4.7 Review

Laser ablation: Heating up the anti-tumor response in the intracranial compartment

Related references

Note: Only part of the references are listed.
Article Clinical Neurology

Time to Steroid Independence After Laser Interstitial Thermal Therapy vs Medical Management for Treatment of Biopsy-Proven Radiation Necrosis Secondary to Stereotactic Radiosurgery for Brain Metastasis

Eric W. Sankey et al.

Summary: This study compared LITT with medical management for the treatment of radiation necrosis. The findings showed that patients treated with LITT were able to stop using steroids earlier and there was no significant difference in overall survival or freedom from local progression. These results suggest the potential benefits of LITT for the treatment of radiation necrosis.

NEUROSURGERY (2022)

Review Oncology

A review of glioblastoma immunotherapy

Ravi Medikonda et al.

Summary: Current immunotherapy treatments for glioblastoma, including checkpoint inhibitors and vaccine therapy, have shown disappointing results in clinical trials due to the highly immunosuppressive environment and therapy resistance mechanisms of the tumor. Ongoing research is focusing on exploring combination therapies and novel treatment strategies beyond immune checkpoint therapies, as well as establishing synergy between immunotherapy and current standard of care to improve treatment outcomes. Recent advances in personalized neoantigen vaccines suggest a shift towards personalized, patient-specific treatment for glioblastoma.

JOURNAL OF NEURO-ONCOLOGY (2021)

Article Oncology

Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma

J. Bryan Iorgulescu et al.

Summary: The study indicates that concurrent dexamethasone therapy may have detrimental effects on immunotherapeutic approaches in patients with glioblastoma, by reducing T-lymphocyte numbers and functionality, as well as decreasing myeloid and natural killer cell populations.

CLINICAL CANCER RESEARCH (2021)

Article Multidisciplinary Sciences

Immune modulation resulting from MR-guided high intensity focused ultrasound in a model of murine breast cancer

Brett Z. Fite et al.

Summary: High intensity focused ultrasound (HIFU) can rapidly and non-invasively destroy tumor tissue. A combination of HIFU with innate immune agonist CpG and checkpoint inhibitor anti-PD-1 can modulate the immune response, leading to enhanced anti-tumor effects. Both mechanical disruption HIFU and thermal ablation induce potent inflammatory responses, while priming with CpG can further enhance immune response, alter macrophage polarization, and increase T-cell activation.

SCIENTIFIC REPORTS (2021)

Article Biotechnology & Applied Microbiology

Dual activity of PD-L1 targeted Doxorubicin immunoliposomes promoted an enhanced efficacy of the antitumor immune response in melanoma murine model

Maria Merino et al.

Summary: The study successfully evaluated the combination of chemotherapy and ICI by developing Dox Immunoliposomes functionalized with monovalent-variable fragments (Fab') of alpha-PD-L1, showing promising results in a B16 OVA melanoma murine cell line.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

Article Nanoscience & Nanotechnology

Mild magnetic nanoparticle hyperthermia promotes the disaggregation and microglia-mediated clearance of beta-amyloid plaques

Eric Dyne et al.

Summary: The study validated the use of mild magnetic nanoparticle hyperthermia technology as a new strategy for clearing Aβ plaques in AD patients, demonstrating its potential to facilitate phagocytic clearance of Aβ by human microglial cells and attenuate inflammatory responses.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2021)

Article Oncology

Laser interstitial thermal therapy for brain metastases

Ethan S. Srinivasan et al.

Summary: Laser interstitial thermal therapy (LITT) is a minimally invasive treatment for intracranial lesions, showing promising results in the treatment of metastatic disease and radiographically progressive lesions after stereotactic radiosurgery. It is particularly advantageous for high-risk surgical candidates or patients with lesions in difficult to access locations. Further exploration of its use in metastatic disease will provide insights into its indications, benefits, and future directions.

