Related references
Note: Only part of the references are listed.G6PD: A hub for metabolic reprogramming and redox signaling in cancer
Hung-Chi Yang et al.
BIOMEDICAL JOURNAL (2021)
Phytol Down-Regulates Expression of Some Cancer Stem Cell Markers and Decreases Side Population Proportion in Human Embryonic Carcinoma NCCIT Cells
Sara Soltanian et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2021)
PIKE-A promotes glioblastoma growth by driving PPP flux through increasing G6PD expression mediated by phosphorylation of STAT3
Mingming Sun et al.
BIOCHEMICAL PHARMACOLOGY (2021)
Integrative analyses of gene expression and chemosensitivity of patient-derived ovarian cancer spheroids link G6PD-driven redox metabolism to cisplatin chemoresistance
Kaoru Yamawaki et al.
CANCER LETTERS (2021)
Discovery and characterization of a novel glucose-6-phosphate dehydrogenase (G6PD) inhibitor via high-throughput screening
Zhongyuan Luo et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2021)
Regulation of Butyrate-Induced Resistance through AMPK Signaling Pathway in Human Colon Cancer Cells
Hee Young Yoo et al.
BIOMEDICINES (2021)
Butyrate Suppresses Glucose Metabolism of Colorectal Cancer Cells via GPR109a-AKT Signaling Pathway and Enhances Chemotherapy
Hong-Wei Geng et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2021)
Prebiotic Inulin and Sodium Butyrate Attenuate Obesity-Induced Intestinal Barrier Dysfunction by Induction of Antimicrobial Peptides
Julia Beisner et al.
FRONTIERS IN IMMUNOLOGY (2021)
Butyrate Decreases ICAM-1 Expression in Human Oral Squamous Cell Carcinoma Cells
Gabriel Leonardo Magrin et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
miR-613 suppresses migration and invasion in esophageal squamous cell carcinoma via the targeting of G6PD
Xiangyu Su et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2020)
G6PD facilitates clear cell renal cell carcinoma invasion by enhancing MMP2 expression through ROS-MAPK axis pathway
Qiao Zhang et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2020)
Aspirin and Its Potential Preventive Role in Cancer: An Umbrella Review
Yongxi Song et al.
FRONTIERS IN ENDOCRINOLOGY (2020)
Synergistic effect of graphene oxide and zoledronic acid for osteoporosis and cancer treatment
Gokcen Boran et al.
SCIENTIFIC REPORTS (2020)
Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer
Xiaoguang Liu et al.
NATURE CELL BIOLOGY (2020)
Targeting G6PD reverses paclitaxel resistance in ovarian cancer by suppressing GSTP1
Qi Feng et al.
BIOCHEMICAL PHARMACOLOGY (2020)
Suppression of G6PD induces the expression and bisecting GlcNAc-branched N-glycosylation of E-Cadherin to block epithelial-mesenchymal transition and lymphatic metastasis
Yifei Wang et al.
BRITISH JOURNAL OF CANCER (2020)
Wedelolactone facilitates Ser/Thr phosphorylation of NLRP3 dependent on PKA signalling to block inflammasome activation and pyroptosis
Hao Pan et al.
CELL PROLIFERATION (2020)
High-throughput screening suggests glutathione synthetase as an anti-tumor target of polydatin using human proteome chip
Peng Chen et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)
Zoledronic acid inhibits thyroid cancer stemness and metastasis by repressing M2-like tumor-associated macrophages induced Wnt/β-catenin pathway
Juan Lv et al.
LIFE SCIENCES (2020)
Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway
Yaodong Chen et al.
LIFE SCIENCES (2020)
Polydatin prevents bleomycin-induced pulmonary fibrosis by inhibiting the TGF-β/Smad/ERK signaling pathway
Yan-Lu Liu et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2020)
Glucose 6-phosphate dehydrogenase inhibition sensitizes melanoma cells to metformin treatment
Maria Florencia Arbe et al.
