4.6 Article

Structural and Functional Insights into the Microtubule Organizing Centers of Toxoplasma gondii and Plasmodium spp.

Related references

Note: Only part of the references are listed.
Article Biology

Protein phosphatase 1 regulates atypical mitotic and meiotic division in Plasmodium sexual stages

Mohammad Zeeshan et al.

Summary: Using various techniques, Zeeshan et al. found that Plasmodium PP1 plays a role in mitotic exit and potentially establishing cell polarity during zygote development in the mosquito midgut, suggesting that targeting PP1 with small molecule inhibitors could be a promising approach to block parasite transmission.

COMMUNICATIONS BIOLOGY (2021)

Review Parasitology

The Multifaceted Role of Protein Phosphatase 1 in Plasmodium

Jamal Khalife et al.

Summary: Protein phosphatase type 1 (PP1) is a key enzyme present in all eukaryotic cells, forming holoenzymes with regulatory proteins to control cellular functions. Recent studies have focused on the role of PP1 in Plasmodium, its interactome, and potential as drug targets. Peptides disrupting PP1's interaction with regulatory proteins show promise as inhibitors of Plasmodium growth.

TRENDS IN PARASITOLOGY (2021)

Article Biochemistry & Molecular Biology

Expansion microscopy provides new insights into the cytoskeleton of malaria parasites including the conservation of a conoid

Eloise Bertiaux et al.

Summary: The study demonstrates that ultrastructure expansion microscopy (U-ExM) can reveal detailed organization of nanoscale cytoskeleton in Plasmodium parasites, and shows that a divergent and considerably reduced form of the conoid is actually conserved in Plasmodium species.

PLOS BIOLOGY (2021)

Editorial Material Biochemistry & Molecular Biology

Apicomplexans: A conoid ring unites them all

Julien Guizetti et al.

Summary: The discovery of a conserved ring structure in apicomplexan parasites challenges the long-standing paradigm, indicating a crucial element present throughout the entire phylum.

PLOS BIOLOGY (2021)

Article Microbiology

Revisiting the Role of Toxoplasma gondii ERK7 in the Maintenance and Stability of the Apical Complex

Nicolas Dos Santos Pacheco et al.

Summary: Depletion of ERK7 in Toxoplasma gondii disrupts the integrity of the apical complex, leading to the loss of the apical polar ring and impairment in microneme secretion. Comparative proteomics analysis reveals the disappearance of known apical complex proteins and the accumulation of microneme proteins.
Review Immunology

The Modular Circuitry of Apicomplexan Cell Division Plasticity

Marc-Jan Gubbels et al.

Summary: The close-knit group of apicomplexan parasites demonstrate a variety of cell division modes, showing plasticity due to a combination of environmental triggers and hard-wired developmental programs. The division modes and cell cycle progression are influenced by environmental and genetic inputs, resulting in a variety of outcomes.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)

Article Multidisciplinary Sciences

Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes

Aditya S. Paul et al.

NATURE COMMUNICATIONS (2020)

Review Parasitology

The Riveting Cellular Structures of Apicomplexan Parasites

Clare R. Harding et al.

TRENDS IN PARASITOLOGY (2020)

Review Immunology

The Structural and Molecular Underpinnings of Gametogenesis in Toxoplasma gondii

Ramiro Tomasina et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2020)

Article Multidisciplinary Sciences

An experimental genetically attenuated live vaccine to prevent transmission of Toxoplasma gondii by cats

Chandra Ramakrishnan et al.

SCIENTIFIC REPORTS (2019)

Article Multidisciplinary Sciences

Plasmodium pseudo-Tyrosine Kinase-like binds PP1 and SERA5 and is exported to host erythrocytes

Benedicte Gnangnon et al.

SCIENTIFIC REPORTS (2019)

Article Biochemistry & Molecular Biology

Intestinal delta-6-desaturase activity determines host range for Toxoplasma sexual reproduction

Bruno Martorelli Di Genova et al.

PLOS BIOLOGY (2019)

Review Parasitology

Checks and balances? DNA replication and the cell cycle in Plasmodium

Holly Matthews et al.

PARASITES & VECTORS (2018)

Review Biochemistry & Molecular Biology

The serine/threonine phosphatases of apicomplexan parasites

Chunlin Yang et al.

MOLECULAR MICROBIOLOGY (2017)

Article Microbiology

The Toxoplasma Centrocone Houses Cell Cycle Regulatory Factors

Anatoli Naumov et al.

Article Microbiology

Checkpoints of apicomplexan cell division identified in Toxoplasma gondii

Carmelo A. Alvarez et al.

PLOS PATHOGENS (2017)

Review Cell Biology

Towards a molecular architecture of the centrosome in Toxoplasma gondii

Juliette Morlon-Guyot et al.

CYTOSKELETON (2017)

Article Cell Biology

Microtubule-organizing centers: from the centrosome to non-centrosomal sites

Ariana D. Sanchez et al.

CURRENT OPINION IN CELL BIOLOGY (2017)

Article Biochemistry & Molecular Biology

CDK1 Prevents Unscheduled PLK4-STIL Complex Assembly in Centriole Biogenesis

Sihem Zitouni et al.

CURRENT BIOLOGY (2016)

Review Genetics & Heredity

Regulation of DNA replication proteins in parasitic protozoans: possible role of CDK-like kinases

Abhijit S. Deshmukh et al.

CURRENT GENETICS (2016)

Editorial Material Cell Biology

The Secret of Centriole Length: Keep a LID on It

Kevin C. Slep

DEVELOPMENTAL CELL (2016)

Article Biochemistry & Molecular Biology

A Novel Bipartite Centrosome Coordinates the Apicomplexan Cell Cycle

Elena S. Suvorova et al.