NEURO-ONCOLOGY ADVANCES (2021)

Review Biochemistry & Molecular Biology

Challenges to Successful Implementation of the Immune Checkpoint Inhibitors for Treatment of Glioblastoma

Stephanie Sanders et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Oncology

The effect of thermal therapy on the blood-brain barrier and blood-tumor barrier

Bhuvic Patel et al.

INTERNATIONAL JOURNAL OF HYPERTHERMIA (2020)

Article Multidisciplinary Sciences

A decade of immune-checkpoint inhibitors in cancer therapy

Caroline Robert

NATURE COMMUNICATIONS (2020)

Review Clinical Neurology

Management of brain metastases according to molecular subtypes

Riccardo Soffietti et al.

NATURE REVIEWS NEUROLOGY (2020)

Review Pharmacology & Pharmacy

Blood-Brain Barrier Modulation to Improve Glioma Drug Delivery

Huilong Luo et al.

PHARMACEUTICS (2020)

Review Oncology

Brain immunology and immunotherapy in brain tumours

John H. Sampson et al.

NATURE REVIEWS CANCER (2020)

Review Oncology

Immunotherapy in CNS cancers: the role of immune cell trafficking

Nivedita M. Ratnam et al.

NEURO-ONCOLOGY (2019)

Article Multidisciplinary Sciences

Blood-brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy

Anna Galstyan et al.

NATURE COMMUNICATIONS (2019)

Article Multidisciplinary Sciences

Dual microglia effects on blood brain barrier permeability induced by systemic inflammation

Koichiro Haruwaka et al.

NATURE COMMUNICATIONS (2019)

Article Cell Biology

Neuroinflammatory mechanisms of blood-brain barrier damage in ischemic stroke

Changjun Yang et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2019)

Article Biotechnology & Applied Microbiology

Role of synergy and immunostimulation in design of chemotherapy combinations: An analysis of doxorubicin and camptothecin

Anusha Pusuluri et al.

BIOENGINEERING & TRANSLATIONAL MEDICINE (2019)

Review Oncology

T-cell Dysfunction in Glioblastoma: Applying a New Framework

Karolina I. Woroniecka et al.

CLINICAL CANCER RESEARCH (2018)

Article Oncology

T-Cell Exhaustion Signatures Vary with Tumor Type and Are Severe in Glioblastoma

Karolina Woroniecka et al.

CLINICAL CANCER RESEARCH (2018)

Article Clinical Neurology

Magnetic resonance-guided interstitial high-intensity focused ultrasound for brain tumor ablation

Jacquelyn MacDonell et al.

NEUROSURGICAL FOCUS (2018)

Review Clinical Neurology

Laser-Induced Thermal Therapy in Neuro-Oncology: A Review

Omar Ashraf et al.

WORLD NEUROSURGERY (2018)

Article Biochemistry & Molecular Biology

Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors

Pakawat Chongsathidkiet et al.

NATURE MEDICINE (2018)

Article Medicine, General & Internal

Combined Nivolumab and Ipilimumab in Melanoma Metastatic to the Brain

Hussein A. Tawbi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Review Neurosciences

CNS infection and immune privilege

John V. Forrester et al.

NATURE REVIEWS NEUROSCIENCE (2018)

Article Oncology

Radiation effects on antitumor immune responses: current perspectives and challenges

Thomas Walle et al.

THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2018)

Article Chemistry, Multidisciplinary

MR image-guided delivery of cisplatin-loaded brain-penetrating nanoparticles to invasive glioma with focused ultrasound

Kelsie F. Timbie et al.

JOURNAL OF CONTROLLED RELEASE (2017)

Review Radiology, Nuclear Medicine & Medical Imaging

Thermal ablation and immunomodulation: From preclinical experiments to clinical trials

H. Takaki et al.

DIAGNOSTIC AND INTERVENTIONAL IMAGING (2017)

Review Pharmacology & Pharmacy

Doxorubicin: nanotechnological overviews from bench to bedside

Maximiliano Cagel et al.

DRUG DISCOVERY TODAY (2017)

Review Immunology

The blood-brain barrier in systemic inflammation

Aravinthan Varatharaj et al.