TRANSLATIONAL ONCOLOGY (2020)
Prognostic significance of G6PD expression and localization in lung adenocarcinoma
Ryo Nagashio et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2019)
Complex roles of the old drug aspirin in cancer chemoprevention and therapy
Hui Hua et al.
MEDICINAL RESEARCH REVIEWS (2019)
Zoledronic acid for the treatment of prostate cancer
Antoine Finianos et al.
EXPERT OPINION ON PHARMACOTHERAPY (2019)
Glucose-6-phosphate dehydrogenase blockade potentiates tyrosine kinase inhibitor effect on breast cancer cells through autophagy perturbation
Luigi Mele et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
RRx-001 followed by platinum plus etoposide in patients with previously treated small-cell lung cancer
Daniel Morgensztern et al.
BRITISH JOURNAL OF CANCER (2019)
4-hydroxyphenylpyruvate dioxygenase promotes lung cancer growth via pentose phosphate pathway (PPP) flux mediated by LKB1-AMPK/HDAC10/G6PD axis
Changliang Shan et al.
CELL DEATH & DISEASE (2019)
Wedelolactone alleviates doxorubicin-induced inflammation and oxidative stress damage of podocytes by IκK/IκB/NF-κB pathway
Zhu Mao-mao et al.
BIOMEDICINE & PHARMACOTHERAPY (2019)
Nitrite may serve as a combination partner and a biomarker for the anti-cancer activity of RRx-001
Selma Cirrik et al.
BIORHEOLOGY (2019)
Butyrate mediated regulation of RNA binding proteins in the post-transcriptional regulation of inflammatory gene expression
Aydan Torun et al.
CELLULAR SIGNALLING (2019)
Phytol as an anticarcinogenic and antitumoral agent: An in vivo study in swiss mice with DMBA-Induced breast cancer
Marcus Vinicius Oliveira Barros de Alencar et al.
IUBMB LIFE (2019)
Transcription Factor YY1 Promotes Cell Proliferation by Directly Activating the Pentose Phosphate Pathway
Shourong Wu et al.
CANCER RESEARCH (2018)
G6PD as a predictive marker for glioma risk, prognosis and chemosensitivity
Chin-An Yang et al.
JOURNAL OF NEURO-ONCOLOGY (2018)
A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo
Luigi Mele et al.
CELL DEATH & DISEASE (2018)
Brief report: RRx-001 is a c-Myc inhibitor that targets cancer stem cells
Bryan Oronsky et al.
Oncotarget (2018)
The role of miR-122 in the dysregulation of glucose-6-phosphate dehydrogenase (G6PD) expression in hepatocellular cancer
Juan M. Barajas et al.
SCIENTIFIC REPORTS (2018)
Aspirin acts in esophageal cancer: a brief review
Weiming Hao et al.
JOURNAL OF THORACIC DISEASE (2018)
Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells
Lin Yang et al.
REDOX BIOLOGY (2018)
Association of Phytol with Toxic and Cytotoxic Activities in an Antitumoral Perspective: A Meta-Analysis and Systemic Review
Marcus V. O. B. Alencar et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2018)
Modulation of G6PD affects bladder cancer via ROS accumulation and the AKT pathway in vitro
Xiaoyi Chen et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2018)
MicroRNA-206 suppresses proliferation and predicts poor prognosis of HR-HPV-positive cervical cancer cells by targeting G6PD
Jinpeng Cui et al.
ONCOLOGY LETTERS (2018)
Downregulation of glucose-6-phosphate dehydrogenase by microRNA-1 inhibits the growth of pituitary tumor cells
Chao He et al.
