3.8 Review

Anticancer properties of arylchromenes and arylchromans: an overview

Journal

PHYSICAL SCIENCES REVIEWS
Volume -, Issue -, Pages -

Publisher

WALTER DE GRUYTER GMBH
DOI: 10.1515/psr-2021-0033

Keywords

arylchromans; arylchromenes; anticancer properties

Funding

  1. Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
  2. Fundacao de Amparo a Pesquisa do Estado de Minas Gerais (FAPEMIG)
  3. Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)
  4. Pro-Reitoria de Pesquisa da Universidade Federal de Minas Gerais (PRPqUFMG)
  5. CNPq research fellowship

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Cancer is a group of pathologies caused by cells dividing and multiplying uncontrollably, with chemotherapy being a main treatment approach. Arylchromenes and arylchromans, small molecules of natural or synthetic origin, are of great interest as potential therapeutic prototypes against cancer.
Cancers are a set of pathologies originated by cells that have the ability to divide and multiply uncontrollably, associated with the capacity to invade and colonize adjacent tissues. Chemotherapy is one of the main approaches of treatment for cancer patients. Despite of the numerous antineoplastic drugs available, cancer cannot be cured; particularly at the late stages deprived of any side effect. Arylchromenes and arylchromans are a group of small molecules, of natural or synthetic origin, of great interest as prototypes for the drug development, especially against cancer. In this chapter, we will present the antineoplastic activity studies of the most promising examples of these arylchromenes and arylchroman derivatives.

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