4.6 Review

Nuclear Molecular Imaging of Cardiac Remodeling after Myocardial Infarction

Journal

PHARMACEUTICALS
Volume 15, Issue 2, Pages -

Publisher

MDPI
DOI: 10.3390/ph15020183

Keywords

myocardial infarction; cardiac remodeling; inflammation; angiogenesis; fibrosis

Funding

  1. Deutsche Forschungsgemeinschaft (DFG) [VA 1183/2-1]
  2. Open Access Publication Fund of the University of Duisburg-Essen

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Molecular imaging technologies play a vital role in the detection and treatment of cardiovascular disease, providing unique insights into pathobiological processes and enabling personalized therapy.
The role of molecular imaging technologies in detecting, evaluating, and monitoring cardiovascular disease and their treatment is expanding rapidly. Gradually replacing the conventional anatomical or physiological approaches, molecular imaging strategies using biologically targeted markers provide unique insight into pathobiological processes at molecular and cellular levels and allow for cardiovascular disease evaluation and individualized therapy. This review paper will discuss currently available and developing molecular-based single-photon emission computed tomography (SPECT) and positron emission tomography (PET) imaging strategies to evaluate postinfarction cardiac remodeling. These approaches include potential targeted methods of evaluating critical biological processes, such as inflammation, angiogenesis, and scar formation.

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