Journal
JOURNAL OF PERSONALIZED MEDICINE
Volume 11, Issue 12, Pages -Publisher
MDPI
DOI: 10.3390/jpm11121315
Keywords
brief psychiatric rating scale; electroconvulsive therapy; mood disorders; quantitative electroencephalogram; schizophrenia
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The study indicates that an increase in alpha-band spectral power after acute ECT is associated with improvement in patients' emotional and mental states. Therefore, the increase in spectral power of the alpha band can serve as an objective indicator of the treatment effect of ECT.
The results of quantitative electroencephalography (qEEG) studies on electroconvulsive therapy (ECT) have been inconsistent, and indicators of the efficacy of ECT have not been clearly identified. In this study, we examined whether qEEG could be used as an indicator of the effect of ECT by measuring it during the course of treatment. We analyzed qEEG data before and after acute-phase ECT in 18 patients with schizophrenia, mood disorders, and other psychiatric disorders. We processed the qEEG data and compared the spectral power between the data acquired before and after ECT. The spectral power increased significantly after ECT in the delta, theta, and alpha bands. There was a strong significant correlation between the increase in the spectral power of the alpha band after acute ECT and improvement in the Brief Psychiatric Rating Scale score. Our results suggest that an increase in the alpha-band spectral power may be useful as an objective indicator of the treatment effect of acute ECT.
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