4.6 Article

LRMP Associates With Immune Infiltrates and Acts as a Prognostic Biomarker in Lung Adenocarcinoma

Related references

Note: Only part of the references are listed.
Review Oncology

Siglec-15 as an Emerging Target for Next-generation Cancer Immunotherapy

Jingwei Sun et al.

Summary: Immunomodulatory agents targeting the PD-1/PD-L1 pathway have shown success in cancer treatment, but resistance remains a challenge. The identification of Siglec-15 as a potential immune suppressor offers a new avenue for immunotherapy, particularly in patients resistant to anti-PD-1/PD-L1 therapy.

CLINICAL CANCER RESEARCH (2021)

Article Oncology

Identification of prognostic biomarkers associated with metastasis and immune infiltration in osteosarcoma

Bingsheng Yang et al.

Summary: This study investigated the association between tumor microenvironment and osteosarcoma metastasis, using bioinformatics analysis to identify genes associated with metastasis and immune infiltration. The research proposed a five-biomarker prognostic signature that showed high predictive accuracy for the prognosis of osteosarcoma, with potential prognostic biomarkers that were positively associated with immune-related processes and various immune cells.

ONCOLOGY LETTERS (2021)

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Biochemistry & Molecular Biology

LY6K-AS lncRNA is a lung adenocarcinoma prognostic biomarker and regulator of mitotic progression

Mohamad Moustafa Ali et al.

Summary: Recent research has identified the antisense transcript LY6K-AS as a potential therapeutic target for lung adenocarcinoma. Its silencing can inhibit the oncogenic mitotic progression of lung cancer cells.

ONCOGENE (2021)

Article Biochemistry & Molecular Biology

TISCH: a comprehensive web resource enabling interactive single-cell transcriptome visualization of tumor microenvironment

Dongqing Sun et al.

Summary: Cancer immunotherapy targeting co-inhibitory pathways by checkpoint blockade has shown significant efficacy, but only a minority of patients respond due to tumor microenvironment heterogeneity. TISCH is a large curated database that integrates single-cell transcriptomic profiles from 76 high-quality tumor datasets across 27 cancer types, providing a user-friendly interface for exploring gene expression atlas in the TME from multiple cancer types.

NUCLEIC ACIDS RESEARCH (2021)

Review Oncology

STAT3 Activation and Oncogenesis in Lymphoma

Fen Zhu et al.

CANCERS (2020)

Article Biochemistry & Molecular Biology

TIMER2.0 for analysis of tumor-infiltrating immune cells

Taiwen Li et al.

NUCLEIC ACIDS RESEARCH (2020)

Review Biochemistry & Molecular Biology

The Role of Cell Adhesion Molecule 1 (CADM1) in Cutaneous Malignancies

Yu Sawada et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Biotechnology & Applied Microbiology

Recognition of Immune Microenvironment Landscape and Immune-Related Prognostic Genes in Breast Cancer

Huiling Wang et al.

BIOMED RESEARCH INTERNATIONAL (2020)

Article Biochemical Research Methods

TISIDB: an integrated repository portal for tumor-immune system interactions

Beibei Ru et al.

BIOINFORMATICS (2019)

Article Biochemistry & Molecular Biology

GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis

Zefang Tang et al.

NUCLEIC ACIDS RESEARCH (2019)

Review Cell Biology

KLHL6 is a tumor suppressor gene in diffuse large B-cell lymphoma

Jaewoo Choi et al.

CELL CYCLE (2019)

Review Cell Biology

Immune checkpoint inhibitors in cancer therapy: a focus on T-regulatory cells

Varun Sasidharan Nair et al.

IMMUNOLOGY AND CELL BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Jaw1/LRMP has a role in maintaining nuclear shape via interaction with SUN proteins

Takuma Kozono et al.

JOURNAL OF BIOCHEMISTRY (2018)

Review Oncology

The next generation of immunotherapy: keeping lung cancer in check

Ashwin Somasundaram et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)

Article Oncology

Diagnostic and prognostic value of serum interleukin-16 in patients with gastric cancer

Hongyun Yang et al.

MOLECULAR MEDICINE REPORTS (2017)

Article Biochemistry & Molecular Biology

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

Zefang Tang et al.

NUCLEIC ACIDS RESEARCH (2017)

Article Oncology

Gene expression markers of Tumor Infiltrating Leukocytes

Patrick Danaher et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2017)

Review Immunology

Mechanisms and consequences of Jak-STAT signaling in the immune system

Alejandro V. Villarino et al.

NATURE IMMUNOLOGY (2017)

Article Immunology

Identification of CD112R as a novel checkpoint for human T cells

Yuwen Zhu et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2016)

Article Multidisciplinary Sciences

Actin nucleation at the centrosome controls lymphocyte polarity

Dorian Obino et al.

NATURE COMMUNICATIONS (2016)

Article Oncology

The role of tumour-associated macrophages in bone metastasis

Sofia Sousa et al.

JOURNAL OF BONE ONCOLOGY (2016)

Article Biotechnology & Applied Microbiology

Comprehensive analyses of tumor immunity: implications for cancer immunotherapy

Bo Li et al.

GENOME BIOLOGY (2016)

Article Medicine, General & Internal

Pembrolizumab for the Treatment of Non-Small-Cell Lung Cancer

Edward B. Garon et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Medicine, General & Internal

Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung Cancer

H. Borghaei et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Medicine, General & Internal

Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma

R. J. Motzer et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Medicine, General & Internal

Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma

J. Larkin et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article

Review The Cancer Genome Atlas (TCGA): an immeasurable source of knowledge

Katarzyna Tomczak et al.

Wspolczesna Onkologia-Contemporary Oncology (2015)

Article Multidisciplinary Sciences

Systematic pan-cancer analysis of tumour purity

Dvir Aran et al.

NATURE COMMUNICATIONS (2015)