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Suppression of pancreatic tumor growth by combination chemotherapy with sulindac and LC-1 is associated with cyclin D1 inhibition in vivo
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MOLECULAR CANCER THERAPEUTICS (2007)
Parthenolide protects human lens epithelial cells from oxidative stress-induced apoptosis via inhibition of activation of caspase-3 and caspase-9
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CELL RESEARCH (2007)
Parthenolide-induced apoptosis in multiple myeloma cells involves reactive oxygen species generation and cell sensitivity depends on catalase activity
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APOPTOSIS (2006)
Restoring chemotherapy and hormone therapy sensitivity by parthenolide in a xenograft hormone refractory prostate cancer model
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PROSTATE (2006)
Parthenolide modulates the NF-κB-mediated inflammatory responses in experimental atherosclerosis
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ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)
Chemotherapy resistance of glioblastoma stem cells
A. Eramo et al.
CELL DEATH AND DIFFERENTIATION (2006)
Parthenolide cooperates with NS398 to inhibit growth of human hepatocellular carcinoma cells through effects on apoptosis and G0-G1 cell cycle arrest
Matthew C. Ralstin et al.
MOLECULAR CANCER RESEARCH (2006)
Suppressive effects of dehydroepiandrosterone and the nuclear factor-κB inhibitor parthenolide on corticotroph tumor cell growth and function in vitro and in vivo
T Taguchi et al.
JOURNAL OF ENDOCRINOLOGY (2006)
The sesquiterpene lactone parthenolide induces selective apoptosis of B-chronic lymphocytic leukemia cells in vitro
A. J. Steele et al.
LEUKEMIA (2006)
Parthenolide sensitizes ultraviolet (UV)-B-induced apoptosis via protein kinase C-dependent pathways
YK Won et al.
CARCINOGENESIS (2005)
Susceptibility of cholangiocarcinoma cells to parthenolide-induced apoptosis
JH Kim et al.
CANCER RESEARCH (2005)
The sesquiterpene lactone parthenolide in combination with docetaxel reduces metastasis and improves survival in a xenograft model of breast cancer
CJ Sweeney et al.
MOLECULAR CANCER THERAPEUTICS (2005)
Dual role of the anti-inflammatory sesquiterpene lactone: regulation of life and death by parthenolide
M Li-Weber et al.
CELL DEATH AND DIFFERENTIATION (2005)
Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase
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ONCOGENE (2004)
Phase I dose escalation trial of feverfew with standardized doses of parthenolide in patients with cancer
EA Curry et al.
INVESTIGATIONAL NEW DRUGS (2004)
Suppressed NF-κB and sustained JNK activation contribute to the sensitization effect of parthenolide to TNF-α-induced apoptosis in human cancer cells
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CARCINOGENESIS (2004)
Sesquiterpene lactone parthenolide blocks lipopolysaccharide-induced osteolysis through the suppression of NF-κB activity
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JOURNAL OF BONE AND MINERAL RESEARCH (2004)
NF-κB inhibition markedly enhances sensitivity of resistant breast cancer tumor cells to tamoxifen
LA deGraffenried et al.
ANNALS OF ONCOLOGY (2004)
Critical roles of intracellular thiols and calcium in parthenolide-induced apoptosis in human colorectal cancer cells
S Zhang et al.
CANCER LETTERS (2004)
Cell Cycle Effects and Caspase-Dependent and Independent Death of HL-60 and Jurkat Cells Treated with the Inhibitor of NF-kappa B Parthenolide
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Oxidative stress-mediated apoptosis - The anticancer effect of the sesquiterpene lactone parthenolide
J Wen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IκB kinase
BHB Kwok et al.
CHEMISTRY & BIOLOGY (2001)
Parthenolide inhibits activation of signal transducers and activators of transcription (STATs) induced by cytokines of the IL-6 family
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
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