Related references
Note: Only part of the references are listed.Urokinase plasminogen activator as an anti-metastasis target: inhibitor design principles, recent amiloride derivatives, and issues with human/mouse species selectivity
Nehad S. El Salamouni et al.
BIOPHYSICAL REVIEWS (2022)
Plasma suPAR may help to distinguish between chronic pancreatitis and pancreatic cancer
Anu Aronen et al.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY (2021)
Tumor-Associated Macrophages in Pancreatic Ductal Adenocarcinoma: Origin, Polarization, Function, and Reprogramming
Sen Yang et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Hyuna Sung et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2021)
The CDCP1 Signaling Hub: A Target for Cancer Detection and Therapeutic Intervention
Tashbib Khan et al.
CANCER RESEARCH (2021)
Prognostic values and immune suppression of the S100A family in pancreatic cancer
Hongkai Zhuang et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)
Alpha-Enolase: Emerging Tumor-Associated Antigen, Cancer Biomarker, and Oncotherapeutic Target
Frankis A. Almaguel et al.
FRONTIERS IN GENETICS (2021)
The State-of-the-Art of Phase II/III Clinical Trials for Targeted Pancreatic Cancer Therapies
Andres Garcia-Sampedro et al.
JOURNAL OF CLINICAL MEDICINE (2021)
Enolase 1 Correlated With Cancer Progression and Immune-Infiltrating in Multiple Cancer Types: A Pan-Cancer Analysis
Wenhua Xu et al.
FRONTIERS IN ONCOLOGY (2021)
Systematic evaluation of structure?property relationships and pharmacokinetics in 6-(hetero)aryl-substituted matched pair analogs of amiloride and 5-(N,N-hexamethylene)amiloride
Benjamin J. Buckley et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2021)
Screening of 5-and 6-Substituted Amiloride Libraries Identifies Dual-uPA/NHE1 Active and Single Target-Selective Inhibitors
Benjamin J. Buckley et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Substrate-biased activity-based probes identify proteases that cleave receptor CDCP1
Thomas Kryza et al.
NATURE CHEMICAL BIOLOGY (2021)
Comprehensive analysis of the transcriptional expressions and prognostic value of S100A family in pancreatic ductal adenocarcinoma
Hong-Bin Li et al.
BMC CANCER (2021)
CA19-9 for detecting recurrence of pancreatic cancer
Azadeh Azizian et al.
SCIENTIFIC REPORTS (2020)
Theranostic Targeting of CUB Domain Containing Protein 1 (CDCP1) in Pancreatic Cancer
Anna Moroz et al.
CLINICAL CANCER RESEARCH (2020)
Carbohydrate antigen 19-9 elevation without evidence of malignant or pancreatobiliary diseases
Sunyoung Kim et al.
SCIENTIFIC REPORTS (2020)
Biomarker Panel for the Diagnosis of Pancreatic Ductal Adenocarcinoma
Hongbeom Kim et al.
CANCERS (2020)
Tumor Microenvironment: Extracellular Matrix Alterations Influence Tumor Progression
Sylvie Brassart-Pasco et al.
FRONTIERS IN ONCOLOGY (2020)
Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer
Yingsong Lin et al.
NATURE COMMUNICATIONS (2020)
A comprehensive analysis of clinical trials in pancreatic cancer: what is coming down the pike?
Erryk S. Katayama et al.
Oncotarget (2020)
The actual 5-year survivors of pancreatic ductal adenocarcinoma based on real-world data
Axel Bengtsson et al.
SCIENTIFIC REPORTS (2020)
The Diagnostic Accuracy of Combined Enolase/Cr, CA125, and CA19-9 in the Detection of Endometriosis
Samaneh Rokhgireh et al.
BIOMED RESEARCH INTERNATIONAL (2020)
Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma
Thomas Kryza et al.