PLOS BIOLOGY (2015)

Review Microbiology

Cell division in apicomplexan parasites

Maria E. Francia et al.

NATURE REVIEWS MICROBIOLOGY (2014)

Review Biology

Historical roots of centrosome research: discovery of Boveri's microscope slides in Wurzburg

Ulrich Scheer

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Review Biology

Pericentriolar material structure and dynamics

Jeffrey B. Woodruff et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)

Review Biochemistry & Molecular Biology

Nima- and Aurora-related kinases of malaria parasites

Teresa Gil Carvalho et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2013)

Editorial Material Biochemistry & Molecular Biology

Spindle pole bodies

Christian Seybold et al.

CURRENT BIOLOGY (2013)

Article Biochemistry & Molecular Biology

Human microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assembly

Yu-Chih Lin et al.

EMBO JOURNAL (2013)

Review Biochemistry & Molecular Biology

The PP1 binding code: a molecular-lego strategy that governs specificity

Ewald Heroes et al.

FEBS JOURNAL (2013)

Article Cell Biology

The where, when and how of microtubule nucleation - one ring to rule them all

Neus Teixido-Travesa et al.

JOURNAL OF CELL SCIENCE (2012)

Article Biochemistry & Molecular Biology

Structural Basis of the 9-Fold Symmetry of Centrioles

Daiju Kitagawa et al.

Review Microbiology

Mitosis in the Human Malaria Parasite Plasmodium falciparum

Noel Gerald et al.

EUKARYOTIC CELL (2011)

Article Multidisciplinary Sciences

Toxoplasma gondii sequesters centromeres to a specific nuclear region throughout the cell cycle

Carrie F. Brooks et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falciparum

Lev Solyakov et al.

NATURE COMMUNICATIONS (2011)

Article Cell Biology

Positioning of large organelles by a membrane- associated cytoskeleton in Plasmodium sporozoites

Mikhail Kudryashev et al.

CELLULAR MICROBIOLOGY (2010)

Review Biochemistry & Molecular Biology

Plus-End-Tracking Proteins and Their Review Interactions at Microtubule Ends

Niels Galjart

CURRENT BIOLOGY (2010)

Article Cell Biology

RNG1 is a Late Marker of the Apical Polar Ring in Toxoplasma gondii

Johnson Q. Tran et al.

CYTOSKELETON (2010)

Article Biochemistry & Molecular Biology

Self-assembling SAS-6 Multimer Is a Core Centriole Building Block

Jayachandran Gopalakrishnan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Cell Biology

Reconstructing the evolutionary history of the centriole from protein components

Matthew E. Hodges et al.

JOURNAL OF CELL SCIENCE (2010)

Article Cell Biology

Stepwise evolution of the centriole-assembly pathway

Zita Carvalho-Santos et al.

JOURNAL OF CELL SCIENCE (2010)

Article Multidisciplinary Sciences

Microtubule nucleating γ-TuSC assembles structures with 13-fold microtubule-like symmetry

Justin M. Kollman et al.

NATURE (2010)

Review Biochemistry & Molecular Biology

Evolution of protein phosphatases in plants and animals

Greg B. G. Moorhead et al.

BIOCHEMICAL JOURNAL (2009)

Article Biochemistry & Molecular Biology

An Essential Role for the Plasmodium Nek-2 Nima-related Protein Kinase in the Sexual Development of Malaria Parasites

Luc Reininger et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Cell Biology

The Two SAS-6 Homologs in Tetrahymena thermophila Have Distinct Functions in Basal Body Assembly

Brady P. Culver et al.

MOLECULAR BIOLOGY OF THE CELL (2009)

Review Microbiology

Building the perfect parasite: Cell division in Apicomplexa

Boris Striepen et al.

PLOS PATHOGENS (2007)

Article Multidisciplinary Sciences

Centriole assembly in Caenorhabditis elegans

Laurence Pelletier et al.

NATURE (2006)

Article Cell Biology

A MORN-repeat protein is a dynamic component of the Toxoplasma gondii cell division apparatus

Marc-Jan Gubbels et al.

JOURNAL OF CELL SCIENCE (2006)

Article Biochemistry & Molecular Biology

SAK/PLK4 is required for centriole duplication and flagella development

M Bettencourt-Dias et al.

CURRENT BIOLOGY (2005)

Article Cell Biology

Centriole assembly requires both centriolar and pericentriolar material proteins

A Dammermann et al.

DEVELOPMENTAL CELL (2004)

Article Multidisciplinary Sciences

Proteomic characterization of the human centrosome by protein correlation profiling

JS Andersen et al.

NATURE (2003)

Article Biochemistry & Molecular Biology

Inhibitor-2 regulates protein phosphatase-1 complexed with NimA-related kinase to induce centrosome separation

M Eto et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Cyclin-dependent kinase TPK2 is a critical cell cycle regulator in Toxoplasma gondii

F Khan et al.

MOLECULAR MICROBIOLOGY (2002)

Article Parasitology

Plasmodium falciparum protein phosphatase type 1 functionally complements a glc7 mutant in Saccharomyces cerevisiae

MK Bhattacharyya et al.

INTERNATIONAL JOURNAL FOR PARASITOLOGY (2002)

Article Biochemistry & Molecular Biology

Microtubule associated motor proteins of Plasmodium falciparum merozoites

RE Fowler et al.

MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2001)

Article Cell Biology

The plastid of Toxoplasma gondii is divided by association with the centrosomes

B Striepen et al.

JOURNAL OF CELL BIOLOGY (2000)