4.1 Article

Impact of delivery rate on the acute response to intravenous nicotine: A human laboratory study with implications for regulatory science

Related references

Note: Only part of the references are listed.
Article Psychology, Biological

The Effects of Inhaled Flavors on Intravenous Nicotine

R. Ross MacLean et al.

Summary: This study examined whether flavors inhaled through an e-cigarette would enhance the acute rewarding effects of nicotine administered intravenously. Across multiple domains, there was an expected dose dependent response to nicotine; however, flavor had minimal to no effect on the acute effects of nicotine. Any potential enhancement of nicotine via e-cigarette flavors is likely complex and may depend on a variety of characteristics including flavor preference and e-cigarette experience.

EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY (2021)

Article Medicine, Research & Experimental

Mechanisms of Nicotine Addiction

Marina R. Picciotto et al.

Summary: Tobacco smoking, with nicotine as the major reinforcing component, acts on the brain through nAChRs, mediating addictive behaviors. Genetic variations in nAChR subunits are associated with vulnerability to tobacco dependence, affecting patterns of nicotine consumption in mice. In addition to reinforcing properties, nicotine's effects on appetite, attention, and mood also contribute to tobacco smoking dependence.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2021)

Article Psychology, Clinical

Acute effects of inhaled menthol on cognitive effects of intravenous nicotine among young adult cigarette smokers

Nancy C. Jao et al.

Summary: The study on the cognitive effects of menthol and nicotine among cigarette smokers showed that there were no significant differences between menthol and nonmenthol smokers in cognitive task performance, but high nicotine dose significantly improved accuracy in the Stroop task, and low menthol showed better performance in the Stroop task. Further research on the impact of different levels of menthol and nicotine in nicotine products may provide more insights into the role of menthol in smoking behavior.

ADDICTIVE BEHAVIORS (2021)

Article Medicine, General & Internal

Automated Neuropsychological Assessment Metrics (v4) Military Battery: Military Normative Data

John E. Meyers et al.

MILITARY MEDICINE (2020)

Review Substance Abuse

Biochemical Verification of Tobacco Use and Abstinence: 2019 Update

Neal L. Benowitz et al.

NICOTINE & TOBACCO RESEARCH (2020)

Review Medicine, General & Internal

In times of tobacco-free nicotine consumption: The influence of nicotine on vascular calcification

Milen Babic et al.

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2019)

Review Psychology, Multidisciplinary

Cholinergic double duty: cue detection and attentional control

Martin Sarter et al.

CURRENT OPINION IN PSYCHOLOGY (2019)

Review Neurosciences

E-cigarettes: Impact of E-liquid Components and Device Characteristics on Nicotine Exposure

Elise E. DeVito et al.

CURRENT NEUROPHARMACOLOGY (2018)

Review Neurosciences

Cognitive Effects of Nicotine: Recent Progress

Gerald Valentine et al.

CURRENT NEUROPHARMACOLOGY (2018)

Article Neurosciences

A CHRNA5 Smoking Risk Variant Decreases the Aversive Effects of Nicotine in Humans

Kevin P. Jensen et al.

NEUROPSYCHOPHARMACOLOGY (2015)

Review Behavioral Sciences

How fast and how often: The pharmacokinetics of drug use are decisive in addiction

Florence Allain et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2015)

Editorial Material Substance Abuse

Electronic Cigarette Effectiveness and Abuse Liability: Predicting and Regulating Nicotine Flux

Alan Shihadeh et al.

NICOTINE & TOBACCO RESEARCH (2015)

Article Genetics & Heredity

FKBP5 variation is associated with the acute and chronic effects of nicotine

K. P. Jensen et al.

PHARMACOGENOMICS JOURNAL (2015)

Article Multidisciplinary Sciences

Puffing Topography and Nicotine Intake of Electronic Cigarette Users

Rachel Z. Behar et al.

PLOS ONE (2015)

Article Multidisciplinary Sciences

Nicotine absorption from electronic cigarette use: comparison between first and new-generation devices

Konstantinos E. Farsalinos et al.

SCIENTIFIC REPORTS (2014)

Article Behavioral Sciences

Effect of infusion rate on intravenous nicotine self-administration in rats

Victoria C. Wing et al.

BEHAVIOURAL PHARMACOLOGY (2013)

Article Neurosciences

The Speed of Cocaine Delivery Determines the Subsequent Motivation to Self-Administer the Drug

Ellie-Anna Minogianis et al.

NEUROPSYCHOPHARMACOLOGY (2013)

Review Pharmacology & Pharmacy

Nicotinic acetylcholine receptors: From basic science to therapeutics

Raymond Hurst et al.

PHARMACOLOGY & THERAPEUTICS (2013)

Article Neurosciences

The drug effects questionnaire: psychometric support across three drug types

Meghan E. Morean et al.

PSYCHOPHARMACOLOGY (2013)

Review Neurosciences

Nicotine addiction and nicotinic receptors: lessons from genetically modified mice

Jean-Pierre Changeux

NATURE REVIEWS NEUROSCIENCE (2010)

Review Neurosciences

Meta-analysis of the acute effects of nicotine and smoking on human performance

Stephen J. Heishman et al.

PSYCHOPHARMACOLOGY (2010)

Article Pharmacology & Pharmacy

Rats Self-Administer Intravenous Nicotine Delivered in a Novel Smoking-Relevant Procedure: Effects of Dopamine Antagonists

Robert E. Sorge et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)

Article Neurosciences

Dose-related enhancement of mood and cognition in smokers administered nicotine nasal spray

Carol S. Myers et al.

NEUROPSYCHOPHARMACOLOGY (2008)

Review Substance Abuse

Effects of abstinence from tobacco: Valid symptoms and time course

John R. Hughes

NICOTINE & TOBACCO RESEARCH (2007)

Article Psychology, Biological

Transdermal nicotine-induced tobacco abstinence symptom suppression: Nicotine dose and smokers' gender

Sarah E. Evans et al.

EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY (2006)

Article Clinical Neurology

Influence of nicotine gum on acute cravings for cigarettes

GM Davies et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2004)

Review Behavioral Sciences

Assessing the abuse potential of methylphenidate in nonhuman and human subjects - A review

SH Kollins et al.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2001)

Article Oncology

Doses of nicotine and lung carcinogens delivered to cigarette smokers

MV Djordjevic et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2000)

Article Behavioral Sciences

Dissociating nicotine and nonnicotine components of cigarette smoking

JE Rose et al.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2000)