Related references
Note: Only part of the references are listed.Enhanced homology-directed repair for highly efficient gene editing in hematopoietic stem/progenitor cells
Suk See De Ravin et al.
BLOOD (2021)
Cas9-AAV6 gene correction of beta-globin in autologous HSCs improves sickle cell disease erythropoiesis in mice
Adam C. Wilkinson et al.
NATURE COMMUNICATIONS (2021)
A Targeted and Tuneable DNA Damage Tool Using CRISPR/Cas9
Ioannis Emmanouilidis et al.
BIOMOLECULES (2021)
Democratising deep learning for microscopy with ZeroCostDL4Mic
Lucas von Chamier et al.
NATURE COMMUNICATIONS (2021)
Automated Analysis of Fluorescence Kinetics in Single-Molecule Localization Microscopy Data Reveals Protein Stoichiometry
Alon Saguy et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2021)
CRISPECTOR provides accurate estimation of genome editing translocation and off-target activity from comparative NGS data
Ido Amit et al.
NATURE COMMUNICATIONS (2021)
Using Synthetically Engineered Guide RNAs to Enhance CRISPR Genome Editing Systems in Mammalian Cells
Daniel Allen et al.
FRONTIERS IN GENOME EDITING (2021)
Accurate and rapid background estimation in single-molecule localization microscopy using the deep neural network BGnet
Leonhard Mockl et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Specificity profiling of CRISPR system reveals greatly enhanced off-target gene editing
Yao Wang et al.
SCIENTIFIC REPORTS (2020)
Three-dimensional localization microscopy in live flowing cells
Lucien E. Weiss et al.
NATURE NANOTECHNOLOGY (2020)
Increasing CRISPR Efficiency and Measuring Its Specificity in HSPCs Using a Clinically Relevant System
Jenny Shapiro et al.
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2020)
CHANGE-seq reveals genetic and epigenetic effects on CRISPR-Cas9 genome-wide activity
Cicera R. Lazzarotto et al.
NATURE BIOTECHNOLOGY (2020)
DeepSTORM3D: dense 3D localization microscopy and PSF design by deep learning
Elias Nehme et al.
NATURE METHODS (2020)
In Situ Detection of Complex DNA Damage Using Microscopy: A Rough Road Ahead
Zacharenia Nikitaki et al.
CANCERS (2020)
Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response
Giulia Schiroli et al.
CELL STEM CELL (2019)
Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination
Renata M. Martin et al.
CELL STEM CELL (2019)
Increasing the specificity of CRISPR systems with engineered RNA secondary structures
D. Dewran Kocak et al.
NATURE BIOTECHNOLOGY (2019)
Gene correction for SCID-X1 in long-term hematopoietic stem cells
Mara Pavel-Dinu et al.
NATURE COMMUNICATIONS (2019)
CRISPR-mediated live imaging of genome editing and transcription
Haifeng Wang et al.
SCIENCE (2019)
Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq
Beeke Wienert et al.
SCIENCE (2019)
Partial DNA-guided Cas9 enables genome editing with reduced off-target activity
Hao Yin et al.
NATURE CHEMICAL BIOLOGY (2018)
CRISPR/Cas9 genome editing in human hematopoietic stem cells
Rasmus O. Bak et al.
NATURE PROTOCOLS (2018)
Incorporation of bridged nucleic acids into CRISPR RNAs improves Cas9 endonuclease specificity
Christopher R. Cromwell et al.
NATURE COMMUNICATIONS (2018)
Deep-STORM: super-resolution single-molecule microscopy by deep learning
Elias Nehme et al.
OPTICA (2018)
Rapidly inducible Cas9 and DSB-ddPCR to probe editing kinetics
John C. Rose et al.
NATURE METHODS (2017)
Mapping the genomic landscape of CRISPR-Cas9 cleavage
Peter Cameron et al.
NATURE METHODS (2017)
CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR Cas9 nuclease off-targets
Shengdar Q. Tsai et al.
NATURE METHODS (2017)
Identification of the elementary structural units of the DNA damage response
Francesco Natale et al.
NATURE COMMUNICATIONS (2017)
Potential pitfalls of CRISPR/Cas9-mediated genome editing
Rongxue Peng et al.
FEBS JOURNAL (2016)
CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells
Daniel P. Dever et al.
NATURE (2016)
Treating Immunodeficiency through HSC Gene Therapy
Claire Booth et al.
