Journal
FRONTIERS IN NUTRITION
Volume 8, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fnut.2021.791899
Keywords
acute wound; chronic wound; complementary and alternative medicine; infection; phytochemicals; polyphenols
Categories
Funding
- Ramaiah Institute of Technology, MSRIT Post, Bengaluru
- Ramaiah Medical College and Hospitals, MSRIT Post, Bengaluru
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Wound healing is a complicated biological process that is influenced by an individual's health status and other factors. Current treatment options for chronic wounds are limited, and the use of complementary and alternative medicine in wound management is still being explored.
Although the word wound sounds like a simple injury to tissue, individual's health status and other inherent factors may make it very complicated. Hence, wound healing has gained major attention in the healthcare. The biology wound healing is precise and highly programmed, through phases of hemostasis, inflammation, proliferation and remodeling. Current options for wound healing which includes, use of anti-microbial agents, healing promoters along with application of herbal and natural products. However, there is no efficient evidence-based therapy available for specific chronic wounds that can result in definitive clinical outcomes. Under co-morbid conditions, chronic would poses numerous challenges. Use of Complementary and Alternative Medicines (CAMs) in health care sector is increasing and its applications in wound management remains like to separate the diamonds from ore. Attempts have been made to understand the wound at the molecular level, mainly through the analysis of signature genes and the influence of several synthetic and natural molecules on these. We have outlined a review of challenges in chronic wound healing and the role of CAMs in chronic wound management. The main focus is on the applications and limitations of currently available treatment options for a non-healing wound and the best possible alternates to consider. This information generates broader knowledge on challenges in chronic wound healing, which can be further addressed using multidisciplinary approach and combination therapies.
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