THERANOSTICS (2020)
High baseline soluble urokinase plasminogen activator receptor (suPAR) serum levels indicate adverse outcome after resection of pancreatic adenocarcinoma
Sven H. Loosen et al.
CARCINOGENESIS (2019)
Diagnosis and Management of Pancreatic Adenocarcinoma in the Background of Chronic Pancreatitis: Core Issues
Narkhede A. Rajvilas et al.
DIGESTIVE DISEASES (2019)
Early Detection of Pancreatic Cancer: Opportunities and Challenges
Aatur D. Singhi et al.
GASTROENTEROLOGY (2019)
Cell surface-anchored serine proteases in cancer progression and metastasis
Carly E. Martin et al.
CANCER AND METASTASIS REVIEWS (2019)
Pancreatic ductal adenocarcinoma: biological hallmarks, current status, and future perspectives of combined modality treatment approaches
Michael Orth et al.
RADIATION ONCOLOGY (2019)
The plasminogen activator inhibitor-1 paradox in cancer: a mechanistic understanding
Marta Helena Kubala et al.
CANCER AND METASTASIS REVIEWS (2019)
6-Substituted amiloride derivatives as inhibitors of the urokinase-type plasminogen activator for use in metastatic disease
Benjamin J. Buckley et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2019)
Tumor-associated macrophages: an accomplice in solid tumor progression
Yibing Chen et al.
JOURNAL OF BIOMEDICAL SCIENCE (2019)
Epidemiology of Pancreatic Cancer: Global Trends, Etiology and Risk Factors
Prashanth Rawla et al.
WORLD JOURNAL OF ONCOLOGY (2019)
Annexin A2 and cancer: A systematic review
Maria V. Christensen et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2018)
CA19-9 on Postoperative Surveillance in Pancreatic Ductal Adenocarcinoma: Predicting Recurrence and Changing Prognosis over Time
Caroline J. Rieser et al.
ANNALS OF SURGICAL ONCOLOGY (2018)
Diversity and functional evolution of the plasminogen activator system
Rishi Kumar Jaiswal et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
S100A10, a novel biomarker in pancreatic ductal adenocarcinoma
Moamen Bydoun et al.
MOLECULAR ONCOLOGY (2018)
Therapeutic developments in pancreatic cancer: current and future perspectives
John P. Neoptolemos et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2018)
Advances in Diagnostic and Intraoperative Molecular Imaging of Pancreatic Cancer
Willemieke S. Tummers et al.
PANCREAS (2018)
ENO1 Overexpression in Pancreatic Cancer Patients and Its Clinical and Diagnostic Significance
Hang Yin et al.
GASTROENTEROLOGY RESEARCH AND PRACTICE (2018)
Clinical significance of pancreatic intraepithelial neoplasia in resectable pancreatic cancer on survivals
Da-Young Yu et al.
ANNALS OF SURGICAL TREATMENT AND RESEARCH (2018)
Stratified survival of resected and overall pancreatic cancer patients in Europe and the USA in the early twenty-first century: a large, international population-based study
Lei Huang et al.
BMC MEDICINE (2018)
6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer
Benjamin J. Buckley et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Plasminogen Activator Inhibitor 1 as a Poor Prognostic Indicator in Resectable Pancreatic Ductal Adenocarcinoma
Wen-Jing Liu et al.
CHINESE MEDICAL JOURNAL (2018)
Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes
Andrew McGuigan et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2018)
International Validation of the Eighth Edition of the American Joint Committee on Cancer (AJCC) TNM Staging System in Patients With Resected Pancreatic Cancer
Stijn van Roessel et al.
JAMA SURGERY (2018)
Enolase-1 serves as a biomarker of diagnosis and prognosis in hepatocellular carcinoma patients
Weiwei Zhu et al.
CANCER MANAGEMENT AND RESEARCH (2018)
Tumor-Stroma Cross-Talk in Human Pancreatic Ductal Adenocarcinoma: A Focus on the Effect of the Extracellular Matrix on Tumor Cell Phenotype and Invasive Potential
Patrizia Procacci et al.