ONCOLOGY REPORTS (2018)
Elevated G6PD expression contributes to migration and invasion of hepatocellular carcinoma cells by inducing epithelial-mesenchymal transition
Ming Lu et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2018)
Wedelolactone Acts as Proteasome Inhibitor in Breast Cancer Cells
Tereza Nehybova et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Polydatin inhibits cell proliferation and induces apoptosis in laryngeal cancer and HeLa cells via suppression of the PDGF/AKT signaling pathway
Haixia Li et al.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2017)
ID1 promotes hepatocellular carcinoma proliferation and confers chemoresistance to oxaliplatin by activating pentose phosphate pathway
Xin Yin et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2017)
High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells
L. Poulain et al.
LEUKEMIA (2017)
Disrupting G6PD-mediated Redox homeostasis enhances chemosensitivity in colorectal cancer
H-Q Ju et al.
ONCOGENE (2017)
PAK4 regulates G6PD activity by p53 degradation involving colon cancer cell growth
Xiumei Zhang et al.
CELL DEATH & DISEASE (2017)
Polo-like kinase 1 coordinates biosynthesis during cell cycle progression by directly activating pentose phosphate pathway
Xiaoyu Ma et al.
NATURE COMMUNICATIONS (2017)
G6PD promotes renal cell carcinoma proliferation through positive feedback regulation of p-STAT3
Qiao Zhang et al.
ONCOTARGET (2017)
Differential biological effects of dehydroepiandrosterone (DHEA) between mouse (B16F10) and human melanoma (BLM) cell lines
Kumud Joshi et al.
DERMATO-ENDOCRINOLOGY (2017)
Phytol induces ROS mediated apoptosis by induction of caspase 9 and 3 through activation of TRAIL, FAS and TNF receptors and inhibits tumor progression factor Glucose 6 phosphate dehydrogenase in lung carcinoma cell line (A549)
Parth Thakor et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
Dehydroepiandrosterone (DHEA) Feeding Protects Liver Steatosis in Obese Breast Cancer Rat Model
Reza Hakkak et al.
SCIENTIA PHARMACEUTICA (2017)
Glucose 6-phosphate dehydrogenase and the kidney
Netanya Y. Spencer et al.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2017)
BAG3 elevation inhibits cell proliferation via direct interaction with G6PD in hepatocellular carcinomas
De-Hui Kong et al.
ONCOTARGET (2016)
Effects of G6PD activity inhibition on the viability, ROS generation and mechanical properties of cervical cancer cells
Zishui Fang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)
Aspirin inhibits glucose-6-phosphate dehydrogenase activity in HCT 116 cells through acetylation: Identification of aspirin-acetylated sites
Guoqiang Ai et al.
MOLECULAR MEDICINE REPORTS (2016)
miR-1 inhibits progression of high-risk papillomavirus-associated human cervical cancer by targeting G6PD
Tao Hu et al.
ONCOTARGET (2016)
SIRT2 activates G6PD to enhance NADPH production and promote leukaemia cell proliferation
Shuang-Nian Xu et al.
SCIENTIFIC REPORTS (2016)
Wedelolactone Enhances Osteoblastogenesis but Inhibits Osteoclastogenesis through Sema3A/NRP1/PlexinA1 Pathway
Yan-Qiu Liu et al.
FRONTIERS IN PHARMACOLOGY (2016)
HSPB1 Enhances SIRT2-Mediated G6PD Activation and Promotes Glioma Cell Proliferation
Hongxing Ye et al.
PLOS ONE (2016)
SMYD1 and G6PD modulation are critical events for miR-206-mediated differentiation of rhabdomyosarcoma
Davide Martino Coda et al.
CELL CYCLE (2015)
Glucose-6-phosphate dehydrogenase expression is correlated with poor clinical prognosis in esophageal squamous cell carcinoma
Xin Wang et al.
EJSO (2015)
Zoledronic acid inhibits the pentose phosphate pathway through attenuating the Ras-TAp73-G6PD axis in bladder cancer cells
Xiaolin Wang et al.
MOLECULAR MEDICINE REPORTS (2015)
O-GlcNAcylation of G6PD promotes the pentose phosphate pathway and tumor growth
Xiongjian Rao et al.
