4.6 Article

Unilateral Corneal Insult Also Alters Sensory Nerve Activity in the Contralateral Eye

Related references

Note: Only part of the references are listed.
Article Ophthalmology

Modulating Ocular Surface Pain Through Neurokinin-1 Receptor Blockade

Romina Mayra Lasagni Vitar et al.

Summary: This study demonstrates that the NK1R antagonist fosaprepitant effectively reduces ocular surface nociception by decreasing SP release and leukocyte infiltration. Fosaprepitant repurposing shows promise for the treatment of ocular pain.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2021)

Review Cell Biology

Corneal neuromediator profiles following laser refractive surgery

Lily Wei Yun Yang et al.

Summary: Laser refractive surgery can lead to changes in neuromediator profiles and ocular surface parameters, influenced by surgical techniques and the severity of tissue insult. Neuromediators play significant roles in corneal nerve regeneration and neurogenic inflammation.

NEURAL REGENERATION RESEARCH (2021)

Article Ophthalmology

Sodium Channel Blockers Modulate Abnormal Activity of Regenerating Nociceptive Corneal Nerves After Surgical Lesion

Carolina Luna et al.

Summary: The study tested the effect of different sodium channel blockers on the electrical activity of corneal nociceptors in intact and surgically injured corneas, and found that these drugs can decrease the excitability of corneal nociceptor fibers, thus mitigating their abnormal activity.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2021)

Article Multidisciplinary Sciences

Time course of bilateral microglial activation in a mouse model of laser-induced glaucoma

Ana Ramirez et al.

SCIENTIFIC REPORTS (2020)

Article Neurosciences

Piezo2 Mediates Low-Threshold Mechanically Evoked Pain in the Cornea

Jorge Fernandez-Trillo et al.

JOURNAL OF NEUROSCIENCE (2020)

Article Ophthalmology

Functional Properties of Sensory Nerve Terminals of the Mouse Cornea

Omar Gonzalez-Gonzalez et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2017)

Article Multidisciplinary Sciences

TRPM8 is a neuronal osmosensor that regulates eye blinking in mice

Talisia Quallo et al.

NATURE COMMUNICATIONS (2015)

Article Ophthalmology

Molecular Inflammation in the Contralateral Eye After Cataract Surgery in the First Eye

Xiang-Jia Zhu et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2015)

Article Neurosciences

Piezo2 Expression in Corneal Afferent Neurons

Romke Bron et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2014)

Article Ophthalmology

Ocular Surface Injury Induces Inflammation in the Brain: In Vivo and Ex Vivo Evidence of a Corneal-Trigeminal Axis

Giulio Ferrari et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2014)

Article Ophthalmology

Corneal Sensory Nerve Activity in an Experimental Model of UV Keratitis

M. Carmen Acosta et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2014)

Review Ophthalmology

The role of corneal afferent neurons in regulating tears under normal and dry eye conditions

Ian D. Meng et al.

EXPERIMENTAL EYE RESEARCH (2013)

Article Cell Biology

Direct inhibition of the cold-activated TRPM8 ion channel by Gαq

Xuming Zhang et al.

NATURE CELL BIOLOGY (2012)

Article Ophthalmology

Inflammation and the Nervous System: The Connection in the Cornea in Patients with Infectious Keratitis

Andrea Cruzat et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)

Article Biochemistry & Molecular Biology

Ocular surface wetness is regulated by TRPM8-dependent cold thermoreceptors of the cornea

Andres Parra et al.

NATURE MEDICINE (2010)

Article Ophthalmology

Selective Changes in Human Corneal Sensation Associated with Herpes Simplex Virus Keratitis

Juana Gallar et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2010)

Review Neurosciences

Molecular and cellular limits to somatosensory specificity

Carlos Belmonte et al.

MOLECULAR PAIN (2008)

Article Ophthalmology

Impulse activity in corneal sensory nerve fibers after photorefractive keratectomy

Juana Gallar et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2007)

Article Ophthalmology

Tear secretion induced by selective stimulation of corneal and conjunctival sensory nerve fibers

MC Acosta et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2004)

Review Ophthalmology

Corneal nerves:: structure, contents and function

LJ Müller et al.

EXPERIMENTAL EYE RESEARCH (2003)