CELLS (2018)
Safety, Dosimetry, and Tumor Detection Ability of 68Ga-NOTA-AE105: First-in-Human Study of a Novel Radioligand for uPAR PET Imaging
Dorthe Skovgaard et al.
JOURNAL OF NUCLEAR MEDICINE (2017)
Over-Expression of Alpha-Enolase as a Prognostic Biomarker in Patients with Pancreatic Cancer
Lichao Sun et al.
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2017)
Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis
Moitza Principe et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)
SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer
N. L. E. Harris et al.
ONCOGENE (2017)
Stromal Annexin A2 expression is predictive of decreased survival in pancreatic cancer
Adrian G. Murphy et al.
ONCOTARGET (2017)
The urokinase plasminogen activation system in gastroesophageal cancer: A systematic review and meta-analysis
Daniel Brungs et al.
ONCOTARGET (2017)
Pancreatic Cancer Chemoresistance to Gemcitabine
Manoj Amrutkar et al.
CANCERS (2017)
Near-infrared fluorophores for biomedical imaging
Guosong Hong et al.
NATURE BIOMEDICAL ENGINEERING (2017)
Randomized phase II trial with an uPA inhibitor (WX-671) in patients with locally advanced nonmetastatic pancreatic cancer.
V. Heinemann et al.
JOURNAL OF CLINICAL ONCOLOGY (2017)
Prognostic Impact of Urokinase Plasminogen Activator Receptor Expression in Pancreatic Cancer: Malignant Versus Stromal Cells
Susanna W. L. de Geus et al.
BIOMARKER INSIGHTS (2017)
Cleavage of the urokinase receptor (uPAR) on oral cancer cells: regulation by transforming growth factor - β1 (TGF-β1) and potential effects on migration and invasion
Synnove Norvoll Magnussen et al.
BMC CANCER (2017)
Employing Metabolism to Improve the Diagnosis and Treatment of Pancreatic Cancer
Christopher J. Habrook et al.
CANCER CELL (2017)
A multicentre comparative prospective blinded analysis of EUS and MRI for screening of pancreatic cancer in high-risk individuals
F. Harinck et al.
GUT (2016)
Targeting the Warburg effect in cancer cells through ENO1 knockdown rescues oxidative phosphorylation and induces growth arrest
Michela Capello et al.
ONCOTARGET (2016)
Antibody-based PET of uPA/uPAR signaling with broad applicability for cancer imaging
Dongzhi Yang et al.
ONCOTARGET (2016)
Targeting of surface alpha-enolase inhibits the invasiveness of pancreatic cancer cells
Moitza Principe et al.
ONCOTARGET (2015)
Molecular landscape of pancreatic cancer: implications for current clinical trials
Gregory M. Heestand et al.
ONCOTARGET (2015)
First-in-human uPAR PET: Imaging of Cancer Aggressiveness
Morten Persson et al.
THERANOSTICS (2015)
Matrix metalloproteinase-10 promotes tumor progression through regulation of angiogenic and apoptotic pathways in cervical tumors
Ge Zhang et al.
BMC CANCER (2014)
Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States
Lola Rahib et al.
CANCER RESEARCH (2014)
FOXM1c Promotes Pancreatic Cancer Epithelial-to-Mesenchymal Transition and Metastasis via Upregulation of Expression of the Urokinase Plasminogen Activator System
Chen Huang et al.
CLINICAL CANCER RESEARCH (2014)
From Plasminogen to Plasmin: Role of Plasminogen Receptors in Human Cancer
Miroslava Didiasova et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)
Prevention and early detection of prostate cancer
Jack Cuzick et al.
