Journal
ANTIBIOTICS-BASEL
Volume 11, Issue 1, Pages -Publisher
MDPI
DOI: 10.3390/antibiotics11010031
Keywords
antibiotics; liver cirrhosis; ascites; spontaneous bacterial peritonitis; hepatic encephalopathy
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This narrative review aims to provide physicians with basic and practical knowledge for efficiently choosing the best antibiotic therapy in patients with liver cirrhosis and ongoing infections.
The liver is the primary site of drug metabolism, which can be altered by a variety of diseases affecting the liver parenchyma, especially in patients with liver cirrhosis. The use of antibiotics in patients with cirrhosis is usually a matter of concern for physicians, given the lack of practical knowledge for drug choice and eventual dose adjustments in several clinical scenarios. The aim of the current narrative review is to report, as broadly as possible, basic, and practical knowledge that any physician should have when approaching a patient with liver cirrhosis and an ongoing infection to efficiently choose the best antibiotic therapy.
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