4.7 Review

An Overview of Physical Exercise and Antioxidant Supplementation Influences on Skeletal Muscle Oxidative Stress

Journal

ANTIOXIDANTS
Volume 10, Issue 10, Pages -

Publisher

MDPI
DOI: 10.3390/antiox10101528

Keywords

reactive oxygen species; oxidative stress; skeletal muscle; physical activity; antioxidant supplementation

Funding

  1. Ministry of Education, Culture, Sports, Science, and Technology of Japan [20H00574]
  2. Grants-in-Aid for Scientific Research [20H00574] Funding Source: KAKEN

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Moderate to high-intensity and short-duration physical activities can lead to overproduction of reactive oxygen species (ROS), causing damage to body tissues, while antioxidant defense systems can control ROS effectively during low to moderate intensity and long-term exercises. In stressful situations, antioxidant supplements can be considered to prevent ROS damage. Further research needs to take into account factors such as dosage and duration of antioxidant supplements, exercise intensity, duration, frequency, among others.
One of the essential injuries caused by moderate to high-intensity and short-duration physical activities is the overproduction of reactive oxygen species (ROS), damaging various body tissues such as skeletal muscle (SM). However, ROS is easily controlled by antioxidant defense systems during low to moderate intensity and long-term exercises. In stressful situations, antioxidant supplements are recommended to prevent ROS damage. We examined the response of SM to ROS generation during exercise using an antioxidant supplement treatment strategy in this study. The findings of this review research are paradoxical due to variances in antioxidant supplements dose and duration, intensity, length, frequency, types of exercise activities, and, in general, the lack of a regular exercise and nutrition strategy. As such, further research in this area is still being felt.

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