4.6 Article

Thrombolysis and thrombectomy in patients treated with dabigatran with acute ischemic stroke: Expert opinion

Journal

INTERNATIONAL JOURNAL OF STROKE
Volume 12, Issue 1, Pages 9-12

Publisher

SAGE PUBLICATIONS LTD
DOI: 10.1177/1747493016669849

Keywords

Ischemic stroke; thrombolysis; rt-PA; thrombectomy; dabigatran; idarucizumab

Funding

  1. Alberta Innovates [201300690] Funding Source: researchfish

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Systemic thrombolysis with rt-PA is contraindicated in patients with acute ischemic stroke anticoagulated with dabigatran. This expert opinion provides guidance on the use of the specific reversal agent idarucizumab followed by rt-PA and/or thrombectomy in patients with ischemic stroke pre-treated with dabigatran. The use of idarucizumab followed by rt-PA is covered by the label of both drugs.

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