4.3 Article

The Field Guide to 3D Printing in Optical Microscopy for Life Sciences

Journal

ADVANCED BIOLOGY
Volume 6, Issue 4, Pages -

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adbi.202100994

Keywords

3D printing; microscopy; open-sources; optics; super-resolution

Funding

  1. Gulbenkian Foundation
  2. European Research Council (ERC) under the European Union [101001332]
  3. European Molecular Biology Organization (EMBO) Installation Grant [EMBO-2020-IG-4734]
  4. Wellcome Trust [203276/Z/16/Z]
  5. Integrative Biology and Biomedicine PhD programme from Instituto Gulbenkian de Ciencia
  6. European Research Council (ERC) [101001332] Funding Source: European Research Council (ERC)
  7. Wellcome Trust [203276/Z/16/Z] Funding Source: Wellcome Trust

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The maker movement has brought 3D printing technology into optics labs, revolutionizing the field by improving accessibility and allowing rapid, low-cost prototyping. This approach fosters collaboration among researchers and promotes democratization of technology, extending the open-access concept from knowledge to technology.
The maker movement has reached the optics labs, empowering researchers to create and modify microscope designs and imaging accessories. 3D printing has a disruptive impact on the field, improving accessibility to fabrication technologies in additive manufacturing. This approach is particularly useful for rapid, low-cost prototyping, allowing unprecedented levels of productivity and accessibility. From inexpensive microscopes for education such as the FlyPi to the highly complex robotic microscope OpenFlexure, 3D printing is paving the way for the democratization of technology, promoting collaborative environments between researchers, as 3D designs are easily shared. This holds the unique possibility of extending the open-access concept from knowledge to technology, allowing researchers everywhere to use and extend model structures. Here, it is presented a review of additive manufacturing applications in optical microscopy for life sciences, guiding the user through this new and exciting technology and providing a starting point to anyone willing to employ this versatile and powerful new tool.

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