LANCET ONCOLOGY (2014)
Adenoma Detection Rate and Risk of Colorectal Cancer and Death
Douglas A. Corley et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Imaging diagnosis of pancreatic cancer: A state-of-the-art review
Eun Sun Lee et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2014)
Application of Molecular Modeling to Urokinase Inhibitors Development
V. B. Sulimov et al.
BIOMED RESEARCH INTERNATIONAL (2014)
uPA and PAI-1 as biomarkers in breast cancer: validated for clinical use in level-of-evidence-1 studies
Michael J. Duffy et al.
BREAST CANCER RESEARCH (2014)
Urokinase-type plasminogen activator receptor (uPAR) as a promising new imaging target: potential clinical applications
Morten Persson et al.
CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING (2013)
Vaccination With ENO1 DNA Prolongs Survival of Genetically Engineered Mice With Pancreatic Cancer
Paola Cappello et al.
GASTROENTEROLOGY (2013)
Annexin A2 Heterotetramer: Structure and Function
Alamelu Bharadwaj et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Adjuvant Chemotherapy With Gemcitabine and Long-term Outcomes Among Patients With Resected Pancreatic Cancer The CONKO-001 Randomized Trial
Helmut Oettle et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2013)
The clinical significance of S100A10 in pancreatic cancer
Naoto Yamamoto et al.
JOURNAL OF CLINICAL ONCOLOGY (2013)
First 18F-labeled ligand for PET imaging of uPAR: In vivo studies in human prostate cancer xenografts
Morten Persson et al.
NUCLEAR MEDICINE AND BIOLOGY (2013)
Understanding the Role of Keratins 8 and 18 in Neoplastic Potential of Breast Cancer Derived Cell Lines
Sapna V. Iyer et al.
PLOS ONE (2013)
Plasminogen Receptors: The First Quarter Century
Lindsey A. Miles et al.
SEMINARS IN THROMBOSIS AND HEMOSTASIS (2013)
Pancreatic cancer: why is it so hard to treat?
Paul E. Oberstein et al.
THERAPEUTIC ADVANCES IN GASTROENTEROLOGY (2013)
Three are better than one: plasminogen receptors as cancer theranostic targets
Patrizia Ceruti et al.
EXPERIMENTAL HEMATOLGY & ONCOLOGY (2013)
Survival after Resection of Pancreatic Adenocarcinoma: Results from a Single Institution over Three Decades
Jordan M. Winter et al.
ANNALS OF SURGICAL ONCOLOGY (2012)
Screening for Prostate Cancer Decreases the Risk of Developing Metastatic Disease: Findings from the European Randomized Study of Screening for Prostate Cancer (ERSPC)
Fritz H. Schroder et al.
EUROPEAN UROLOGY (2012)
Urokinase plasminogen activator receptor on invasive cancer cells: A prognostic factor in distal gastric adenocarcinoma
Warner Alpizar-Alpizar et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
α-Enolase Expressed on the Surfaces of Monocytes and Macrophages Induces Robust Synovial Inflammation in Rheumatoid Arthritis
Seyeon Bae et al.
JOURNAL OF IMMUNOLOGY (2012)
Quantitative PET of Human Urokinase-Type Plasminogen Activator Receptor with Cu-64-DOTA-AE105: Implications for Visualizing Cancer Invasion
Morten Persson et al.
JOURNAL OF NUCLEAR MEDICINE (2012)
Invasive markers identified by gene expression profiling in pancreatic cancer
A. Rogers et al.
PANCREATOLOGY (2012)
VEGF-initiated angiogenesis and the uPA/uPAR system
Johannes M. Breuss et al.
CELL ADHESION & MIGRATION (2012)
The X-ray Crystal Structure of Full-Length Human Plasminogen
Ruby H. P. Law et al.
CELL REPORTS (2012)
Early Recurrence of Pancreatic Cancer after Resection and During Adjuvant Chemotherapy
Richard Fischer et al.
