Journal
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Volume 512, Issue 2, Pages 360-365Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijpharm.2016.02.035
Keywords
Polypharmacy; Prescribing; Formulation; Older people; Clinical trials; Adherence
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Funding
- Dunhill Medical Trust [R298/0513]
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This paper focuses on the issue of polypharmacy in older people and potential pharmaceutical strategies to optimize the use of multiple medicines. Although polypharmacy has long been viewed negatively, increasing emphasis is being placed on the difference between appropriate and inappropriate polypharmacy. This is largely being driven by the increasing prevalence of multimorbidity and the use of evidence-based guidelines. In this paper, we outline a number of key considerations that are pertinent to optimizing polypharmacy, notably prescribing appropriate polypharmacy, pharmaceutical formulations, the involvement of older people in clinical trials and patient adherence. Crown Copyright (C) 2016 Published by Elsevier B.V. All rights reserved.
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