Antibiotic stewardship programmes had a low impact on prescribing for acute respiratory tract infections in children

Aim This mini review summarises the available data on antibiotic stewardship programmes (ASP) for acute respiratory tract infections (ARTI) in paediatric outpatients, particularly the implementation and impact of programmes. Methods PubMed was searched from 1 January 2012 to 31 December 2021 for papers with abstracts that used the terms respiratory tract infection, antibiotic, child and guideline. We then saw how many of these included the individual terms impact, implementation or stewardship. After exclusions, we included 10 papers that were published in English on children treated as outpatients for ARTIs. All of these included data on implementing and assessing the impact of ASPs. Results The primary care data were mainly from the United States. The ASP programmes did not influence antibiotic prescription rates, but broad-spectrum antibiotics decreased by 43-48%. The emergency department data were mainly from France and the antibiotic prescription rate decreased by 31-35% and the rate for broad-spectrum antibiotics by 63-71%. A nationwide register-based study from France confirmed these results. Conclusion ASPs had a low impact on overall antibiotic prescription rates and a modest impact on prescribing broad-spectrum antibiotics. The implementation of ASP protocols needs further development, and more research is necessary on barriers to complying with ASPs.

Automated summary

This mini review summarizes the available data on the implementation and impact of antibiotic stewardship programs (ASP) for acute respiratory tract infections (ARTI) in pediatric outpatients. The results suggest that ASPs have a low impact on overall antibiotic prescription rates and a modest impact on prescribing broad-spectrum antibiotics. However, the implementation of ASP protocols needs further development, and more research is necessary on barriers to complying with ASPs.