Journal
FRONTIERS IN MEDICINE
Volume 8, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fmed.2021.798095
Keywords
mRNA vaccine; T cell; lymphoma; COVID-19; angioimmunoblastic; follicular
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Funding
- Fonds Erasme
- Association Vincotte Nuclear (Belgium)
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Nucleoside-modified mRNA vaccines have a strong impact on T follicular helper cells, which may influence the development of neoplasms. This report discusses the unexpected rapid progression of lymphomatous lesions in a man diagnosed with AITL after receiving a BNT162b2 mRNA vaccine booster.
Since nucleoside-modified mRNA vaccines strongly activate T follicular helper cells, it is important to explore the possible impact of approved SARS-CoV-2 mRNA vaccines on neoplasms affecting this cell type. Herein, we report and discuss unexpected rapid progression of lymphomatous lesions after administration of a BNT162b2 mRNA vaccine booster in a man recently diagnosed with AITL.
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