BRAIN BEHAVIOR AND IMMUNITY (2017)

Review Immunology

The movers and shapers in immune privilege of the CNS

Britta Engelhardt et al.

NATURE IMMUNOLOGY (2017)

Article Pharmacology & Pharmacy

Evolving Drug Delivery Strategies to Overcome the Blood Brain Barrier

David S. Hersh et al.

CURRENT PHARMACEUTICAL DESIGN (2016)

Article Oncology

Characterizing the peritumoral brain zone in glioblastoma: a multidisciplinary analysis

Jean-Michel Lemee et al.

JOURNAL OF NEURO-ONCOLOGY (2015)

Article Multidisciplinary Sciences

Structural and functional features of central nervous system lymphatic vessels

Antoine Louveau et al.

NATURE (2015)

Article Clinical Neurology

Renaissance of laser interstitial thermal ablation

Symeon Missios et al.

NEUROSURGICAL FOCUS (2015)

Review Multidisciplinary Sciences

Neoantigens in cancer immunotherapy

Ton N. Schumacher et al.

SCIENCE (2015)

Review Biochemistry & Molecular Biology

Immunogenicity of necrotic cell death

Jaba Gamrekelashvili et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2015)

Article Clinical Neurology

Cerebrospinal fluid aquaporin-4-immunoglobulin G disrupts blood brain barrier

Nasrin Asgari et al.

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2015)

Article Oncology

Immunotherapy for Primary Brain Tumors: No Longer a Matter of Privilege

Peter E. Fecci et al.

CLINICAL CANCER RESEARCH (2014)

Article Nanoscience & Nanotechnology

Local hyperthermia treatment of tumors induces CD8+ T cell-mediated resistance against distal and secondary tumors

Seiko Toraya-Brown et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2014)

Article Multidisciplinary Sciences

Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

Matthew M. Gubin et al.

NATURE (2014)

Review Oncology

Thermal ablation of tumours: biological mechanisms and advances in therapy

Katrina F. Chu et al.

NATURE REVIEWS CANCER (2014)

Review Oncology

Challenges With the Diagnosis and Treatment of Cerebral Radiation Necrosis

Samuel T. Chao et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2013)

Review Clinical Neurology

Cerebral radiation necrosis: A review of the pathobiology, diagnosis and management considerations

Gazanfar Rahmathulla et al.

JOURNAL OF CLINICAL NEUROSCIENCE (2013)

Article Radiology, Nuclear Medicine & Medical Imaging

Image-guided Thermal Ablation of Tumors Increases the Plasma Level of Interleukin-6 and Interleukin-10

Joseph P. Erinjeri et al.

JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY (2013)

Article Biochemistry & Molecular Biology

Ultrasound-Induced Blood-Brain Barrier Opening

Elisa E. Konofagou et al.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2012)

Article Oncology

Effector CD8(+) T cell IFN-gamma production and cytotoxicity are enhanced by mild hyperthermia

Thomas A. Mace et al.

INTERNATIONAL JOURNAL OF HYPERTHERMIA (2012)

Review Clinical Neurology

Cancer Immunoediting in Malignant Glioma

Gavin P. Dunn et al.

NEUROSURGERY (2012)

Article Medicine, General & Internal

Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma

Michael A. Postow et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Review Pharmacology & Pharmacy

Cytokine Signaling Modulates Blood-Brain Barrier Function

Weihong Pan et al.

CURRENT PHARMACEUTICAL DESIGN (2011)

Review Multidisciplinary Sciences

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

Robert D. Schreiber et al.

SCIENCE (2011)

Article Cell Biology

Desirable cell death during anticancer chemotherapy

Clara Locher et al.

CLEARANCE OF DYING CELLS IN HEALTHY AND DISEASED IMMUNE SYSTEMS (2010)

Article Endocrinology & Metabolism

Reorganization of gap junctions after focused ultrasound blood-brain barrier opening in the rat brain

Angelika Alonso et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2010)

Article Neurosciences

PERMEABILITY OF THE BLOOD-BRAIN BARRIER DEPENDS ON BRAIN TEMPERATURE

E. A. Kiyatkin et al.

NEUROSCIENCE (2009)

Article Oncology

Dissecting the role of hyperthermia in natural killer cell mediated anti-tumor responses

Baris E. Dayanc et al.