TRENDS IN MOLECULAR MEDICINE (2016)
Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting
Andrew J. Aguirre et al.
CANCER DISCOVERY (2016)
How specific is CRISPR/Cas9 really?
Henriette O'Geen et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2015)
Imaging Flow Cytometry as a Sensitive Tool to Detect Low-Dose-Induced DNA Damage by Analyzing 53BP1 and γH2AX Foci in Human Lymphocytes
Matus Durdik et al.
CYTOMETRY PART A (2015)
Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells
Ayal Hendel et al.
NATURE BIOTECHNOLOGY (2015)
Multiple facets of histone variant H2AX: a DNA double-strand-break marker with several biological functions
Valentina Turinetto et al.
NUCLEIC ACIDS RESEARCH (2015)
Adeno-associated virus inverted terminal repeats stimulate gene editing
M. L. Hirsch
GENE THERAPY (2015)
Insight into the Mechanism of Inhibition of Adeno-Associated Virus by the Mre11/Rad50/Nbs1 Complex
Thomas B. Lentz et al.
JOURNAL OF VIROLOGY (2015)
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
Shengdar Q. Tsai et al.
NATURE BIOTECHNOLOGY (2015)
A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
Suhas S. P. Rao et al.
CELL (2014)
Topologically associating domains are stable units of replication-timing regulation
Benjamin D. Pope et al.
NATURE (2014)
CTCF: an architectural protein bridging genome topology and function
Chin-Tong Ong et al.
NATURE REVIEWS GENETICS (2014)
Cas9 as a versatile tool for engineering biology
Prashant Mali et al.
NATURE METHODS (2013)
ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
Thomas Gaj et al.
TRENDS IN BIOTECHNOLOGY (2013)
DNA Damage Sensing by the ATM and ATR Kinases
Alexandre Marechal et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
RNase H-dependent PCR (rhPCR): improved specificity and single nucleotide polymorphism detection using blocked cleavable primers
Joseph R. Dobosy et al.
BMC BIOTECHNOLOGY (2011)
Meganucleases and Other Tools for Targeted Genome Engineering: Perspectives and Challenges for Gene Therapy
George Silva et al.
CURRENT GENE THERAPY (2011)
More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance
Jiri Lukas et al.
NATURE CELL BIOLOGY (2011)
TAL Effectors: Customizable Proteins for DNA Targeting
Adam J. Bogdanove et al.
SCIENCE (2011)
Metadata matters: access to image data in the real world
Melissa Linkert et al.
JOURNAL OF CELL BIOLOGY (2010)
Adeno-Associated Virus Replication Induces a DNA Damage Response Coordinated by DNA-Dependent Protein Kinase
Rachel A. Schwartz et al.
JOURNAL OF VIROLOGY (2009)
Immunofluorescence imaging of DNA damage response proteins: Optimizing protocols for super-resolution microscopy
Brian T. Bennett et al.
METHODS (2009)
MOLECULAR ORIGINS OF CANCER DNA Damage, Aging, and Cancer
Jan H. J. Hoeijmakers
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Attenuation of Zinc Finger Nuclease Toxicity by Small-Molecule Regulation of Protein Levels
Shondra M. Pruett-Miller et al.
PLOS GENETICS (2009)
An improved zinc-finger nuclease architecture for highly specific genome editing
Jeffrey C. Miller et al.
NATURE BIOTECHNOLOGY (2007)
Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair
Elijahu Berkovich et al.
NATURE CELL BIOLOGY (2007)
Ultra-high resolution imaging by fluorescence photoactivation localization microscopy
Samuel T. Hess et al.
BIOPHYSICAL JOURNAL (2006)
Host cell DNA repair pathways in adeno-associated viral genome processing
Vivian W. Choi et al.
JOURNAL OF VIROLOGY (2006)
Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)
Michael J. Rust et al.
NATURE METHODS (2006)
Imaging intracellular fluorescent proteins at nanometer resolution
Eric Betzig et al.
SCIENCE (2006)
Gene targeting using zinc finger nucleases
MH Porteus et al.
NATURE BIOTECHNOLOGY (2005)
Distinguishing modes of cell death using the ImageStream® multispectral imaging flow cytometer
TC George et al.
CYTOMETRY PART A (2004)
Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break
R Shroff et al.
CURRENT BIOLOGY (2004)
Share Paper
