al.
NEUROSURGICAL FOCUS (2014)
Fibronectin expression in glioblastomas promotes cell cohesion, collective invasion of basement membrane in vitro and orthotopic tumor growth in mice
E. Serres et al.
ONCOGENE (2014)
Patient-Specific Metrics of Invasiveness Reveal Significant Prognostic Benefit of Resection in a Predictable Subset of Gliomas
Anne L. Baldock et al.
PLOS ONE (2014)
Gliomas and the vascular fragility of the blood brain barrier
Luiz Gustavo Dubois et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
Disruption of astrocyte-vascular coupling and the blood-brain barrier by invading glioma cells
Stacey Watkins et al.
NATURE COMMUNICATIONS (2014)
Brain tumor-targeted drug delivery strategies
Xiaoli Wei et al.
ACTA PHARMACEUTICA SINICA B (2014)
Reactive Oxygen Species Responsive Nanoprodrug to Treat Intracranial Glioblastoma
Bong-Seop Lee et al.
ACS NANO (2013)
Cyclic RGD-Linked Polymeric Micelles for Targeted Delivery of Platinum Anticancer Drugs to Glioblastoma through the Blood-Brain Tumor Barrier
Yutaka Miura et al.
ACS NANO (2013)
In Silico Prediction of Brain Exposure: Drug Free Fraction, Unbound Brain to Plasma Concentration Ratio and Equilibrium Half-Life
Morena Spreafico et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2013)
Characterization of the blood-brain barrier of metastatic and primary malignant neoplasms Laboratory investigation
Edjah K. Nduom et al.
JOURNAL OF NEUROSURGERY (2013)
Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface
Anna Salvati et al.
NATURE NANOTECHNOLOGY (2013)
Expression of Indoleamine 2,3-Dioxygenase and Correlation With Pathological Malignancy in Gliomas
Kentaro Mitsuka et al.
NEUROSURGERY (2013)
Transcytosis and brain uptake of transferrin-containing nanoparticles by tuning avidity to transferrin receptor
Devin T. Wiley et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Highly penetrative, drug-loaded nanocarriers improve treatment of glioblastoma
Jiangbing Zhou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Tumor-Associated Macrophages in Glioma: Friend or Foe?
Benjamin C. Kennedy et al.
JOURNAL OF ONCOLOGY (2013)
The mastermind approach to CNS drug therapy: translational prediction of human brain distribution, target site kinetics, and therapeutic effects
Elizabeth C. M. de Lange
FLUIDS AND BARRIERS OF THE CNS (2013)
Dual Environment-Responsive Polyplex Carriers for Enhanced Intracellular Delivery of Plasmid DNA
Mai Sanjoh et al.
BIOMACROMOLECULES (2012)
Predictive value of peripheral blood lymphocyte count in breast cancer patients treated with primary chemotherapy
Maria Angeles Vicente Conesa et al.
BREAST (2012)
The Blood-Brain Barrier: Its Influence in the Treatment of Brain Tumors Metastases
D. Fortin
CURRENT CANCER DRUG TARGETS (2012)
F-Actin Is an Evolutionarily Conserved Damage-Associated Molecular Pattern Recognized by DNGR-1, a Receptor for Dead Cells
Susan Ahrens et al.
IMMUNITY (2012)
Drug transport across the blood-brain barrier
William M. Pardridge
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2012)
Tumor-Infiltrating Monocytic Myeloid-Derived Suppressor Cells Mediate CCR5-Dependent Recruitment of Regulatory T Cells Favoring Tumor Growth
Eva Schlecker et al.
JOURNAL OF IMMUNOLOGY (2012)
Aquaporin 4: a player in cerebral edema and neuroinflammation
Andrew M. Fukuda et al.
JOURNAL OF NEUROINFLAMMATION (2012)
In vivo models of primary brain tumors: pitfalls and perspectives
Peter C. Huszthy et al.
