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Paracrine Hedgehog Signaling in Stomach and Intestine: New Roles for Hedgehog in Gastrointestinal Patterning
Asa Kolterud et al.
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G. Kallifatidis et al.
GUT (2009)
Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine
Silvia Fre et al.
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Hedgehog: functions and mechanisms
Markku Varjosalo et al.
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Prostate cancer stem cells: A new target for therapy
Norman J. Maitland et al.
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Bruce M. Boman et al.
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Cancer stem cells: A step toward the cure
Bruce M. Boman et al.
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Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity
L. Vermeulen et al.
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β-catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors
Julie Pannequin et al.
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Phenotypic characterization of human colorectal cancer stem cells
Piero Dalerba et al.
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Christine Marzano et al.
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A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
Catherine A. O'Brien et al.
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SMAD4-deficient intestinal tumors recruit CCR1(+) myeloid cells that promote invasion
Takanori Kitamura et al.
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Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth
FM Corvinus et al.
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PI3K/Akt/mTOR pathway as a target for cancer therapy
D Morgensztern et al.
ANTI-CANCER DRUGS (2005)
Identification of human brain tumour initiating cells
SK Singh et al.
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Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
JK Chen et al.
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STATs: Transcriptional control and biological impact
DE Levy et al.
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Protective effects of flavonoids in the roots of Scutellaria baicalensis Georgi against hydrogen peroxide-induced oxidative stress in HS-SY5Y cells
ZH Gao et al.
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Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer
S Giacchetti et al.
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