Related references
Note: Only part of the references are listed.Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy
Liwen Luo et al.
STEM CELLS (2021)
Hypoxic hUCMSC-derived extracellular vesicles attenuate allergic airway inflammation and airway remodeling in chronic asthma mice
Liyang Dong et al.
STEM CELL RESEARCH & THERAPY (2021)
INHIBITION OF TOLL-LIKE RECEPTOR 4 PROTECTS AGAINST INFLAMMATION-INDUCED MECHANOBIOLOGICAL ALTERATIONS TO INTERVERTEBRAL DISC CELLS
T. D. Jacobsen et al.
EUROPEAN CELLS & MATERIALS (2021)
Concise Review: Mesenchymal Stromal Cell-Derived Extracellular Vesicles for Regenerative Therapy and Immune Modulation: Progress and Challenges Toward Clinical Application
David S. Allan et al.
STEM CELLS TRANSLATIONAL MEDICINE (2020)
miR-381-abundant small extracellular vesicles derived from kartogenin-preconditioned mesenchymal stem cells promote chondrogenesis of MSCs by targeting TAOK1
Hui Jing et al.
BIOMATERIALS (2020)
Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway
Kang Wei et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2020)
Procyanidin B3 alleviates intervertebral disc degeneration via interaction with the TLR4/MD-2 complex
Ping Shang et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)
Exosome-shuttled miR-216a-5p from hypoxic preconditioned mesenchymal stem cells repair traumatic spinal cord injury by shifting microglial M1/M2 polarization
Wei Liu et al.
JOURNAL OF NEUROINFLAMMATION (2020)
Role of TLR2 and TLR4 in regulation of articular chondrocyte homeostasis
Y. Wang et al.
OSTEOARTHRITIS AND CARTILAGE (2020)
Lumican is upregulated in osteoarthritis and contributes to TLR4-induced pro-inflammatory activation of cartilage degradation and macrophage polarization
G. Barreto et al.
OSTEOARTHRITIS AND CARTILAGE (2020)
Resveratrol Exerts Anti-Osteoarthritic Effect by Inhibiting TLR4/NF-κB Signaling Pathway via the TLR4/Akt/FoxO1 Axis in IL-1β-Stimulated SW1353 Cells
Xiaolei Xu et al.
DRUG DESIGN DEVELOPMENT AND THERAPY (2020)
Mesenchymal stem cells-derived exosomes ameliorate nucleus pulposus cells apoptosis via delivering miR-142-3p: therapeutic potential for intervertebral disc degenerative diseases
Lifan Zhu et al.
CELL CYCLE (2020)
Kuijieyuan Decoction Improved Intestinal Barrier Injury of Ulcerative Colitis by Affecting TLR4-Dependent PI3K/AKT/NF-κB Oxidative and Inflammatory Signaling and Gut Microbiota
Baohai Liu et al.
FRONTIERS IN PHARMACOLOGY (2020)
circ_001653 Silencing Promotes the Proliferation and ECM Synthesis of NPCs in IDD by Downregulating miR-486-3p-Mediated CEMIP
Shaoqian Cui et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2020)
Mesenchymal stem cells-derived exosomes ameliorate intervertebral disc degeneration through inhibiting pyroptosis
Jingwei Zhang et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)
TLR4 promotes microglial pyroptosis via lncRNA-F630028O10Rik by activating PI3K/AKT pathway after spinal cord injury
Shun Xu et al.
CELL DEATH & DISEASE (2020)
Overexpression of LMP-1 Decreases Apoptosis in Human Nucleus Pulposus Cells via Suppressing the NF-κB Signaling Pathway
Yuan Liu et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2020)
Intervertebral disc regeneration: From cell therapy to the development of novel bioinspired endogenous repair strategies
Johann Clouet et al.
ADVANCED DRUG DELIVERY REVIEWS (2019)
Mesenchymal stromal cell-derived exosomes attenuatemyocardial ischaemia-reperfusion injury throughmiR-182-regulated macrophage polarization
Jinxuan Zhao et al.
