Journal
INTERNATIONAL JOURNAL OF NANOMEDICINE
Volume 12, Issue -, Pages 179-195Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/IJN.S124218
Keywords
photoacoustics; imaging; therapy; nanomaterials; nanomedicine
Funding
- National Natural Science Foundation of China [21575106]
- Scientific Research Foundation for Returned Scholars, Ministry of Education of China, Wenzhou City Science & Technology Bureau, China [Y20150084, Y20150085]
- Health and Family Planning Commission of Zhejiang Province, China [2015KYA159, 2016KYA143]
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Photoacoustic imaging (PAI) is an integrated biomedical imaging modality which combines the advantages of acoustic deep penetration and optical high sensitivity. It can provide functional and structural images with satisfactory resolution and contrast which could provide abundant pathological information for disease-oriented diagnosis. Therefore, it has found vast applications so far and become a powerful tool of precision nanomedicine. However, the investigation of PAI-based imaging nanomaterials is still in its infancy. This perspective article aims to summarize the developments in photoacoustic technologies and instrumentations in the past years, and more importantly, present a bright outlook for advanced PAI-based imaging nanomaterials as well as their emerging biomedical applications in nanomedicine. Current challenges and bottleneck issues have also been discussed and elucidated in this article to bring them to the attention of the readership.
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