NATURE COMMUNICATIONS (2015)
Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress
Yi-Ping Wang et al.
EMBO JOURNAL (2014)
PTEN antagonises Tcl1/hnRNPK-mediated G6PD pre-mRNA splicing which contributes to hepatocarcinogenesis
Xuehui Hong et al.
GUT (2014)
Computational determination of binding structures and free energies of glucose 6-phosphate dehydrogenase with novel steroid inhibitors
Zhi-Bo Zhao et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2014)
Butyrate impairs atherogenesis by reducing plaque inflammation and vulnerability and decreasing NFκB activation
E. C. Aguilar et al.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES (2014)
6-Phosphogluconate dehydrogenase regulates tumor cell migration in vitro by regulating receptor tyrosine kinase c-Met
Barden Chan et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Aspirin acetylates glucose 6 phosphate dehydrogenase and inhibits its activity in colon cancer cells
Guoqiang Ai et al.
CANCER RESEARCH (2013)
A critical role of glucose-6-phosphate dehydrogenase in TAp73-mediated cell proliferation
Peng Jiang et al.
CELL CYCLE (2013)
TAp73 enhances the pentose phosphate pathway and supports cell proliferation
Wenjing Du et al.
NATURE CELL BIOLOGY (2013)
Identification and Characterization of Novel Human Glucose-6-Phosphate Dehydrogenase Inhibitors
Janina Preuss et al.
JOURNAL OF BIOMOLECULAR SCREENING (2013)
Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence
Vikas P. Sukhatme et al.
FEBS LETTERS (2012)
Overexpression of G6PD is associated with poor clinical outcome in gastric cancer
Jixu Wang et al.
TUMOR BIOLOGY (2012)
Modulation of doxorubicin resistance by the glucose-6-phosphate dehydrogenase activity
Manuela Polimeni et al.
BIOCHEMICAL JOURNAL (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
The Microbiome and Butyrate Regulate Energy Metabolism and Autophagy in the Mammalian Colon
Dallas R. Donohoe et al.
CELL METABOLISM (2011)
ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair
Claudia Cosentino et al.
EMBO JOURNAL (2011)
p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase
Peng Jiang et al.
NATURE CELL BIOLOGY (2011)
Oligomerization studies of Leuconostoc mesenteroides G6PD activity after SDS-PAGE and blotting
S. Ravera et al.
MOLECULAR BIOLOGY (2010)
Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1
Katrin Duevel et al.
MOLECULAR CELL (2010)
A New G6PD Knockdown Tumor-Cell Line with Reduced Proliferation and Increased Susceptibility to Oxidative Stress
Danyi Li et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2009)
Protective role of 1α, 25-dihydroxyvitamin D3 against oxidative stress in nonmalignant human prostate epithelial cells
Bo-Ying Bao et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
Gluclose-6-phosphate dehydrogenase deficiency
M. D. Cappellini et al.
LANCET (2008)
What is the role of the second structural NADP+-binding site in human glucose 6-phosphate dehydrogenase?
Xiao-Tao Wang et al.
PROTEIN SCIENCE (2008)
Radiosensitization by 6-aminonicotinamide and 2-deoxy-D-glucose in human cancer cells
R Varshney et al.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2005)
Structural studies of glucose-6-phosphate and NADP+ binding to human glucose-6-phosphate dehydrogenase
M Kotaka et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2005)
Dehydroepiandrosterone, glucose-6-phosphate dehydrogenase, and longevity
AG Schwartz et al.
AGEING RESEARCH REVIEWS (2004)
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
RJ Shaw et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Transcriptional activities of nuclear SREBP-1a,-1c, and-2 to different target promoters of lipogenic and cholesterogenic genes
M Amemiya-Kudo et al.
JOURNAL OF LIPID RESEARCH (2002)
Human glucose-6-phosphate dehydrogenase:: the crystal structure reveals a structural NADP+ molecule and provides insights into enzyme deficiency
SWN Au et al.
STRUCTURE (2000)