4.6 Article

Vitamin E: Where Are We Now in Vascular Diseases?

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Interventional study with vitamin E in cardiovascular disease and meta-analysis

Francesco Violi et al.

Summary: Vitamin E possesses antioxidant and anti-inflammatory properties that have an impact on atherosclerosis and thrombus formation, but intervention trials have yielded negative results.

FREE RADICAL BIOLOGY AND MEDICINE (2022)

Article Biochemistry & Molecular Biology

Lipid oxidation that is, and is not, inhibited by vitamin E: Consideration about physiological functions of vitamin E

Etsuo Niki

Summary: Vitamin E plays a crucial role in inhibiting unregulated lipid peroxidation by scavenging lipid peroxyl radicals, although it is not efficient in scavenging certain types of free radicals. Free radical-mediated lipid peroxidation is the major pathway of lipid oxidation in humans. Together with other antioxidants like vitamin C, vitamin E helps maintain human health and prevent diseases by inhibiting detrimental oxidation of biological molecules.

FREE RADICAL BIOLOGY AND MEDICINE (2021)

Article Biochemistry & Molecular Biology

Vitamin E as an essential micronutrient for human health: Common, novel, and unexplored dietary sources

Fereidoon Shahidi et al.

Summary: Vitamin E is a group of vitamers that act as antioxidants in prevention and treatment of diseases, with common edible oils being the main source. Specialty and underutilized oils are emerging as novel sources of this important nutrient, requiring further studies on their tocotrienol content for better understanding of biological functions.

FREE RADICAL BIOLOGY AND MEDICINE (2021)

Article Biochemistry & Molecular Biology

Vitamin E: How much is enough, too much and why!

Maret G. Traber et al.

Summary: This narrative review focuses on the structures, functions, biological determinants, and deficiency symptoms of vitamin E in humans, discussing the mechanisms for alpha-T tissue enrichment, potential new biomarkers, pharmacokinetic data, and approaches to evaluate alpha-T dietary requirements. The possible role of alpha-T supplements in delaying chronic diseases and the evaluation of vitamin E safety are also considered in this review.

FREE RADICAL BIOLOGY AND MEDICINE (2021)

Article Biochemistry & Molecular Biology

Vitamin E research: Past, now and future

Regina Brigelius-Flohe

Summary: The early history of vitamin E, its discovery and chemical synthesis, as well as the development of the concept of its antioxidant properties are recounted. Recent research has cast doubt on this hypothesis, including the effects of vitamin E on enzyme activities, signaling cascades, gene expression, and biomembrane structure. Overall, our knowledge of vitamin E's mechanism of action remains incomplete, with discussions on its metabolism, bioactivity of its metabolites, and implications for future clinical trials.

FREE RADICAL BIOLOGY AND MEDICINE (2021)

Review Biochemistry & Molecular Biology

Vitamin E: Regulatory Role on Signal Transduction

Jean-Marc Zingg

IUBMB LIFE (2019)

Review Biochemistry & Molecular Biology

Vitamin E - The Next 100 Years

Fatemeh Khadangi et al.

IUBMB LIFE (2019)

Review Biochemistry & Molecular Biology

Many tocopherols, one vitamin E

Angelo Azzi

MOLECULAR ASPECTS OF MEDICINE (2018)

Article Nutrition & Dietetics

Do dry roasting, lightly salting nuts affect their cardioprotective properties and acceptability?

Siew Ling Tey et al.

EUROPEAN JOURNAL OF NUTRITION (2017)

Review Biochemistry & Molecular Biology

Vitamin E: Emerging aspects and new directions

Francesco Galli et al.

FREE RADICAL BIOLOGY AND MEDICINE (2017)

Article Biochemistry & Molecular Biology

Induction of VEGF Expression by Alpha-Tocopherol and Alpha-Tocopheryl Phosphate via PI3Kγ/PKB and hTAP1/SEC14L2-Mediated Lipid Exchange

Jean-Marc Zingg et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2015)

Review Biochemistry & Molecular Biology

Regulatory metabolites of vitamin E and their putative relevance for atherogenesis

Maria Wallert et al.

REDOX BIOLOGY (2014)

Article Nutrition & Dietetics

Vitamin E Trafficking in Neurologic Health and Disease

Lynn Ulatowski et al.

Annual Review of Nutrition (2013)

Article Nutrition & Dietetics

A metabolomic investigation of the effects of vitamin E supplementation in humans

Max Wong et al.

NUTRITION & METABOLISM (2012)

Article Nutrition & Dietetics

Foods, Fortificants, and Supplements: Where Do Americans Get Their Nutrients?

Victor L. Fulgoni et al.

JOURNAL OF NUTRITION (2011)

Article Multidisciplinary Sciences

Promotion of plasma membrane repair by vitamin E

Amber C. Howard et al.

NATURE COMMUNICATIONS (2011)

Article Biochemistry & Molecular Biology

Modulation of gene expression by α-tocopherol and α-tocopheryl phosphate in THP-1 monocytes

Jean-Marc Zingg et al.

FREE RADICAL BIOLOGY AND MEDICINE (2010)

Review Biochemistry & Molecular Biology

Vitamin E: The shrew waiting to be tamed

Regina Brigelius-Flohe

FREE RADICAL BIOLOGY AND MEDICINE (2009)

Article Medicine, General & Internal

Vitamins E and C in the Prevention of Cardiovascular Disease in Men The Physicians' Health Study II Randomized Controlled Trial

Howard D. Sesso et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2008)

Article Cardiac & Cardiovascular Systems

Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis

Judith C. Sluimer et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2008)

Article Medicine, General & Internal

Vitamin E in the primary prevention of cardiovascular disease and cancer - The Women's Health Study: A randomized controlled trial

IM Lee et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2005)

Review Medicine, General & Internal

Meta-analysis: High-dosage vitamin E supplementation may increase all-cause mortality

ER Miller et al.

ANNALS OF INTERNAL MEDICINE (2005)

Article Cardiac & Cardiovascular Systems

Inhibition of platelet adherence to mononuclear cells by α-tocopherol -: Role of P-selectin

T Murohara et al.

CIRCULATION (2004)

Review Medical Laboratory Technology

Vitamins in human arteriosclerosis with emphasis on vitamin C and vitamin E

N Abudu et al.

CLINICA CHIMICA ACTA (2004)

Article Pharmacology & Pharmacy

Vitamin E activates gene expression via the pregnane X receptor

N Landes et al.

BIOCHEMICAL PHARMACOLOGY (2003)

Review Cardiac & Cardiovascular Systems

The oxidative modification hypothesis of atherosclerosis: Does it hold for humans?

JL Witztum et al.

TRENDS IN CARDIOVASCULAR MEDICINE (2001)

Review Biochemistry & Molecular Biology

Vitamin E: non-antioxidant roles

A Azzi et al.

PROGRESS IN LIPID RESEARCH (2000)