SAUDI JOURNAL OF GASTROENTEROLOGY (2012)
Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
Sophia Y. Lunt et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
The role of the annexin A2 heterotetramer in vascular fibrinolysis
Patricia A. Madureira et al.
BLOOD (2011)
Elevated urinary levels of urokinase-type plasminogen activator receptor (uPAR) in pancreatic ductal adenocarcinoma identify a clinically high-risk group
Claudio Sorio et al.
BMC CANCER (2011)
α-enolase: a promising therapeutic and diagnostic tumor target
Michela Capello et al.
FEBS JOURNAL (2011)
Stromal biology and therapy in pancreatic cancer
Albrecht Neesse et al.
GUT (2011)
Circulating Autoantibodies to Phosphorylated alpha-Enolase are a Hallmark of Pancreatic Cancer
Barbara Tomaino et al.
JOURNAL OF PROTEOME RESEARCH (2011)
Suppression of the uPAR-uPA System Retards Angiogenesis, Invasion, and In Vivo Tumor Development in Pancreatic Cancer Cells
Bharathi Gorantla et al.
MOLECULAR CANCER RESEARCH (2011)
Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening
Denise R. Aberle et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Tyrosine 23 Phosphorylation-Dependent Cell-Surface Localization of Annexin A2 Is Required for Invasion and Metastases of Pancreatic Cancer
Lei Zheng et al.
PLOS ONE (2011)
Swedish Two-County Trial: Impact of Mammographic Screening on Breast Cancer Mortality during 3 Decades
Laszlo Tabar et al.
RADIOLOGY (2011)
Targeted Alpha Therapy Approach to the Management of Pancreatic Cancer
Barry J. Allen et al.
Cancers (2011)
The Role of Annexin A2 in Tumorigenesis and Cancer Progression
Noor A. Lokman et al.
CANCER MICROENVIRONMENT (2011)
Proteomics-based discovery of a novel, structurally unique, and developmentally regulated plasminogen receptor, Plg-RKT, a major regulator of cell surface plasminogen activation
Nicholas M. Andronicos et al.
BLOOD (2010)
S100A10 regulates plasminogen-dependent macrophage invasion
Paul A. O'Connell et al.
BLOOD (2010)
CUB Domain-Containing Protein 1, a Prognostic Factor for Human Pancreatic Cancers, Promotes Cell Migration and Extracellular Matrix Degradation
Yuri Miyazawa et al.
CANCER RESEARCH (2010)
Challenges of drug resistance in the management of pancreatic cancer
Rizwan Sheikh et al.
EXPERT REVIEW OF ANTICANCER THERAPY (2010)
ERK and cell death: Mechanisms of ERK-induced cell death - apoptosis, autophagy and senescence
Sebastien Cagnol et al.
FEBS JOURNAL (2010)
Tumour Budding, uPA and PAI-1 Are Associated With Aggressive Behaviour in Colon Cancer
B. Maerkl et al.
JOURNAL OF SURGICAL ONCOLOGY (2010)
Regulation of cell signalling by uPAR
Harvey W. Smith et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Amplification of the Urokinase-Type Plasminogen Activator Receptor (uPAR) Gene in Ductal Pancreatic Carcinomas Identifies a Clinically High-Risk Group
Ralf Hildenbrand et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility
T. Nedjadi et al.
BRITISH JOURNAL OF CANCER (2009)
Cytokeratins 18 and 8 are poor prognostic markers in patients with squamous cell carcinoma of the oesophagus
T. Makino et al.
BRITISH JOURNAL OF CANCER (2009)
Inhibition of the p38 Kinase Suppresses the Proliferation of Human ER-Negative Breast Cancer Cells
Lu Chen et al.
CANCER RESEARCH (2009)
Challenges for Drug Discovery - A Case Study of Urokinase Receptor Inhibition
Zhuo Chen et al.
