Journal
IDCASES
Volume 27, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.idcr.2022.e01428
Keywords
Dematiaceous; Mycosis; Coronavirus; COVID-19; Antifungal; Malaysia
Categories
Ask authors/readers for more resources
This article presents a case of a COVID-19 pneumonia patient in India who developed a 'true black fungus' infection. Despite antifungal therapy, the patient's condition deteriorated rapidly and resulted in death. The article also reviews reported cases of Exophiala dermatitidis fungemia in the past 5 years.
The second wave of the COVID-19 pandemic in India had brought with it a surge of 'black fungus' coinfection, which is a misnomer for mucormycosis. The present case illustrates the 'real black fungus' infection in a 50-year old male patient with COVID-19 pneumonia, who otherwise had no significant previous medical history. He was admitted on day 8 of COVID-19 illness and was intubated due to persistently low oxygen saturation. Blood cultures were positive for flask-shaped dematiaceous budding yeasts with pseudohyphae formation, which grew as brown-black fuzzy colonies on Sabouraud dextrose agar. The isolate was identified as Exophiala dermatitidis based on phenotypic characterization. Despite antifungal therapy with amphotericin B and itraconazole, the patient deteriorated rapidly and succumbed to acute respiratory distress syndrome and multiorgan failure. A review of reported cases of Exophiala dermatitidis fungemia over the last 5-years is discussed. (C) 2022 Published by Elsevier Ltd.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available