CARDIOVASCULAR RESEARCH (2019)
Use of Allogeneic Hypoxic Mesenchymal Stem Cells For Treating Disc Degeneration in Rabbits
En-Rung Chiang et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2019)
Autogenic mesenchymal stem cells for intervertebral disc regeneration
Filippo Migliorini et al.
INTERNATIONAL ORTHOPAEDICS (2019)
Intervertebral disc regeneration with an adipose mesenchymal stem cell-derived tissue-engineered construct in a rat nucleotomy model
Hiroyuki Ishiguro et al.
ACTA BIOMATERIALIA (2019)
Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo
Zhiwei Liao et al.
THERANOSTICS (2019)
Mesenchymal stem cells deliver exogenous miR-21 via exosomes to inhibit nucleus pulposus cell apoptosis and reduce intervertebral disc degeneration
Xiaofei Cheng et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2018)
Low back pain and disc degeneration are decreased following chronic toll-like receptor 4 inhibition in a mouse model
Emerson Krock et al.
OSTEOARTHRITIS AND CARTILAGE (2018)
Preclinical development of a microRNA-based therapy for intervertebral disc degeneration
Ming-liang Ji et al.
NATURE COMMUNICATIONS (2018)
Mesenchymal Stromal Cell-Derived Extracellular Vesicles Attenuate Dendritic Cell Maturation and Function
Monica Reis et al.
FRONTIERS IN IMMUNOLOGY (2018)
Current knowledge on exosome biogenesis and release
Nina Pettersen Hessvik et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
Hypoxia-elicited mesenchymal stem cell-derived exosomes facilitates cardiac repair through miR-125b-mediated prevention of cell death in myocardial infarction
Ling-Ping Zhu et al.
THERANOSTICS (2018)
Mesenchymal Stem/Stromal Cell-Derived Extracellular Vesicles and Their Potential as Novel Immunomodulatory Therapeutic Agents
Verena Boerger et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016
Theo Vos et al.
LANCET (2017)
Safety and tolerability of intradiscal implantation of combined autologous adipose-derived mesenchymal stem cells and hyaluronic acid in patients with chronic discogenic low back pain: 1-year follow-up of a phase I study
Hemant Kumar et al.
STEM CELL RESEARCH & THERAPY (2017)
Exosomes as potential alternatives to stem cell therapy for intervertebral disc degeneration: in-vitro study on exosomes in interaction of nucleus pulposus cells and bone marrow mesenchymal stem cells
Kang Lu et al.
STEM CELL RESEARCH & THERAPY (2017)
Exosome-mediated inflammasome signaling after central nervous system injury
Juan Pablo de Rivero Vaccari et al.
JOURNAL OF NEUROCHEMISTRY (2016)
Mesenchymal stem cells in regenerative medicine: Focus on articular cartilage and intervertebral disc regeneration
Stephen M. Richardson et al.
METHODS (2016)
Exosomal miRNAs as cancer biomarkers and therapeutic targets
Arron Thind et al.
JOURNAL OF EXTRACELLULAR VESICLES (2016)
Exosome mediated communication within the tumor microenvironment
Lara Milane et al.
JOURNAL OF CONTROLLED RELEASE (2015)
Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013
Theo Vos et al.
LANCET (2015)
Mesenchymal Stem Cell-derived Extracellular Vesicles: Toward Cell-free Therapeutic Applications
Sweta Rani et al.
MOLECULAR THERAPY (2015)
Stem cell therapy for intervertebral disc regeneration: obstacles and solutions
Daisuke Sakai et al.
NATURE REVIEWS RHEUMATOLOGY (2015)
Mechanics and biology in intervertebral disc degeneration: a vicious circle
P. -P. A. Vergroesen et al.
OSTEOARTHRITIS AND CARTILAGE (2015)
Hypoxic Preconditioning of Mesenchymal Stromal Cells Induces Metabolic Changes, Enhances Survival, and Promotes Cell Retention In Vivo
Julie Beegle et al.
STEM CELLS (2015)
HucMSC-Exosome Mediated-Wnt4 Signaling Is Required for Cutaneous Wound Healing
Bin Zhang et al.
STEM CELLS (2015)
Exosome and Exosomal MicroRNA: Trafficking, Sorting, and Function
Jian Zhang et al.