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2009)
An integrated humoral and cellular response is elicited in pancreatic cancer by α-enolase, a novel pancreatic ductal adenocarcinoma-associated antigen
Paola Cappello et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
Analysis of the Pancreatic Tumor Progression by a Quantitative Proteomic Approach and Immunhistochemical Validation
Barbara Sitek et al.
JOURNAL OF PROTEOME RESEARCH (2009)
Pancreatic cancer: molecular pathogenesis and new therapeutic targets
Han H. Wong et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2009)
Invasive front of colorectal cancer: Dynamic interface of pro-/anti-tumor factors
Inti Zlobec et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2009)
Annexin II Overexpression Predicts Rapid Recurrence after Surgery in Pancreatic Cancer Patients Undergoing Gemcitabine-Adjuvant Chemotherapy
Shigetsugu Takano et al.
ANNALS OF SURGICAL ONCOLOGY (2008)
Tumor marker utility and prognostic relevance of cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 in colorectal cancer
Laszlo Herszenyi et al.
BMC CANCER (2008)
Structure and ligand interactions of the urokinase receptor (uPAR)
Magnus Kjaergaard et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2008)
Annexin II/Annexin II receptor axis regulates adhesion, migration, homing, and growth of prostate cancer
Yusuke Shiozawa et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2008)
Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes
Qing Huai et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Prognostic significance of growth factors and the urokinase-type plasminogen activator system in pancreatic ductal adenocarcinoma
Aiqun Xue et al.
PANCREAS (2008)
Full-length cytokeratin 8 is released and circulates in patients with non-small cell lung cancer
Tomoya Ishii et al.
TUMOR BIOLOGY (2008)
Molecular characterisation of breast cancer patients at high and low recurrence risk
Serena Bonin et al.
VIRCHOWS ARCHIV (2008)
Revisiting the biological roles of PAI2 (SERPINB2) in cancer
David R. Croucher et al.
NATURE REVIEWS CANCER (2008)
A structural basis for differential cell signalling by PAI-1 and PAI-2 in breast cancer cells
David R. Croucher et al.
BIOCHEMICAL JOURNAL (2007)
Histone H2B as a functionally important plasminogen receptor on macrophages
Riku Das et al.
BLOOD (2007)
uPAR-induced cell adhesion and migration: vitronectin provides the key
Chris D. Madsen et al.
JOURNAL OF CELL BIOLOGY (2007)
Interaction between cancer cells and stromnal fibroblasts is required for activation of the uPAR-uPA-NMP-2 cascade in pancreatic cancer metastasis
Yu He et al.
CLINICAL CANCER RESEARCH (2007)
Mapping of the vitronectin-binding site on the urokinase receptor -: Involvement of a coherent receptor interface consisting of residues from both domain I and the flanking interdomain linker region
Henrik Gardsvoll et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Accurate discrimination of pancreatic ductal adenocarcinoma and chronic pancreatitis using multimarker expression data and samples obtained by minimally invasive tine needle aspiration
Yian Chen et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
High expression of plasminogen activator inhibitor-2 (PAI-2) is a predictor of improved survival in patients with pancreatic adenocarcinoma
Ross Smith et al.
WORLD JOURNAL OF SURGERY (2007)
The role of annexin II in angiogenesis and tumor progression: A potential therapeutic target
Mahesh C. Sharma et al.
CURRENT PHARMACEUTICAL DESIGN (2007)
Plasminogen binding and activation at the breast cancer cell surface: the integral role of urokinase activity
Gillian E. Stillfried et al.
BREAST CANCER RESEARCH (2007)
Keratin 8 sequence variants in patients with pancreatitis and pancreatic cancer
Matthias Treiber et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2006)
Plasminogen-mediated activation and release of hepatocyte growth factor from extracellular matrix
Hiroto Matsuoka et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2006)
Identification of histone H2B as a regulated plasminogen receptor
Thomas Herren et al.