NEURO-ONCOLOGY (2012)
Soluble factors secreted by glioblastoma cell lines facilitate recruitment, survival, and expansion of regulatory T cells: implications for immunotherapy
Courtney A. Crane et al.
NEURO-ONCOLOGY (2012)
Aquaporin-4 upregulated expression in glioma tissue is a reaction to glioma-associated edema induced by vascular endothelial growth factor
Lijuan Yang et al.
ONCOLOGY REPORTS (2012)
Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase
Luc Pilotte et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Brain Tumors
Karl Herholz et al.
SEMINARS IN NUCLEAR MEDICINE (2012)
Macrophage migration inhibitory factor (MIF) expression in human malignant gliomas contributes to immune escape and tumour progression
Michel Mittelbronn et al.
ACTA NEUROPATHOLOGICA (2011)
Current review of in vivo GBM rodent models: emphasis on the CNS-1 tumour model
Valerie L. Jacobs et al.
ASN NEURO (2011)
Dual targeting effect of Angiopep-2-modified, DNA-loaded nanoparticles for glioma
Shixian Huang et al.
BIOMATERIALS (2011)
Experimental immunotherapy for malignant glioma: lessons from two decades of research in the GL261 model
Wim Maes et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2011)
Acidic stress promotes a glioma stem cell phenotype
A. B. Hjelmeland et al.
CELL DEATH AND DIFFERENTIATION (2011)
Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF-β
Jennifer Lohr et al.
CLINICAL CANCER RESEARCH (2011)
Blood-Brain Barrier P450 Enzymes and Multidrug Transporters in Drug Resistance: A Synergistic Role in Neurological Diseases
Chaitali Ghosh et al.
CURRENT DRUG METABOLISM (2011)
Phase 2 trial of temozolomide and pegylated liposomal doxorubicin in the treatment of patients with glioblastoma multiforme following concurrent radiotherapy and chemotherapy
Sumitra Ananda et al.
JOURNAL OF CLINICAL NEUROSCIENCE (2011)
Adenosine Receptor Signaling Modulates Permeability of the Blood-Brain Barrier
Aaron J. Carman et al.
JOURNAL OF NEUROSCIENCE (2011)
Metabolism of the EGFR tyrosin kinase inhibitor gefitinib by cytochrome P450 1A1 enzyme in EGFR-wild type non small cell lung cancer cell lines
Roberta R. Alfieri et al.
MOLECULAR CANCER (2011)
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size
H. Cabral et al.
NATURE NANOTECHNOLOGY (2011)
Interfering with pH regulation in tumours as a therapeutic strategy
Dario Neri et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma
Baisakhi Raychaudhuri et al.
NEURO-ONCOLOGY (2011)
Improving Drug Potency and Efficacy by Nanocarrier-Mediated Subcellular Targeting
Mami Murakami et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Integrin Targeted Therapeutics
Melissa Millard et al.
THERANOSTICS (2011)
Heterogeneous Blood-Tumor Barrier Permeability Determines Drug Efficacy in Experimental Brain Metastases of Breast Cancer
Paul R. Lockman et al.
CLINICAL CANCER RESEARCH (2010)
Mechanism of tumor cell-induced T-cell apoptosis mediated by galectin-1
Ferenc Kovacs-Solyom et al.
IMMUNOLOGY LETTERS (2010)
Scale to Predict Survival After Surgery for Recurrent Glioblastoma Multiforme
John K. Park et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
AQP-4 in peritumoral edematous tissue is correlated with the degree of glioma and with expression of VEGF and HIF-alpha
Kejie Mou et al.
JOURNAL OF NEURO-ONCOLOGY (2010)
Prognostic significance and mechanism of Treg infiltration in human brain tumors
Joannes F. M. Jacobs et al.
JOURNAL OF NEUROIMMUNOLOGY (2010)
Canine spontaneous glioma: A translational model system for convection-enhanced delivery
Peter J. Dickinson et al.