INTERNATIONAL JOURNAL OF HYPERTHERMIA (2008)

Article Oncology

Cellular responses to hyperthermia (40-46 degrees C): Cell killing and molecular events

Joseph L. Roti Roti

INTERNATIONAL JOURNAL OF HYPERTHERMIA (2008)

Review Radiology, Nuclear Medicine & Medical Imaging

MR thermometry

Viola Rieke et al.

JOURNAL OF MAGNETIC RESONANCE IMAGING (2008)

Article Pharmacology & Pharmacy

Cyclooxygenase inhibition limits blood-brain barrier disruption following intracerebral injection of tumor necrosis factor-α in the rat

Eduardo Candelario-Jalil et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)

Review Immunology

Structure and function: Heat shock proteins and adaptive immunity

Babak Javid et al.

JOURNAL OF IMMUNOLOGY (2007)

Article Oncology

Dynamic control of lymphocyte trafficking by fever-range thermal stress

Q Chen et al.

CANCER IMMUNOLOGY IMMUNOTHERAPY (2006)

Article Gastroenterology & Hepatology

Activation of dendritic cells by local ablation of hepatocellular carcinoma

MY Ali et al.

JOURNAL OF HEPATOLOGY (2005)

Article Oncology

High-intensity focused ultrasound in the treatment of solid tumours

JE Kennedy

NATURE REVIEWS CANCER (2005)

Article Multidisciplinary Sciences

Requirement for caspase-8 in NF-κB activation by antigen receptor

H Su et al.

SCIENCE (2005)

Article Immunology

Hyperthermia enhances CD95-ligand gene expression in T lymphocytes

M Cippitelli et al.

JOURNAL OF IMMUNOLOGY (2005)

Article Multidisciplinary Sciences

Essential role of CD91 in re-presentation of gp96-chaperoned peptides

RJ Binder et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Review Cell Biology

The heat-shock protein receptors: some answers and more questions

RJ Binder et al.

TISSUE ANTIGENS (2004)

Article Oncology

Thermal regulation of dendritic cell activation and migration from skin explants

JR Ostberg et al.

INTERNATIONAL JOURNAL OF HYPERTHERMIA (2003)

Article Cell Biology

Fever-like thermal conditions regulate the activation of maturing dendritic cells

JN Tournier et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2003)

Review Immunology

Cancer immunoediting: from immunosurveillance to tumor escape

GP Dunn et al.

NATURE IMMUNOLOGY (2002)

Article Immunology

Heat shock fusion protein gp96-Ig mediates strong CD8 CTL expansion in vivo

N Strbo et al.

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2002)

Article Biochemistry & Molecular Biology

Novel signal transduction pathway utilized by extracellular HSP70 -: Role of Toll-like receptor (TLR) 2 AND TLR4

A Asea et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Immunology

Heat shock proteins gp96 and hsp70 activate the release of nitric oxide by APCs

NN Panjwani et al.

JOURNAL OF IMMUNOLOGY (2002)

Article Acoustics

High-intensity focused ultrasound selectively disrupts the blood-brain barrier in vivo

AH Mesiwala et al.

ULTRASOUND IN MEDICINE AND BIOLOGY (2002)

Article Radiology, Nuclear Medicine & Medical Imaging

Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbits

K Hynynen et al.

RADIOLOGY (2001)

Article Biochemistry & Molecular Biology

Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming

J Wolfers et al.

NATURE MEDICINE (2001)

Article Cell Biology

Inflammatory mediators and modulation of blood-brain barrier permeability

NJ Abbott

CELLULAR AND MOLECULAR NEUROBIOLOGY (2000)

Article Biophysics

Supraphysiological thermal injury in Dunning AT-1 prostate tumor cells

S Bhowmick et al.

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME (2000)