Journal
JOURNAL OF PERSONALIZED MEDICINE
Volume 12, Issue 2, Pages -Publisher
MDPI
DOI: 10.3390/jpm12020297
Keywords
diagnosis; gastrointestinal stromal tumor; gastric subepithelial tumor; stomach
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This study aimed to predict the diagnosis of gastric subepithelial tumors (GSETs) through a retrospective review. The results showed that age, hemoglobin levels, and computed tomography results can predict the risk of GISTs.
Gastrointestinal stromal tumors (GISTs), leiomyomas, and schwannomas are the most common gastric subepithelial tumors (GSETs) with similar endoscopic findings. Preoperative prediction of GSETs is difficult. This study analyzed and predicted GSET diagnosis through a retrospective review of 395 patients who underwent surgical resection of GISTs, leiomyomas, and schwannomas measuring 2-10 cm. GSETs were divided by size (group 2-5, >2 and <= 5 cm; group 5-10, >5 and <= 10 cm) for analysis. Demographics, clinical symptoms, and images were analyzed. A recursive partitioning analysis (RPA) was used to identify optimal classifications for specific GSET diagnoses. GIST patients were relatively older than other patients. Both groups had higher proportions of UGI bleeding, lower hemoglobin (Hb) levels, and a higher ratio of necrosis on their computed tomography (CT) scans. The RPA tree showed that (a) age <= 55, Hb >= 10.7, and CT necrosis; (b) age <= 55 and Hb < 10.7; (c) age >55 and Hb < 12.9; and (d) age >55 and CT hetero-/homogeneity can predict high GIST risk in group 2-5. Positive or negative CT necrosis, with age >55, can predict high GIST risk in group 5-10. GIST patients were older and presented with low Hb levels and tumor necrosis. In RPA, the accuracy reached 85% and 89% in groups 2-5 and 5-10, respectively.
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