NEURO-ONCOLOGY (2010)
RNOP-09: Pegylated liposomal doxorubicine and prolonged temozolomide in addition to radiotherapy in newly diagnosed glioblastoma - a phase II study
Christoph P. Beier et al.
BMC CANCER (2009)
Resonant X-ray Enhancement of the Auger Effect in High-Z Atoms, Molecules, and Nanoparticles: Potential Biomedical Applications
Anil K. Pradhan et al.
JOURNAL OF PHYSICAL CHEMISTRY A (2009)
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
Michael R. Elliott et al.
NATURE (2009)
Imaging of integrin αvβ3 expression in patients with malignant glioma by [18F] Galacto-RGD positron emission tomography
Oliver Schnell et al.
NEURO-ONCOLOGY (2009)
Molecular Epigenetics and Genetics in Neuro-Oncology
Raman P. Nagarajan et al.
NEUROTHERAPEUTICS (2009)
Are animal models predictive for humans?
Niall Shanks et al.
Philosophy Ethics and Humanities in Medicine (2009)
Expression of integrin αvβ3 in gliomas correlates with tumor grade and is not restricted to tumor vasculature
Oliver Schnell et al.
BRAIN PATHOLOGY (2008)
Aggressive Infantile Embryonal Tumors
Tobey J. MacDonald
JOURNAL OF CHILD NEUROLOGY (2008)
Randomized Phase II Study of Cilengitide, an Integrin-Targeting Arginine-Glycine-Aspartic Acid Peptide, in Recurrent Glioblastoma Multiforme
David A. Reardon et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
Role of galectin-1 in migration and invasion of human glioblastoma multiforme cell lines
Tae-Young Jung et al.
JOURNAL OF NEUROSURGERY (2008)
Delivery of galanin-like peptide to the brain: Targeting with intranasal delivery and cyclodextrins
Naoko Nonaka et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
Identification and design of peptides as a new drug delivery system for the brain
Michel Demeule et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
Intracranial glioblastoma models in preclinical neuro-oncology: neuropathological characterization and tumor progression
Marianela Candolfi et al.
JOURNAL OF NEURO-ONCOLOGY (2007)
In vitro methods for estimating unbound drug concentrations in the brain interstitial and intracellular fluids
Markus Friden et al.
DRUG METABOLISM AND DISPOSITION (2007)
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
Lionel Apetoh et al.
NATURE MEDICINE (2007)
Human brain tumors:: multidrug-resistance P-glycoprotein expression in tumor cells and intratumoral capillary endothelial cells
Silvia Fattori et al.
VIRCHOWS ARCHIV (2007)
Increased permeability of the blood-brain barrier to chemotherapy in metastatic brain tumors: Establishing a treatment paradigm
Elizabeth R. Gerstner et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Genetic pathways to primary and secondary glioblastoma
Hiroko Ohgaki et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
The in vivo antitumoral effects of lipopolysaccharide against glioblastoma multiforme are mediated in part by toll-like receptor 4
Michael R. Chicoine et al.
NEUROSURGERY (2007)
The integrins
Yoshikazu Takada et al.
GENOME BIOLOGY (2007)
Calreticulin exposure dictates the immunogenicity of cancer cell death
Michel Obeid et al.
NATURE MEDICINE (2007)
Transposon-based interferon gamma gene transfer overcomes limitations of episomal plasmid for immunogene therapy of glioblastoma
A. Wu et al.
CANCER GENE THERAPY (2007)
Gefitinib accumulation in glioblastoma tissue
Silvia Hofer et al.
CANCER BIOLOGY & THERAPY (2006)
In vivo diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space
RG Thorne et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death
BN Stillman et al.
JOURNAL OF IMMUNOLOGY (2006)
Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+ CD25+ regulatory T cells
H Zhang et al.
NATURE MEDICINE (2005)
HLA-E protects glioma cells from NKG2D-mediated immune responses in vitro: Implications for immune escape in vivo
J Wischhusen et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2005)
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
R Stupp et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Glioblastoma multiforme in three baboons (Papio spp.)
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