GENOMICS PROTEOMICS & BIOINFORMATICS (2015)
Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper
Thomas Lener et al.
JOURNAL OF EXTRACELLULAR VESICLES (2015)
Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis
Sonia A. Melo et al.
CANCER CELL (2014)
Effects of hypoxia on differentiation from human placenta-derived mesenchymal stem cells to nucleus pulposus-like cells
Li Ni et al.
SPINE JOURNAL (2014)
Human Mesenchymal Stem Cell Microvesicles for Treatment of Escherichia coli Endotoxin- Induced Acute Lung Injury in Mice
Ying-gang Zhu et al.
STEM CELLS (2014)
Mesenchymal stem cell-derived exosomes promote hepatic regeneration in drug-induced liver injury models
Cheau Yih Tan et al.
STEM CELL RESEARCH & THERAPY (2014)
Tumor necrosis factor and interleukin-1dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1
Jianru Wang et al.
ARTHRITIS AND RHEUMATISM (2013)
The therapeutic potential of mesenchymal stem cell-derived extracellular vesicles
Takeshi Katsuda et al.
PROTEOMICS (2013)
Toll-Like Receptor 4 (TLR4) Expression and Stimulation in a Model of Intervertebral Disc Inflammation and Degeneration
Neena E. Rajan et al.
SPINE (2013)
Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury
Fatih Arslan et al.
STEM CELL RESEARCH (2013)
Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Alleviate Liver Fibrosis
Tingfen Li et al.
STEM CELLS AND DEVELOPMENT (2013)
Exosomes Mediate the Cytoprotective Action of Mesenchymal Stromal Cells on Hypoxia-Induced Pulmonary Hypertension
Changjin Lee et al.
CIRCULATION (2012)
Mesenchymal stem cells injection in degenerated intervertebral disc: cell leakage may induce osteophyte formation
Gianluca Vadala et al.
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE (2012)
The Burden of Chronic Low Back Pain Clinical Comorbidities, Treatment Patterns, and Health Care Costs in Usual Care Settings
Mugdha Gore et al.
SPINE (2012)
Malignant Tumor Formation After Transplantation of Short-Term Cultured Bone Marrow Mesenchymal Stem Cells in Experimental Myocardial Infarction and Diabetic Neuropathy
Jin-Ok Jeong et al.
CIRCULATION RESEARCH (2011)
The Effect of Injection Volume on Disc Degeneration in a Rat Tail Model
Hua-jie Mao et al.
SPINE (2011)
Porcine Intervertebral Disc Repair Using Allogeneic Juvenile Articular Chondrocytes or Mesenchymal Stem Cells
Frank L. Acosta et al.
TISSUE ENGINEERING PART A (2011)
Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche
Ahmed Mohyeldin et al.
CELL STEM CELL (2010)
Functional delivery of viral miRNAs via exosomes
D. Michiel Pegtel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Mesenchymal Stem Cell-Derived Microvesicles Protect Against Acute Tubular Injury
Stefania Bruno et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)
The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
Beom Seok Park et al.
NATURE (2009)
Membrane vesicles as conveyors of immune responses
Clotilde Thery et al.
NATURE REVIEWS IMMUNOLOGY (2009)
The effect of relative needle diameter in puncture and sham injection animal models of degeneration
Dawn M. Elliott et al.
SPINE (2008)
Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium
Leo Timmers et al.
Stem Cell Research (2008)
Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells
Ivana Rosova et al.
STEM CELLS (2008)
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
Hadi Valadi et al.
NATURE CELL BIOLOGY (2007)
TLR signaling
T Kawai et al.
CELL DEATH AND DIFFERENTIATION (2006)
A novel rabbit model of mild, reproducible disc degeneration by an anulus needle puncture: Correlation between the degree of disc injury and radiological and histological appearances of disc degeneration
K Masuda et al.
SPINE (2005)
Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium
LB Balsam et al.
NATURE (2004)
Current understanding of cellular and molecular events in intervertebral disc degeneration: implications for therapy
AJ Freemont et al.
JOURNAL OF PATHOLOGY (2002)
Magnetic resonance classification of lumbar intervertebral disc degeneration
CWA Pfirrmann et al.
SPINE (2001)
Share Paper