BIOCHEMISTRY (2006)
CK8 correlates with malignancy in leukoplakia and carcinomas of the head and neck
O Gires et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Matrix metalloproteinases and tumor metastasis
EI Deryugina et al.
CANCER AND METASTASIS REVIEWS (2006)
Cytokeratin 8/18 expression indicates a poor prognosis in squamous cell carcinomas of the oral cavity
T Fillies et al.
BMC CANCER (2006)
An overview of the serpin superfamily
Ruby H. P. Law et al.
GENOME BIOLOGY (2006)
Plasminogen activator inhibitor-1 as a potential marker for the malignancy of colorectal cancer
T Sakakibara et al.
BRITISH JOURNAL OF CANCER (2005)
Significant overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma using real-time quantitative reverse transcription polymerase chain reaction
A Nielsen et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2005)
Integrin αMβ2 orchestrates and accelerates plasminogen activation and fibrinolysis by neutrophils
E Pluskota et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents
A Schweinitz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Specific interaction of tissue-type plasminogen activator (t-PA) with annexin II on the membrane of pancreatic cancer cells activates plasminogen and promotes invasion in vitro
VM Díaz et al.
GUT (2004)
Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D
BK McColl et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Plasminogen binding and cancer: Promises and pitfalls
M Ranson et al.
FRONTIERS IN BIOSCIENCE (2003)
Expression of mucins and cytokeratins in primary carcinomas of the digestive system
MJ Lee et al.
MODERN PATHOLOGY (2003)
Urokinase-type plasminogen activator expression correlates with tumor angiogenesis and poor outcome in gastric cancer
T Kaneko et al.
CANCER SCIENCE (2003)
Inhibitors of the proteolytic activity of urokinase type plasminogen activator
TW Rockway et al.
CURRENT PHARMACEUTICAL DESIGN (2003)
Expression of cytokeratin 8 in lung cancer cell lines and measurement of serum cytokeratin 8 in lung cancer patients
Y Fukunaga et al.
LUNG CANCER (2002)
Insulin-like growth factor-1 inscribes a gene expression profile for angiogenic factors and cancer progression in breast epithelial cells
JS Oh et al.
NEOPLASIA (2002)
High tumor tissue concentration of plasminogen activator inhibitor 2 (PAI-2) is an independent marker for shorter progression-free survival in patients with early stage endometrial cancer
J Nordengren et al.
INTERNATIONAL JOURNAL OF CANCER (2002)
Pooled analysis of prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 8377 breast cancer patients
MP Look et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2002)
Role of the matrix metalloproteinase and plasminogen activator-plasmin systems in angiogenesis
MS Pepper
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2001)
Dedifferentiation of serous ovarian cancer from cystic to solid tumors is associated with increased expression of mRNA for urokinase plasminogen activator (uPA), its receptor (uPAR) and its inhibitor (PAI-1)
C Borgfeldt et al.
INTERNATIONAL JOURNAL OF CANCER (2001)
Urokinase receptor and fibronectin regulate the ERKMAPK to p38MAPK activity ratios that determine carcinoma cell proliferation or dormancy in vivo
JA Aguirre-Ghiso et al.
MOLECULAR BIOLOGY OF THE CELL (2001)
Cancer cell expression of urokinase-type plasminogen activator receptor mRNA in squamous cell carcinomas of the skin
J Romer et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2001)
Structure-directed discovery of potent non-peptidic inhibitors of human urokinase that access a novel binding subsite
VL Nienaber et al.
STRUCTURE (2000)
Unraveling the role of proteases in cancer
JE Koblinski et al.
CLINICA CHIMICA ACTA (2000)
The plasminogen activation system in tumor growth, invasion, and metastasis
PA Andreasen et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2000)
Specific expression of matrix metalloproteinases 1, 3, 9 and 13 associated with invasiveness of breast cancer cells in vitro
M Balduyck et al.
CLINICAL & EXPERIMENTAL METASTASIS (2000)
Share Paper
