Introducing Graphene-Indium Oxide Electrochemical Sensor for Detecting Ethanol in Aqueous Samples with CCD-RSM Optimization

There is significant demand for portable sensors that can deliver selective and sensitive measurement of ethanol on-site. Such sensors have application across many industries, including clinical and forensic work as well as agricultural and environmental analysis. Here, we report a new graphene-indium oxide electrochemical sensor for the determination of ethanol in aqueous samples. Graphene layers were functionalised by anchoring In2O3 to its surface and the developed composite was used as a selective electrochemical sensor for sensing ethanol through cyclic voltammetry. The detection limit of the sensor was 0.068 mol/L and it showed a linear response to increasing ethanol in the environment up to 1.2 mol/L. The most significant parameters involved and their interactions in the response of the sensor and optimization procedures were studied using a four-factor central composite design (CCD) combined with response surface modelling (RSM). The sensor was applied in the detection of ethanol in authentic samples.

Automated summary

A new graphene-indium oxide electrochemical sensor was developed for selective and sensitive measurement of ethanol in aqueous samples. The sensor showed a linear response to increasing ethanol and had a detection limit of 0.068 mol/L. The study also involved optimization procedures using central composite design and response surface modeling.